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Most available antimicrobial peptides (AMP) prediction methods use common approach for different classes of AMP. Contrary to available approaches, we suggest, that a strategy of prediction should be based on the fact, that there are several…

Biomolecules · Quantitative Biology 2013-10-31 Boris Vishnepolsky , Malak Pirtskhalava

In recent years, there has been increasing interest in developing models and tools to address the complex patterns of connectivity found in brain tissue. Specifically, this is due to a need to understand how emergent properties emerge from…

Neurons and Cognition · Quantitative Biology 2022-04-15 Sean Knight , Navjot Gadda

Traffic prediction has drawn increasing attention in AI research field due to the increasing availability of large-scale traffic data and its importance in the real world. For example, an accurate taxi demand prediction can assist taxi…

Machine Learning · Computer Science 2018-11-06 Huaxiu Yao , Xianfeng Tang , Hua Wei , Guanjie Zheng , Zhenhui Li

Theories of localised pattern formation are important to understand a broad range of natural patterns, but are less well-understood than more established mechanisms of domain-filling pattern formation. Here, we extend recent work on pattern…

Pattern Formation and Solitons · Physics 2025-07-22 Andrew L. Krause , Václav Klika , Edgardo Villar-Sepúlveda , Alan R. Champneys , Eamonn A. Gaffney

The diffusion-driven Turing instability is a potential mechanism for spatial pattern formation in numerous biological and chemical systems. However, engineering these patterns and demonstrating that they are produced by this mechanism is…

Biological Physics · Physics 2025-12-02 Antonio Matas-Gil , Robert G. Endres

Mathematical models play a crucial role in understanding the spread of infectious disease outbreaks and influencing policy decisions. These models aid pandemic preparedness by predicting outcomes under hypothetical scenarios and identifying…

Spike-timing dependent plasticity in biological neural networks has been proven to be important during biological learning process. On the other hand, artificial neural networks use a different way to learn, such as Back-Propagation or…

Neural and Evolutionary Computing · Computer Science 2022-06-29 Shiyuan Li

Objective: The COVID-19 pandemic has created many challenges that need immediate attention. Various epidemiological and deep learning models have been developed to predict the COVID-19 outbreak, but all have limitations that affect the…

Social and Information Networks · Computer Science 2020-12-08 Junyi Gao , Rakshith Sharma , Cheng Qian , Lucas M. Glass , Jeffrey Spaeder , Justin Romberg , Jimeng Sun , Cao Xiao

Many studies have been performed to characterize the dynamics and stability of the microbiome across a range of environmental contexts [Costello et al., 2012, Faust et al., 2015]. For example, it is often of interest to identify time…

Applications · Statistics 2017-12-04 Kris Sankaran , Susan P. Holmes

Spatial transcriptomics (ST) provides crucial insights into tissue micro-environments, but is limited to its high cost and complexity. As an alternative, predicting gene expression from pathology whole slide images (WSI) is gaining…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Mingcheng Qu , Yuncong Wu , Donglin Di , Yue Gao , Tonghua Su , Yang Song , Lei Fan

Antimicrobial protocols - using substances such as antibiotics or disinfectants - remain the preferred option for preventing the spread of pathogenic bacteria. However, bacteria can develop mechanisms to reduce their antimicrobial…

Populations and Evolution · Quantitative Biology 2026-02-17 Nerea Martínez-López , Niclas Nordholt , Frank Schreiber , Míriam R. García

Identifying objective neuroimaging biomarkers to forecast Alzheimer's disease (AD) progression is crucial for timely intervention. However, this task remains challenging due to the complex dysfunctions in the spatio-temporal characteristics…

In multivariate time series (MTS) forecasting, many deep learning based methods have been proposed for modeling dependencies at multiple spatial (inter-variate) or temporal (intra-variate) scales. However, existing methods may fail to model…

Machine Learning · Computer Science 2025-09-03 Binqing Wu , Jianlong Huang , Zongjiang Shang , Ling Chen

Short-term synaptic plasticity (STP) is often regarded as a presynaptic filter of spikes, independent of postsynaptic activity. Recent experiments, however, indicate an associative STP that depends on pre- and postsynaptic coactivation. We…

Neurons and Cognition · Quantitative Biology 2026-05-20 Genki Shimizu , Taro Toyoizumi

With the advancement of GPS and remote sensing technologies, large amounts of geospatial and spatiotemporal data are being collected from various domains, driving the need for effective and efficient prediction methods. Given spatial data…

Machine Learning · Computer Science 2020-12-25 Zhe Jiang

Effects of immune delay on symmetric dynamics are investigated within a model of antigenic variation in malaria. Using isotypic decomposition of the phase space, stability problem is reduced to the analysis of a cubic transcendental…

Chaotic Dynamics · Physics 2012-09-21 K. B. Blyuss , Y. N. Kyrychko

In contemporary data-driven environments, the generation and processing of multivariate time series data is an omnipresent challenge, often complicated by time delays between different time series. These delays, originating from a multitude…

Machine Learning · Computer Science 2024-08-26 Jiajie Wang , Zhiyuan Jerry Lin , Wen Chen

Recent biological experimental findings have shown that synaptic plasticity depends on the relative timing of pre- and post-synaptic spikes and this is called spike-timing-dependent plasticity (STDP). Many authors have claimed that a…

Disordered Systems and Neural Networks · Physics 2007-05-23 Narihisa Matsumoto , Masato Okada

Spatio-temporal pathogen spread is often partially observed at the metapopulation scale. Available data correspond to proxies and are incomplete, censored and heterogeneous. Moreover, representing such biological systems often leads to…

Populations and Evolution · Quantitative Biology 2023-12-04 Gaël Beaunée , Pauline Ezanno , Alain Joly , Pierre Nicolas , Elisabeta Vergu

Test-Time Adaptation (TTA) has recently emerged as a promising approach for tackling the robustness challenge under distribution shifts. However, the lack of consistent settings and systematic studies in prior literature hinders thorough…

Machine Learning · Computer Science 2023-06-07 Hao Zhao , Yuejiang Liu , Alexandre Alahi , Tao Lin