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200 papers

Data commons collate data with cloud computing infrastructure and commonly used software services, tools and applications to create biomedical resources for the large-scale management, analysis, harmonization, and sharing of biomedical…

Genomics · Quantitative Biology 2018-12-27 Robert L. Grossman

Enterprise data typically involves multiple heterogeneous data sources and external data that respectively record business activities, transactions, customer demographics, status, behaviors, interactions and communications with the…

Machine Learning · Computer Science 2021-12-06 Longbing Cao , Chengzhang Zhu

Assessing where and how information is stored in biological networks (such as neuronal and genetic networks) is a central task both in neuroscience and in molecular genetics, but most available tools focus on the network's structure as…

Information Theory · Computer Science 2023-02-24 Clifford Bohm , Douglas Kirkpatrick , Victoria Cao , Christoph Adami

Encoding models that predict brain response patterns to stimuli are one way to capture this relationship between variability in bottom-up neural systems and individual's behavior or pathological state. However, they generally need a large…

Quantitative Methods · Quantitative Biology 2022-05-17 Zijin Gu , Keith Jamison , Mert Sabuncu , Amy Kuceyeski

NetFlow data is a popular network log format used by many network analysts and researchers. The advantages of using NetFlow over deep packet inspection are that it is easier to collect and process, and it is less privacy intrusive. Many…

Machine Learning · Computer Science 2025-01-09 Clinton Cao , Annibale Panichella , Sicco Verwer , Agathe Blaise , Filippo Rebecchi

Clinical coding is the task of transforming medical information in a patient's health records into structured codes so that they can be used for statistical analysis. This is a cognitive and time-consuming task that follows a standard…

Computation and Language · Computer Science 2022-10-11 Hang Dong , Matúš Falis , William Whiteley , Beatrice Alex , Joshua Matterson , Shaoxiong Ji , Jiaoyan Chen , Honghan Wu

Biological neural networks (BNNs) have been established as a powerful and adaptive substrate that offer the potential for incredibly energy and data efficient information processing with distinct learning mechanisms. Yet a core challenge to…

Objectives: The vast and complex nature of human genomic sequencing data presents challenges for effective analysis. This review aims to investigate the application of Natural Language Processing (NLP) techniques, particularly Large…

Genomics · Quantitative Biology 2025-02-28 Shuyan Cheng , Yishu Wei , Yiliang Zhou , Zihan Xu , Drew N Wright , Jinze Liu , Yifan Peng

Electroencephalogram (EEG) decoding aims to identify the perceptual, semantic, and cognitive content of neural processing based on non-invasively measured brain activity. Traditional EEG decoding methods have achieved moderate success when…

Signal Processing · Electrical Eng. & Systems 2022-03-09 Xun Chen , Chang Li , Aiping Liu , Martin J. McKeown , Ruobing Qian , Z. Jane Wang

Background: Everything as Code (EaC) is an emerging paradigm aiming to codify all aspects of modern software systems. Despite its growing popularity, comprehensive industry standards and peer-reviewed research clarifying its scope and…

Software Engineering · Computer Science 2025-07-08 Haoran Wei , Nazim Madhavji , John Steinbacher

Over the past several years, DNA sequencing has emerged as one of the driving forces in life-sciences, paving the way for affordable and accurate whole genome sequencing. As genomes represent the entirety of an organism's hereditary…

Cryptography and Security · Computer Science 2015-02-17 Emiliano De Cristofaro

In this white paper, we present AlphaEvolve, an evolutionary coding agent that substantially enhances capabilities of state-of-the-art LLMs on highly challenging tasks such as tackling open scientific problems or optimizing critical pieces…

Identifying the complete set of functional elements within the human genome would be a windfall for multiple areas of biological research including medicine, molecular biology, and evolution. Complete knowledge of function would aid in the…

Populations and Evolution · Quantitative Biology 2015-11-24 Daniel R. Schrider , Andrew D. Kern

Chromosome enumeration is an essential but tedious procedure in karyotyping analysis. To automate the enumeration process, we develop a chromosome enumeration framework, DeepACEv2, based on the region based object detection scheme. The…

Computer Vision and Pattern Recognition · Computer Science 2020-07-21 Li Xiao , Chunlong Luo , Tianqi Yu , Yufan Luo , Manqing Wang , Fuhai Yu , Yinhao Li , Chan Tian , Jie Qiao

Medical coding translates free-text clinical documentation into standardized codes drawn from classification systems that contain tens of thousands of entries and are updated annually. It is central to billing, clinical research, and…

Artificial Intelligence · Computer Science 2026-04-01 Joakim Edin , Andreas Motzfeldt , Simon Flachs , Lars Maaløe

Visual encoding and decoding models act as gateways to understanding the neural mechanisms underlying human visual perception. Typically, visual encoding models that predict brain activity from stimuli and decoding models that reproduce…

Machine Learning · Computer Science 2026-04-14 Weijian Mai , Mu Nan , Yu Zhu , Jiahang Cao , Rui Zhang , Yuqin Dai , Chunfeng Song , Andrew F. Luo , Jiamin Wu

Human genomic data carry unique information about an individual and offer unprecedented opportunities for healthcare. The clinical interpretations derived from large genomic datasets can greatly improve healthcare and pave the way for…

Cryptography and Security · Computer Science 2022-09-19 Mohammed Alghazwi , Fatih Turkmen , Joeri van der Velde , Dimka Karastoyanova

Our genomes influence nearly every aspect of human biology from molecular and cellular functions to phenotypes in health and disease. Human genetics studies have now associated hundreds of thousands of differences in our DNA sequence…

Other Quantitative Biology · Quantitative Biology 2023-07-27 IGVF Consortium

Predicting gene function from its DNA sequence is a fundamental challenge in biology. Many deep learning models have been proposed to embed DNA sequences and predict their enzymatic function, leveraging information in public databases…

Determining the types of neurons within a nervous system plays a significant role in the analysis of brain connectomics and the investigation of neurological diseases. However, the efficiency of utilizing anatomical, physiological, or…

Neurons and Cognition · Quantitative Biology 2024-03-27 Minghui Liao , Guojia Wan , Bo Du