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Harm reporting in Artificial Intelligence (AI) currently lacks a structured process for disclosing and addressing algorithmic flaws, relying largely on an ad-hoc approach. This contrasts sharply with the well-established Coordinated…

Artificial Intelligence · Computer Science 2024-07-29 Sven Cattell , Avijit Ghosh , Lucie-Aimée Kaffee

Machine learning in healthcare requires effective representation of structured medical codes, but current methods face a trade off: knowledge graph based approaches capture formal relationships but miss real world patterns, while data…

Machine Learning · Computer Science 2025-10-07 Ahmed Elhussein , Paul Meddeb , Abigail Newbury , Jeanne Mirone , Martin Stoll , Gamze Gursoy

Publicly available collections of drug-like molecules have grown to comprise 10s of billions of possibilities in recent history due to advances in chemical synthesis. Traditional methods for identifying "hit" molecules from a large…

Multimodal federated learning holds immense potential for collaboratively training models from multiple sources without sharing raw data, addressing both data scarcity and privacy concerns, two key challenges in healthcare. A major…

Machine Learning · Computer Science 2025-05-27 Pranav Poudel , Aavash Chhetri , Prashnna Gyawali , Georgios Leontidis , Binod Bhattarai

Self-driving labs are transforming drug discovery by enabling automated, AI-guided experimentation, but they face challenges in orchestrating complex workflows, integrating diverse instruments and AI models, and managing data efficiently.…

Software Engineering · Computer Science 2025-04-02 Yao Fehlis , Paul Mandel , Charles Crain , Betty Liu , David Fuller

Like any field of empirical science, AI may be approached axiomatically. We formulate requirements for a general-purpose, human-level AI system in terms of postulates. We review the methodology of deep learning, examining the explicit and…

Artificial Intelligence · Computer Science 2018-06-26 Eray Özkural

In healthcare, multimodal data is prevalent and requires to be comprehensively analyzed before diagnostic decisions, including medical images, clinical reports, etc. However, current large-scale artificial intelligence models predominantly…

Artificial Intelligence · Computer Science 2023-06-29 Weihua Liu , Yong Zuo

This work focuses on the limitations about the insufficient fitting capability of current quantum machine learning methods, which results from the over-reliance on a single data embedding strategy. We propose a novel quantum machine…

Quantum Physics · Physics 2025-04-01 Siyu Han , Lihan Jia , Lanzhe Guo

Herein, we present the application of MEGAN, our explainable AI (xAI) model, for the identification of small colloidally aggregating molecules (SCAMs). This work offers solutions to the long-standing problem of false positives caused by…

Biomolecules · Quantitative Biology 2025-05-28 Hunter Sturm , Jonas Teufel , Kaitlin A. Isfeld , Pascal Friederich , Rebecca L. Davis

The precise prediction of molecular properties is essential for advancements in drug development, particularly in virtual screening and compound optimization. The recent introduction of numerous deep learning-based methods has shown…

Machine Learning · Computer Science 2024-07-01 Taojie Kuang , Pengfei Liu , Zhixiang Ren

Biomedical data is inherently multimodal, consisting of electronic health records, medical imaging, digital pathology, genome sequencing, wearable sensors, and more. The application of artificial intelligence tools to these multifaceted…

Machine Learning · Computer Science 2024-08-26 Shentong Mo , Paul Pu Liang

Organizations are collecting increasingly large amounts of data for data driven decision making. These data are often dumped into a centralized repository, e.g., a data lake, consisting of thousands of structured and unstructured datasets.…

Artificial Intelligence · Computer Science 2023-07-18 Mohamed Y. Eltabakh , Mayuresh Kunjir , Ahmed Elmagarmid , Mohammad Shahmeer Ahmad

The exponential growth of scientific knowledge has created significant barriers to cross-disciplinary knowledge discovery, synthesis and research collaboration. In response to this challenge, we present BioSage, a novel compound AI…

The integration of artificial intelligence (AI) in early-stage drug discovery offers unprecedented opportunities for exploring chemical space and accelerating hit-to-lead optimization. However, docking optimization in generative approaches…

Quantitative Methods · Quantitative Biology 2025-10-03 Ekaterina Podplutova , Anastasia Vepreva , Olga A. Konovalova , Vladimir Vinogradov , Dmitrii O. Shkil , Andrei Dmitrenko

Generative retrieval is an emerging approach in information retrieval that generates identifiers (IDs) of target data based on a query, providing an efficient alternative to traditional embedding-based retrieval methods. However, existing…

Information Retrieval · Computer Science 2025-06-09 Sungyeon Kim , Xinliang Zhu , Xiaofan Lin , Muhammet Bastan , Douglas Gray , Suha Kwak

Disordered proteins play essential roles in myriad cellular processes, yet their structural characterization remains a major challenge due to their dynamic and heterogeneous nature. We here present a community-driven initiative to address…

Knowledge Distillation (KD) is a popular technique to transfer knowledge from a teacher model or ensemble to a student model. Its success is generally attributed to the privileged information on similarities/consistency between the class…

Machine Learning · Computer Science 2021-07-02 Zhen Huang , Xu Shen , Jun Xing , Tongliang Liu , Xinmei Tian , Houqiang Li , Bing Deng , Jianqiang Huang , Xian-Sheng Hua

Cognitive Diagnosis Models (CDMs) are designed to assess students' cognitive states by analyzing their performance across a series of exercises. However, existing CDMs often struggle with diagnosing infrequent students and exercises due to…

Artificial Intelligence · Computer Science 2025-02-11 Zhiang Dong , Jingyuan Chen , Fei Wu

Online HD map construction is a fundamental task in autonomous driving systems, aiming to acquire semantic information of map elements around the ego vehicle based on real-time sensor inputs. Recently, several approaches have achieved…

Computer Vision and Pattern Recognition · Computer Science 2025-08-25 Ziyang Yan , Ruikai Li , Zhiyong Cui , Bohan Li , Han Jiang , Yilong Ren , Aoyong Li , Zhenning Li , Sijia Wen , Haiyang Yu

The prevailing model for disseminating scientific knowledge relies on individual publications dispersed across numerous journals and archives. This legacy system is ill suited to the recent exponential proliferation of publications,…