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A representative model in integrative analysis of two high-dimensional correlated datasets is to decompose each data matrix into a low-rank common matrix generated by latent factors shared across datasets, a low-rank distinctive matrix…

Machine Learning · Statistics 2022-04-06 Hai Shu , Zhe Qu

In multicenter biomedical research, integrating data from multiple decentralized sites provides more robust and generalizable findings due to its larger sample size and the ability to account for the between-site heterogeneity. However,…

Methodology · Statistics 2025-12-29 Xiaokang Liu , Yuchen Yang , Yifei Sun , Jiang Bian , Yanyuan Ma , Raymond J. Carroll , Yong Chen

Deep neural networks have shown the ability to extract universal feature representations from data such as images and text that have been useful for a variety of learning tasks. However, the fruits of representation learning have yet to be…

Machine Learning · Computer Science 2023-03-28 Liam Collins , Hamed Hassani , Aryan Mokhtari , Sanjay Shakkottai

Machine learning models can fail on subgroups that are underrepresented during training. While techniques such as dataset balancing can improve performance on underperforming groups, they require access to training group annotations and can…

Machine Learning · Computer Science 2024-06-25 Saachi Jain , Kimia Hamidieh , Kristian Georgiev , Andrew Ilyas , Marzyeh Ghassemi , Aleksander Madry

Important objectives in cancer research are the prediction of a patient's risk based on molecular measurements such as gene expression data and the identification of new prognostic biomarkers (e.g. genes). In clinical practice, this is…

Applications · Statistics 2020-04-17 Katrin Madjar , Manuela Zucknick , Katja Ickstadt , Jörg Rahnenführer

This paper introduces a new data analysis method for big data using a newly defined regression model named multiple model linear regression(MMLR), which separates input datasets into subsets and construct local linear regression models of…

Machine Learning · Computer Science 2023-08-25 Bohan Lyu , Jianzhong Li

Modern data sets, such as those in healthcare and e-commerce, are often derived from many individuals or systems but have insufficient data from each source alone to separately estimate individual, often high-dimensional, model parameters.…

Machine Learning · Computer Science 2024-11-14 Maryann Rui , Thibaut Horel , Munther Dahleh

Many data sets contain an inherent multilevel structure, for example, because of repeated measurements of the same observational units. Taking this structure into account is critical for the accuracy and calibration of any statistical…

Methodology · Statistics 2020-05-07 Topi Paananen , Alejandro Catalina , Paul-Christian Bürkner , Aki Vehtari

A main challenge of data-driven sciences is how to make maximal use of the progressively expanding databases of experimental datasets in order to keep research cumulative. We introduce the idea of a modeling-based dataset retrieval engine…

Quantitative Methods · Quantitative Biology 2015-06-19 Ali Faisal , Jaakko Peltonen , Elisabeth Georgii , Johan Rung , Samuel Kaski

In this manuscript, we investigate the concept of the mean response for a treatment group mean as well as its estimation and prediction for generalized linear models with a subject-wise random effect. Generalized linear models are commonly…

Applications · Statistics 2019-11-05 Jiexin Duan , Michael Levine , Junxiang Luo , Yongming Qu

One important problem in microbiome analysis is to identify the bacterial taxa that are associated with a response, where the microbiome data are summarized as the composition of the bacterial taxa at different taxonomic levels. This paper…

Applications · Statistics 2016-03-04 Pixu Shi , Anru Zhang , Hongzhe Li

Research in modern data-driven dynamical systems is typically focused on the three key challenges of high dimensionality, unknown dynamics, and nonlinearity. The dynamic mode decomposition (DMD) has emerged as a cornerstone for modeling…

Fluid Dynamics · Physics 2022-04-27 Peter J. Baddoo , Benjamin Herrmann , Beverley J. McKeon , Steven L. Brunton

Randomization, as a key technique in clinical trials, can eliminate sources of bias and produce comparable treatment groups. In randomized experiments, the treatment effect is a parameter of general interest. Researchers have explored the…

Methodology · Statistics 2023-12-05 Fuyi Tu , Wei Ma , Hanzhong Liu

Circuit discovery aims to explain how language models (LMs) implement a specific task by localizing and interpreting a circuit, a computational subgraph responsible for the LM's behavior. Existing circuit discovery methods are…

Artificial Intelligence · Computer Science 2026-05-12 Daking Rai , Mor Geva , Ziyu Yao

In this paper we explore different regression models based on Clusterwise Linear Regression (CLR). CLR aims to find the partition of the data into $k$ clusters, such that linear regressions fitted to each of the clusters minimize overall…

Machine Learning · Computer Science 2018-05-01 Igor Gitman , Jieshi Chen , Eric Lei , Artur Dubrawski

We propose generalized additive partial linear models for complex data which allow one to capture nonlinear patterns of some covariates, in the presence of linear components. The proposed method improves estimation efficiency and increases…

Statistics Theory · Mathematics 2014-05-26 Li Wang , Lan Xue , Annie Qu , Hua Liang

We describe a data-driven discovery method that leverages Simpson's paradox to uncover interesting patterns in behavioral data. Our method systematically disaggregates data to identify subgroups within a population whose behavior deviates…

Computers and Society · Computer Science 2018-05-09 Nazanin Alipourfard , Peter G. Fennell , Kristina Lerman

In multivariate time series systems, key insights can be obtained by discovering lead-lag relationships inherent in the data, which refer to the dependence between two time series shifted in time relative to one another, and which can be…

Machine Learning · Statistics 2023-09-20 Yichi Zhang , Mihai Cucuringu , Alexander Y. Shestopaloff , Stefan Zohren

Symbolic regression is a machine learning technique that can learn the governing formulas of data and thus has the potential to transform scientific discovery. However, symbolic regression is still limited in the complexity and…

Machine Learning · Computer Science 2023-05-30 Michael Zhang , Samuel Kim , Peter Y. Lu , Marin Soljačić

We address the problem of data-driven pattern identification and outlier detection in time series. To this end, we use singular value decomposition (SVD) which is a well-known technique to compute a low-rank approximation for an arbitrary…

Methodology · Statistics 2019-03-12 Abdolrahman Khoshrou , Eric J. Pauwels