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Analysis of brain connectivity is important for understanding how information is processed by the brain. We propose a novel Bayesian vector autoregression (VAR) hierarchical model for analyzing brain connectivity in a resting-state fMRI…

Applications · Statistics 2021-12-09 Bertil Wegmann , Anders Lundquist , Anders Eklund , Mattias Villani

Brain connectivity analysis based on magnetic resonance imaging is crucial for understanding neurological mechanisms. However, edge-based connectivity inference faces significant challenges, particularly the curse of dimensionality when…

Methodology · Statistics 2025-12-23 Zijing Li , Chenhao Zeng , Shufei Ge

Population analyses of functional connectivity have provided a rich understanding of how brain function differs across time, individual, and cognitive task. An important but challenging task in such population analyses is the identification…

Social and Information Networks · Computer Science 2020-08-19 James D. Wilson , Melanie Baybay , Rishi Sankar , Paul Stillman , Abbie M. Popa

Diffusion Tensor Imaging (DTI) is an effective tool for the analysis of structural brain connectivity in normal development and in a broad range of brain disorders. However efforts to derive inherent characteristics of structural brain…

Computational Engineering, Finance, and Science · Computer Science 2018-02-14 Yu Jin , Joseph F. JaJa , Rong Chen , Edward H. Herskovits

Brain disorders are an umbrella term for a group of neurological and psychiatric conditions that have a major effect on thinking, feeling, and acting. These conditions encompass a wide range of conditions. The illnesses in question pose…

Neurons and Cognition · Quantitative Biology 2025-11-11 Aniruddha Saha , Soujanya Hazra , Sanjay Ghosh

EEG-based Brain-Computer Interfaces (BCIs) frequently face spatial specificity limitations in detecting single-trial P300 potentials, a neurophysiological hallmark leveraged for both BCI control and neurodegenerative disease diagnostics. We…

Quantitative Methods · Quantitative Biology 2025-11-05 Eva Guttmann-Flury , Jian Zhao , Mohamad Sawan

Our goal is to model and measure functional and effective (directional) connectivity in multichannel brain physiological signals (e.g., electroencephalograms, local field potentials). The difficulties from analyzing these data mainly come…

Applications · Statistics 2017-12-04 Lechuan Hu , Norbert Fortin , Hernando Ombao

This paper studies change-points in human brain functional connectivity (FC) and seeks patterns that are common across multiple subjects under identical external stimulus. FC relates to the similarity of fMRI responses across different…

Neurons and Cognition · Quantitative Biology 2020-03-05 Mengyu Dai , Zhengwu Zhang , Anuj Srivastava

Gaining insights into the structural and functional mechanisms of the brain has been a longstanding focus in neuroscience research, particularly in the context of understanding and treating neuropsychiatric disorders such as Schizophrenia…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Badhan Mazumder , Lei Wu , Vince D. Calhoun , Dong Hye Ye

The primary motivation and application in this article come from brain imaging studies on cognitive impairment in elderly subjects with brain disorders. We propose a regularized Haar wavelet-based approach for the analysis of…

Applications · Statistics 2014-08-11 Xuejing Wang , Bin Nan , Ji Zhu , Robert Koeppe

In neuroscience, functional brain connectivity describes the connectivity between brain regions that share functional properties. Neuroscientists often characterize it by a time series of covariance matrices between functional measurements…

Methodology · Statistics 2019-07-09 Zhenhua Lin , Dehan Kong , Qiang Sun

Detecting shared neural activity from functional magnetic resonance imaging (fMRI) across individuals exposed to the same stimulus can reveal synchronous brain responses, functional roles of regions, and potential clinical biomarkers.…

Applications · Statistics 2026-04-24 Spencer Wadsworth , Nabin Koirala , Nicole Landi , Ofer Harel

The human brain can be conceptualized as a dynamical system. Utilizing resting state fMRI time series imaging, we can study the underlying dynamics at ear-marked Regions of Interest (ROIs) to understand structure or lack thereof. This…

Computer Vision and Pattern Recognition · Computer Science 2023-12-01 Ninad Aithal , Chakka Sai Pradeep , Neelam Sinha

Purpose: Diffusion weighted MRI (dMRI) and its models of neural structure provide insight into human brain organization and variations in white matter. A recent study by McMaster, et al. showed that complex graph measures of the connectome,…

Functional connectomes capture brain interactions via synchronized fluctuations in the functional magnetic resonance imaging signal. If measured during rest, they map the intrinsic functional architecture of the brain. With task-driven…

Neurons and Cognition · Quantitative Biology 2013-04-16 Gaël Varoquaux , R. C. Craddock

Imaging studies suggest that the functional connectivity patterns of resting state networks (RS-networks) reflect underlying structural connectivity (SC). If the connectome constrains how brain areas are functionally connected, the…

Neurons and Cognition · Quantitative Biology 2016-02-25 Andreas Spiegler , Enrique C. A. Hansen , Christophe Bernard , Anthony R. McIntosh , Viktor K. Jirsa

Identifying preictal states -- periods during which seizures are more likely to occur -- remains a central challenge in clinical computational neuroscience. In this study, we introduce a novel framework that embeds functional brain…

Neurons and Cognition · Quantitative Biology 2025-05-21 Steven Rico-Aparicio , Martin Guillemaud , Alice Longhena , Vincent Navarro , Louis Cousyn , Mario Chavez

This article proposes a Bayesian approach to regression with a continuous scalar response and an undirected network predictor. Undirected network predictors are often expressed in terms of symmetric adjacency matrices, with rows and columns…

Methodology · Statistics 2018-03-29 Sharmistha Guha , Abel Rodriguez

We propose Boundary-RL, a novel weakly supervised segmentation method that utilises only patch-level labels for training. We envision the segmentation as a boundary detection problem, rather than a pixel-level classification as in previous…

Computer Vision and Pattern Recognition · Computer Science 2023-08-23 Weixi Yi , Vasilis Stavrinides , Zachary M. C. Baum , Qianye Yang , Dean C. Barratt , Matthew J. Clarkson , Yipeng Hu , Shaheer U. Saeed

It is well known that the visual information represented in the simple cells of the primary visual cortex V1 is spatially localized, orientation-sensitive and bandpass-filtered. In addition, the visual information represented is subsampled.…

Medical Physics · Physics 2024-01-01 Antonio González-López