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We introduce a novel Bayesian approach for jointly modeling longitudinal cardiovascular disease (CVD) risk factor trajectories, medication use, and time-to-events. Our methodology incorporates longitudinal risk factor trajectories into the…

Methodology · Statistics 2025-03-25 Zeynab Aghabazaz , Michael J Daniels , Donald M Lloyd-Jones , Juned Siddique

Chronic diseases such as diabetes pose significant management challenges, particularly due to the risk of complications like hypoglycemia, which require timely detection and intervention. Continuous health monitoring through wearable…

Machine Learning · Computer Science 2026-01-08 Vaibhav Gupta , Florian Grensing , Beyza Cinar , Maria Maleshkova

Balancing weights have been widely applied to single or monotone missingness due to empirical advantages over likelihood-based methods and inverse probability weighting approaches. This paper considers non-monotone missing data under the…

Methodology · Statistics 2024-12-13 Jianing Dong , Raymond K. W. Wong , Kwun Chuen Gary Chan

Cardiovascular diseases (CVDs) are one of the most common chronic illnesses that affect peoples health. Early detection of CVDs can reduce mortality rates by preventing or reducing the severity of the disease. Machine learning algorithms…

Machine Learning · Computer Science 2021-06-17 Prasannavenkatesan Theerthagiri , Vidya J

Predicting the health risks of patients using Electronic Health Records (EHR) has attracted considerable attention in recent years, especially with the development of deep learning techniques. Health risk refers to the probability of the…

Machine Learning · Computer Science 2022-11-15 Yuxi Liu , Shaowen Qin , Antonio Jimeno Yepes , Wei Shao , Zhenhao Zhang , Flora D. Salim

In today's world, a massive amount of data is available in almost every sector. This data has become an asset as we can use this enormous amount of data to find information. Mainly health care industry contains many data consisting of…

Machine Learning · Computer Science 2022-03-10 Hafsa Binte Kibria , Abdul Matin

Background: Researchers typically identify pregnancies in healthcare data based on observed outcomes (e.g., delivery). This outcome-based approach misses pregnancies that received prenatal care but whose outcomes were not recorded (e.g.,…

Cardiovascular diseases (CVD) and depression exhibit significant comorbidity, which is highly predictive of poor clinical outcomes. Yet, the underlying biological pathways remain challenging to decipher, presumably due to the non-linear…

Early detection of cardiovascular disease risk factors is essential to alter the course of the disease. Previous studies showed that deep learning can successfully be used to detect such risk factors from retinal images. This study uses…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Andrea Prenner

Missing data is a common concern in health datasets, and its impact on good decision-making processes is well documented. Our study's contribution is a methodology for tackling missing data problems using a combination of synthetic dataset…

Machine Learning · Computer Science 2022-11-08 Gift Khangamwa , Terence L. van Zyl , Clint J. van Alten

Cardiovascular disease (CVD) remains the leading cause of death worldwide, requiring urgent development of effective risk assessment methods for timely intervention. While current research has introduced non-invasive and efficient…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Lehan Wang , Hualiang Wang , Chubin Ou , Lushi Chen , Yunyi Liang , Xiaomeng Li

Nonmonotone missing data is a common problem in scientific studies. The conventional ignorability and missing-at-random (MAR) conditions are unlikely to hold for nonmonotone missing data and data analysis can be very challenging with few…

Methodology · Statistics 2022-07-07 Gang Cheng , Yen-Chi Chen , Maureen A. Smith , Ying-Qi Zhao

In this work, we are motivated by the problem of estimating racial disparities in health outcomes, specifically the average controlled difference (ACD) in telomere length between Black and White individuals, using data from the National…

Causal inference methods based on electronic health record (EHR) databases must simultaneously handle confounding and missing data. Vast scholarship exists aimed at addressing these two issues separately, but surprisingly few papers attempt…

Methodology · Statistics 2025-07-28 Luke Benz , Alexander Levis , Sebastien Haneuse

Currently, many researchers and analysts are working toward medical diagnosis enhancement for various diseases. Heart disease is one of the common diseases that can be considered a significant cause of mortality worldwide. Early detection…

Machine Learning · Computer Science 2023-06-02 Salahaldeen Rababa , Asma Yamin , Shuxia Lu , Ashraf Obaidat

Electronic healthcare records (EHR) contain a huge wealth of data that can support the prediction of clinical outcomes. EHR data is often stored and analysed using clinical codes (ICD10, SNOMED), however these can differ across registries…

Machine Learning · Computer Science 2024-12-03 Elizabeth Remfry , Rafael Henkin , Michael R Barnes , Aakanksha Naik

Cardiovascular disease (CVD) continues to be the major cause of death globally, calling for predictive models that not only handle diverse and high-dimensional biomedical signals but also maintain interpretability and privacy. We create a…

Machine Learning · Computer Science 2026-01-13 Rohit Kaushik , Eva Kaushik

Cardiovascular disease (CVD) cohorts collect data longitudinally to study the association between CVD risk factors and event times. An important area of scientific research is to better understand what features of CVD risk factor…

Methodology · Statistics 2024-12-03 Mirajul Islam , Michael J. Daniels , Zeynab Aghabazaz , Juned Siddique

Diet plays a crucial role in health, and understanding the causal effects of dietary patterns is essential for informing public health policy and personalized nutrition strategies. However, causal inference in nutritional epidemiology faces…

Methodology · Statistics 2026-01-26 Dafne Zorzetto , Zizhao Xie , Julian Stamp , Arman Oganisian , Roberta De Vito

Many high dimensional and high-throughput biological datasets have complex sample correlation structures, which include longitudinal and multiple tissue data, as well as data with multiple treatment conditions or related individuals. These…

Methodology · Statistics 2018-08-20 Chris McKennan , Dan Nicolae