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The hypothalamus is a small structure located in the center of the brain and is involved in significant functions such as sleeping, temperature, and appetite control. Various neurological disorders are also associated with hypothalamic…

We describe a new method to automatically discriminate between patients with Alzheimer's disease (AD) or mild cognitive impairment (MCI) and elderly controls, based on multidimensional classification of hippocampal shape features. This…

Background and Objective: Biometric measurements of fetal head are important indicators for maternal and fetal health monitoring during pregnancy. 3D ultrasound (US) has unique advantages over 2D scan in covering the whole fetal head and…

Image and Video Processing · Electrical Eng. & Systems 2020-04-29 Xin Yang , Xu Wang , Yi Wang , Haoran Dou , Shengli Li , Huaxuan Wen , Yi Lin , Pheng-Ann Heng , Dong Ni

Deep learning methods have significantly advanced medical image segmentation, yet their success hinges on large volumes of manually annotated data, which require specialized expertise for accurate labeling. Additionally, these methods often…

Image and Video Processing · Electrical Eng. & Systems 2024-09-04 Wangang Cheng , Guanghua He , Keli Hu , Mingyu Fang , Liang Dong , Zhong Li , Hancan Zhu

Statistical learning has been proposed as a mechanism to structure and segment the continuous flow of information in several sensory modalities. Previous studies proposed that the medial temporal lobe, and in particular the hippocampus, may…

Automatic segmentation methods are important tools for quantitative analysis of Magnetic Resonance Images (MRI). Recently, patch-based label fusion approaches have demonstrated state-of-the-art segmentation accuracy. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Rémi Giraud , Vinh-Thong Ta , Nicolas Papadakis , José V. Manjón , D. Louis Collins , Pierrick Coupé , Alzheimer's Disease Neuroimaging Initiative

Tissue loss in the hippocampi has been heavily correlated with the progression of Alzheimer's Disease (AD). The shape and structure of the hippocampus are important factors in terms of early AD diagnosis and prognosis by clinicians.…

Image and Video Processing · Electrical Eng. & Systems 2022-03-03 Lukas Folle , Sulaiman Vesal , Nishant Ravikumar , Andreas Maier

The hippocampus encodes space through a striking gradient of place field sizes along its dorsal-ventral axis, yet the principles generating this continuous gradient from discrete grid cell inputs remain debated. We propose a unified…

Neurons and Cognition · Quantitative Biology 2025-06-06 Shujun Zhou , Guozhang Chen

Alzheimer's disease progression prediction is critical for patients with early Mild Cognitive Impairment (MCI) to enable timely intervention and improve their quality of life. While existing progression prediction techniques demonstrate…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Zhongying Deng , Shujun Wang , Angelica I Aviles-Rivero , Zoe Kourtzi , Carola-Bibiane Schönlieb

To characterize lobar and segmental airway volume differences between systemic lupus erythematosus (SLE) patients with interstitial lung disease (ILD) and those without ILD (non-ILD) using a deep learning-based approach on non-contrast…

Image and Video Processing · Electrical Eng. & Systems 2026-03-19 Sirong Piao , Ying Ming , Ruijie Zhao , Jiaru Wang , Ran Xiao , Rui Zhao , Zicheng Liao , Qiqi Xu , Shaoze Luo , Bing Li , Lin Li , Zhuangfei Ma , Fuling Zheng , Wei Song

This report provides an overview of the current state of the art deep learning architectures and optimisation techniques, and uses the ADNI hippocampus MRI dataset as an example to compare the effectiveness and efficiency of different…

Machine Learning · Computer Science 2015-05-11 Matthew Lai

Kidney abnormality segmentation has important potential to enhance the clinical workflow, especially in settings requiring quantitative assessments. Kidney volume could serve as an important biomarker for renal diseases, with changes in…

The majority of ML research concerns slow, statistical learning of i.i.d. samples from large, labelled datasets. Animals do not learn this way. An enviable characteristic of animal learning is `episodic' learning - the ability to memorise a…

Neural and Evolutionary Computing · Computer Science 2020-03-26 Gideon Kowadlo , Abdelrahman Ahmed , David Rawlinson

Large language models (LLMs) struggle with maintaining coherence in extended conversations spanning hundreds of turns, despite performing well within their context windows. This paper introduces HEMA (Hippocampus-Inspired Extended Memory…

Computation and Language · Computer Science 2025-04-24 Kwangseob Ahn

Comprehending extended audiovisual experiences remains challenging for computational systems, particularly temporal integration and cross-modal associations fundamental to human episodic memory. We introduce HippoMM, a computational…

Multimedia · Computer Science 2026-04-03 Yueqian Lin , Jingyang Zhang , Qinsi Wang , Hancheng Ye , Yuzhe Fu , Yudong Liu , Hai "Helen" Li , Yiran Chen

Whole brain segmentation is an important neuroimaging task that segments the whole brain volume into anatomically labeled regions-of-interest. Convolutional neural networks have demonstrated good performance in this task. Existing…

Image and Video Processing · Electrical Eng. & Systems 2021-11-01 Yeshu Li , Jonathan Cui , Yilun Sheng , Xiao Liang , Jingdong Wang , Eric I-Chao Chang , Yan Xu

Intracerebral hemorrhage (ICH) is the most fatal subtype of stroke and is characterized by a high incidence of disability. Accurate segmentation of the ICH region and prognosis prediction are critically important for developing and refining…

Computer Vision and Pattern Recognition · Computer Science 2024-11-08 Xinlei Yu , Ahmed Elazab , Ruiquan Ge , Hui Jin , Xinchen Jiang , Gangyong Jia , Qing Wu , Qinglei Shi , Changmiao Wang

Alzheimer's disease (AD) and mild cognitive impairment (MCI) are associated with progressive gray matter loss, particularly in medial temporal structures. In this study, CAT12/SPM12 voxel-based morphometry was applied to baseline…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Trishna Niraula

The claustrum is a thin gray matter structure in each brain hemisphere, characterized by exceptionally high connectivity with nearly all brain regions. Despite extensive animal studies on its anatomy and function and growing evidence of…

Neurons and Cognition · Quantitative Biology 2025-05-16 Steven Seung-Suk Kang , Joseph Bodenheimer , Kayley Morris , Tracey Butler

Open-vocabulary image segmentation aims to partition an image into semantic regions according to arbitrary text descriptions. However, complex visual scenes can be naturally decomposed into simpler parts and abstracted at multiple levels of…

Computer Vision and Pattern Recognition · Computer Science 2023-12-22 Xudong Wang , Shufan Li , Konstantinos Kallidromitis , Yusuke Kato , Kazuki Kozuka , Trevor Darrell