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The effectiveness of data-driven techniques heavily depends on the input signal used to generate the estimation data. However, a significant research gap exists in the field of input design for nonlinear dynamic system identification. In…

Systems and Control · Electrical Eng. & Systems 2025-08-05 Max Herkersdorf , Oliver Nelles

Dimension reduction is often the first step in statistical modeling or prediction of multivariate spatial data. However, most existing dimension reduction techniques do not account for the spatial correlation between observations and do not…

Methodology · Statistics 2025-05-27 Si Cheng , Magali N. Blanco , Timothy V. Larson , Lianne Sheppard , Adam Szpiro , Ali Shojaie

Monte Carlo (MC) is generally considered as the most accurate dose calculation tool for particle therapy. However, a proper description of the beam particles kinematics is a necessary input for a realistic simulation. Such a description can…

In the current competitive environment, it is crucial for manufacturers to make the best decisions in the shortest time, in order to optimize the efficiency and effectiveness of the manufacturing systems. These decisions reach from the…

Artificial Intelligence · Computer Science 2020-06-16 Fadwa Oukhay , Pascale Zaraté , Taieb Romdhane

The paper is devoted to the geometrical calibration of industrial robots employed in precise manufacturing. To identify geometric parameters, an advanced calibration technique is proposed that is based on the non-linear experiment design…

Robotics · Computer Science 2012-11-29 Alexandr Klimchik , Anatol Pashkevich , Yier Wu , Benoît Furet , Stéphane Caro

Algorithms for machine learning-guided design, or design algorithms, use machine learning-based predictions to propose novel objects with desired property values. Given a new design task -- for example, to design novel proteins with high…

Machine Learning · Computer Science 2025-07-04 Clara Fannjiang , Ji Won Park

Small area estimation methods are used in surveys, where sample sizes are too small to get reliable direct estimates of parameters in some population domains. We consider design-based linear combinations of direct and synthetic estimators…

Methodology · Statistics 2023-12-22 Andrius Čiginas

We consider design issues for toxicology studies when we have a continuous response and the true mean response is only known to be a member of a class of nested models. This class of non-linear models was proposed by toxicologists who were…

Statistics Theory · Mathematics 2010-11-29 Holger Dette , Andrey Pepelyshev , Piter Shpilev , Weng Kee Wong

The US Food and Drug Administration launched Project Optimus with the aim of shifting the paradigm of dose-finding and selection towards identifying the optimal biological dose that offers the best balance between benefit and risk, rather…

Methodology · Statistics 2023-09-13 Ying Yuan , Heng Zhou , Suyu Liu

Attaining the optimal scale size of production systems is an issue frequently found in the priority questions on management agendas of various types of organizations. Determining the most productive scale size (MPSS) allows the decision…

General Economics · Economics 2019-10-11 Saeed Assani , Jianlin Jiang , Ahmad Assani , Feng Yang

Unsupervised dimension selection is an important problem that seeks to reduce dimensionality of data, while preserving the most useful characteristics. While dimensionality reduction is commonly utilized to construct low-dimensional…

Machine Learning · Statistics 2018-11-01 Jayaraman J. Thiagarajan , Rushil Anirudh , Rahul Sridhar , Peer-Timo Bremer

Industrial process control systems try to keep an output variable within a given tolerance around a target value. PID control systems have been widely used in industry to control input variables in order to reach this goal. However, this…

Machine Learning · Computer Science 2019-04-05 Noelia Oses , Aritz Legarretaetxebarria , Marco Quartulli , Igor García , Mikel Serrano

High-dimensional linear regression is important in many scientific fields. This article considers discrete measured data of underlying smooth latent processes, as is often obtained from chemical or biological systems. Interpretation in high…

The development of mechanistic models of biological systems is a central part of Systems Biology. One major task in developing these models is the inference of the correct model parameters. Due to the size of most realistic models and their…

Quantitative Methods · Quantitative Biology 2016-06-28 Jan Mikelson , Mustafa Khammash

This paper details how to parameterize the posterior distribution of state-space systems to generate improved optimization problems for system identification using variational inference. Three different parameterizations of the assumed…

Applications · Statistics 2025-01-15 Dimas Abreu Archanjo Dutra

Determinantal point processes (DPPs) offer a powerful approach to modeling diversity in many applications where the goal is to select a diverse subset. We study the problem of learning the parameters (the kernel matrix) of a DPP from…

Machine Learning · Statistics 2014-11-10 Boqing Gong , Wei-lun Chao , Kristen Grauman , Fei Sha

Although the Poisson point process (PPP) has been widely used to model base station (BS) locations in cellular networks, it is an idealized model that neglects the spatial correlation among BSs. The present paper proposes the use of…

Information Theory · Computer Science 2014-12-08 Yingzhe Li , François Baccelli , Harpreet S. Dhillon , Jeffrey G. Andrews

Optimum experimental design theory has recently been extended for parameter estimation in copula models. However, the choice of the correct dependence structure still requires wider analyses. In this work the issue of copula selection is…

Methodology · Statistics 2016-01-29 Elisa Perrone , Andreas Rappold , Werner G. Müller

This paper presents a comprehensive investigation into the decay mechanisms inherent in linear complexity sequence models. We systematically delineate the design space of decay mechanisms across four pivotal dimensions: parameterization…

Computation and Language · Computer Science 2025-09-08 Zhen Qin , Xuyang Shen , Yiran Zhong

Currently, the field of structure-based drug design is dominated by three main types of algorithms: search-based algorithms, deep generative models, and reinforcement learning. While existing works have typically focused on comparing models…

Machine Learning · Computer Science 2026-01-22 Kangyu Zheng , Kai Zhang , Jiale Tan , Xuehan Chen , Yingzhou Lu , Zaixi Zhang , Lichao Sun , Marinka Zitnik , Tianfan Fu , Zhiding Liang
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