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We present a graphical, knowledge-based method for reviewing treatment-emergent adverse events (AEs) in clinical trials. The approach enhances MedDRA by adding a hidden medical knowledge layer (Safeterm) that captures semantic relationships…

Computation and Language · Computer Science 2025-11-25 Francois Vandenhende , Anna Georgiou , Michalis Georgiou , Theodoros Psaras , Ellie Karekla , Elena Hadjicosta

Objective: Modelling the associations from high-throughput experimental molecular data has provided unprecedented insights into biological pathways and signalling mechanisms. Graphical models and networks have especially proven to be useful…

Machine Learning · Statistics 2013-04-24 Marco Scutari , Radhakrishnan Nagarajan

Machine learning models for graphs in real-world applications are prone to two primary types of uncertainty: (1) those that arise from incomplete and noisy data and (2) those that arise from uncertainty of the model in its output. These…

Machine Learning · Computer Science 2024-12-10 Zohair Shafi , Germans Savcisens , Tina Eliassi-Rad

Cyberterrorism poses a formidable threat to digital infrastructures, with increasing reliance on encrypted, decentralized platforms that obscure threat actor activity. To address the challenge of analyzing such adversarial networks while…

Cryptography and Security · Computer Science 2025-05-23 Anas Ali , Mubashar Husain , Peter Hans

Link prediction in complex networks has attracted considerable attention from interdisciplinary research communities, due to its ubiquitous applications in biological networks, social networks, transportation networks, telecommunication…

Social and Information Networks · Computer Science 2020-12-22 Ece C. Mutlu , Toktam A. Oghaz , Amirarsalan Rajabi , Ivan Garibay

Attack graphs are a powerful tool for security risk assessment by analysing network vulnerabilities and the paths attackers can use to compromise network resources. The uncertainty about the attacker's behaviour makes Bayesian networks…

Cryptography and Security · Computer Science 2016-11-07 Luis Muñoz-González , Daniele Sgandurra , Martín Barrère , Emil Lupu

The task of link prediction for knowledge graphs is to predict missing relationships between entities. Knowledge graph embedding, which aims to represent entities and relations of a knowledge graph as low dimensional vectors in a continuous…

Artificial Intelligence · Computer Science 2022-04-26 Yanhui Peng , Jing Zhang

The rapid evolution of cyber threats has outpaced traditional detection methodologies, necessitating innovative approaches capable of addressing the adaptive and complex behaviors of modern adversaries. A novel framework was introduced,…

Cryptography and Security · Computer Science 2025-08-11 Ignatius Rollere , Caspian Hartsfield , Seraphina Courtenay , Lucian Fenwick , Aurelia Grunwald

Recently, the surge in popularity of Internet of Things (IoT), mobile devices, social media, etc. has opened up a large source for graph data. Graph embedding has been proved extremely useful to learn low-dimensional feature representations…

Machine Learning · Computer Science 2020-09-01 Kaiyang Li , Guangchun Luo , Yang Ye , Wei Li , Shihao Ji , Zhipeng Cai

This paper studies aligning knowledge graphs from different sources or languages. Most existing methods train supervised methods for the alignment, which usually require a large number of aligned knowledge triplets. However, such a large…

Machine Learning · Computer Science 2019-07-09 Meng Qu , Jian Tang , Yoshua Bengio

This paper explores recommender systems in social networks which leverage information such as item rating, intra-item similarities, and trust graph. We demonstrate that item-rating information is more influential than other information…

Information Retrieval · Computer Science 2025-02-25 Paras Stefanopoulos , Sourin Chatterjee , Ahad N. Zehmakan

Given a natural language phrase, relation linking aims to find a relation (predicate or property) from the underlying knowledge graph to match the phrase. It is very useful in many applications, such as natural language question answering,…

Artificial Intelligence · Computer Science 2019-10-25 Weiguo Zheng , Mei Zhang

Cyber threat intelligence (CTI) is being used to search for indicators of attacks that might have compromised an enterprise network for a long time without being discovered. To have a more effective analysis, CTI open standards have…

Cryptography and Security · Computer Science 2019-10-02 Sadegh M. Milajerdi , Birhanu Eshete , Rigel Gjomemo , V. N. Venkatakrishnan

Graph is a natural representation of data for a variety of real-word applications, such as knowledge graph mining, social network analysis and biological network comparison. For these applications, graph embedding is crucial as it provides…

Machine Learning · Computer Science 2020-01-24 Bitan Hou , Yujing Wang , Ming Zeng , Shan Jiang , Ole J. Mengshoel , Yunhai Tong , Jing Bai

Deep learning models on graphs have achieved remarkable performance in various graph analysis tasks, e.g., node classification, link prediction, and graph clustering. However, they expose uncertainty and unreliability against the…

Machine Learning · Computer Science 2022-04-06 Liang Chen , Jintang Li , Jiaying Peng , Tao Xie , Zengxu Cao , Kun Xu , Xiangnan He , Zibin Zheng , Bingzhe Wu

Interpreting the massive volume of security alerts is a significant challenge in Security Operations Centres (SOCs). Effective contextualisation is important, enabling quick distinction between genuine threats and benign activity to…

Cryptography and Security · Computer Science 2025-09-19 Magnus Wiik Eckhoff , Peter Marius Flydal , Siem Peters , Martin Eian , Jonas Halvorsen , Vasileios Mavroeidis , Gudmund Grov

Knowledge graphs (KGs) consisting of triples are always incomplete, so it's important to do Knowledge Graph Completion (KGC) by predicting missing triples. Multi-Source KG is a common situation in real KG applications which can be viewed as…

Computation and Language · Computer Science 2020-10-27 Mingyang Chen , Wen Zhang , Zonggang Yuan , Yantao Jia , Huajun Chen

Many models learn representations of knowledge graph data by exploiting its low-rank latent structure, encoding known relations between entities and enabling unknown facts to be inferred. To predict whether a relation holds between…

Machine Learning · Computer Science 2021-01-19 Carl Allen , Ivana Balažević , Timothy Hospedales

Knowledge graphs suffer from sparsity which degrades the quality of representations generated by various methods. While there is an abundance of textual information throughout the web and many existing knowledge bases, aligning information…

Computation and Language · Computer Science 2021-04-13 Saed Rezayi , Handong Zhao , Sungchul Kim , Ryan A. Rossi , Nedim Lipka , Sheng Li

In clinical treatment, identifying potential adverse reactions of drugs can help assist doctors in making medication decisions. In response to the problems in previous studies that features are high-dimensional and sparse, independent…

Quantitative Methods · Quantitative Biology 2024-07-30 Yufeng Li , Wenchao Zhao , Bo Dang , Xu Yan , Weimin Wang , Min Gao , Mingxuan Xiao