Related papers: Attractor identification in asynchronous Boolean d…
Boolean networks at the critical point have been a matter of debate for many years as, e.g., scaling of number of attractor with system size. Recently it was found that this number scales superpolynomially with system size, contrary to a…
We introduce a numerical method to study random Boolean networks with asynchronous stochas- tic update. Each node in the network of states starts with equal occupation probability and this probability distribution then evolves to a steady…
We present new applications of parity inversion and time-reversal to the emergence of complex behavior from simple dynamical rules in stochastic discrete models. Our parity-based encoding of causal relationships and time-reversal…
We consider Boolean networks with interaction graphs partitioned into strongly connected components, which we call strong modules. This type of network decomposition has been considered in the literature, primarily from the perspective of…
Using analytic arguments, we show that dynamical attractor periods in large critical Boolean networks are power-law distributed. Our arguments are based on the method of relevant components, which focuses on the behavior of the nodes that…
Biological processes, including cell differentiation, organism development, and disease progression, can be interpreted as attractors (fixed points or limit cycles) of an underlying networked dynamical system. In this paper, we study the…
Asymptotic behaviors are often of particular interest when analyzing Boolean networks that represent biological systems such as signal trans- duction or gene regulatory networks. Methods based on a generalization of the steady state notion,…
In previous works, we introduced the notion of dominant vertices in the context of dynamical systems on networks. This is a set of nodes in the underlying network whose evolution determines the whole network's dynamics after a transient…
The attractors of Boolean networks and their basins have been shown to be highly relevant for model validation and predictive modelling, e.g., in systems biology. Yet there are currently very few tools available that are able to compute and…
Biological systems operate under persistent noise, which can alter system states and induce transitions between attractors. Here, we study the attractor dynamics of Boolean networks focusing on the transitions between attractors induced by…
In this paper we study the dynamical behavior of Boolean networks with firing memory, namely Boolean networks whose vertices are updated synchronously depending on their proper Boolean local transition functions so that each vertex remains…
How can we uncover the natural communities in a real network that allows insight into its underlying structure and also potential functions? In this paper, we introduce a new community detection algorithm, called Attractor, which…
This paper details a method for optimising the size of Boolean automata networks in order to compute their attractors under the parallel update schedule. This method relies on the formalism of modules introduced recently that allows for…
We study the properties of the distance between attractors in Random Boolean Networks, a prominent model of genetic regulatory networks. We define three distance measures, upon which attractor distance matrices are constructed and their…
This study presents a method, along with its algorithmic and computational framework implementation, and performance verification for dynamical system identification. The approach incorporates insights from phase space structures, such as…
Boolean networks are a popular modeling framework in computational biology to capture the dynamics of molecular networks, such as gene regulatory networks. It has been observed that many published models of such networks are defined by…
The deterministic dynamics of randomly connected neural networks are studied, where a state of binary neurons evolves according to a discreet-time synchronous update rule. We give a theoretical support that the overlap of systems' states…
Boolean networks are special types of finite state time-discrete dynamical systems. A Boolean network can be described by a function from an n-dimensional vector space over the field of two elements to itself. A fundamental problem in…
We study Boolean networks which are simple spatial models of the highly conserved Delta-Notch system. The models assume the inhibition of Delta in each cell by Notch in the same cell, and the activation of Notch in presence of Delta in…
The review presents a parameter switching algorithm and his applications which allows numerical approximation of any attractor of a class of continuous-time dynamical systems depending linearly on a real parameter. The considered classes of…