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In many modern machine learning applications, the outcome is expensive or time-consuming to collect while the predictor information is easy to obtain. Semi-supervised learning (SSL) aims at utilizing large amounts of `unlabeled' data along…

Methodology · Statistics 2017-11-16 Jessica Gronsbell , Tianxi Cai

With the increasing availability of electronic health records (EHR) linked with biobank data for translational research, a critical step in realizing its potential is to accurately classify phenotypes for patients. Existing approaches to…

Methodology · Statistics 2024-04-02 Molei Liu , Xinyi Wang , Chuan Hong

In modern machine learning applications, frequent encounters of covariate shift and label scarcity have posed challenges to robust model training and evaluation. Numerous transfer learning methods have been developed to robustly adapt the…

Methodology · Statistics 2022-11-22 Linshanshan Wang , Xuan Wang , Katherine P. Liao , Tianxi Cai

Electronic Health Records (EHR) data, a rich source for biomedical research, have been successfully used to gain novel insight into a wide range of diseases. Despite its potential, EHR is currently underutilized for discovery research due…

Methodology · Statistics 2021-09-14 Yichi Zhang , Molei Liu , Matey Neykov , Tianxi Cai

Automated heart sounds classification is a much-required diagnostic tool in the view of increasing incidences of heart related diseases worldwide. In this study, we conduct a comprehensive study of heart sounds classification by using…

Computer Vision and Pattern Recognition · Computer Science 2020-06-05 Balagopal Unnikrishnan , Pranshu Ranjan Singh , Xulei Yang , Matthew Chin Heng Chua

Electronic Health Records (EHR) offer rich real-world data for personalized medicine, providing insights into disease progression, treatment responses, and patient outcomes. However, their sparsity, heterogeneity, and high dimensionality…

Methodology · Statistics 2025-05-28 Linshanshan Wang , Mengyan Li , Zongqi Xia , Molei Liu , Tianxi Cai

In biomedical studies, it is often desirable to characterize the interactive mode of multiple disease outcomes beyond their marginal risk. Ising model is one of the most popular choices serving for this purpose. Nevertheless, learning…

Methodology · Statistics 2023-11-28 Daiqing Wu , Molei Liu

Cell recognition is a fundamental task in digital histopathology image analysis. Point-based cell recognition (PCR) methods normally require a vast number of annotations, which is extremely costly, time-consuming and labor-intensive.…

Computer Vision and Pattern Recognition · Computer Science 2023-06-16 Zhongyi Shui , Yizhi Zhao , Sunyi Zheng , Yunlong Zhang , Honglin Li , Shichuan Zhang , Xiaoxuan Yu , Chenglu Zhu , Lin Yang

Pseudo-labeling is a commonly used paradigm in semi-supervised learning, yet its application to semi-supervised regression (SSR) remains relatively under-explored. Unlike classification, where pseudo-labels are discrete and confidence-based…

Machine Learning · Computer Science 2025-10-20 Xueqing Sun , Renzhen Wang , Quanziang Wang , Yichen Wu , Xixi Jia , Deyu Meng

Building phenotype models using electronic health record (EHR) data conventionally requires manually labeled cases and controls. Assigning labels is labor intensive and, for some phenotypes, identifying gold-standard controls is…

Graph-based semi-supervised learning has been shown to be one of the most effective approaches for classification tasks from a wide range of domains, such as image classification and text classification, as they can exploit the connectivity…

Computer Vision and Pattern Recognition · Computer Science 2020-04-09 Wanyu Lin , Zhaolin Gao , Baochun Li

Computational phenotyping allows for unsupervised discovery of subgroups of patients as well as corresponding co-occurring medical conditions from electronic health records (EHR). Typically, EHR data contains demographic information,…

Machine Learning · Computer Science 2023-10-18 Florian Becker , Age K. Smilde , Evrim Acar

Optimal performance is critical for decision-making tasks from medicine to autonomous driving, however common performance measures may be too general or too specific. For binary classifiers, diagnostic tests or prognosis at a timepoint,…

Training deep neural networks usually requires a large amount of labeled data to obtain good performance. However, in medical image analysis, obtaining high-quality labels for the data is laborious and expensive, as accurately annotating…

Computer Vision and Pattern Recognition · Computer Science 2020-05-20 Quande Liu , Lequan Yu , Luyang Luo , Qi Dou , Pheng Ann Heng

The rapid expansion of large-scale electronic health record (EHR) data offers unique opportunities to improve the accuracy and efficiency of clinical risk estimation. Yet, because clinical events may occur outside the recording health…

Methodology · Statistics 2026-05-11 Jie Zhou , Enhao Wang , Xuan Wang

Detecting medical conditions from speech acoustics is fundamentally a weakly-supervised learning problem: a single, often noisy, session-level label must be linked to nuanced patterns within a long, complex audio recording. This task is…

Sound · Computer Science 2026-04-21 Xingyuan Li , Mengyue Wu

Semi-supervised learning leverages unlabeled data to enhance model performance, addressing the limitations of fully supervised approaches. Among its strategies, pseudo-supervision has proven highly effective, typically relying on one or…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Negin Ghamsarian , Sahar Nasirihaghighi , Klaus Schoeffmann , Raphael Sznitman

Risk modeling with EHR data is challenging due to a lack of direct observations on the disease outcome, and the high dimensionality of the candidate predictors. In this paper, we develop a surrogate assisted semi-supervised-learning (SAS)…

Statistics Theory · Mathematics 2021-05-05 Jue Hou , Zijian Guo , Tianxi Cai

This paper proposes a novel method of learning by predicting view assignments with support samples (PAWS). The method trains a model to minimize a consistency loss, which ensures that different views of the same unlabeled instance are…

Computer Vision and Pattern Recognition · Computer Science 2021-08-03 Mahmoud Assran , Mathilde Caron , Ishan Misra , Piotr Bojanowski , Armand Joulin , Nicolas Ballas , Michael Rabbat

Machine learning (ML) is increasingly employed in real-world applications like medicine or economics, thus, potentially affecting large populations. However, ML models often do not perform homogeneously, leading to underperformance or,…

Machine Learning · Computer Science 2025-08-28 Tom Siegl , Kutalmış Coşkun , Bjarne C. Hiller , Amin Mirzaei , Florian Lemmerich , Martin Becker
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