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Deep learning has emerged as a powerful artificial intelligence tool to interpret medical images for a growing variety of applications. However, the paucity of medical imaging data with high-quality annotations that is necessary for…

Computer Vision and Pattern Recognition · Computer Science 2018-10-02 Faisal Mahmood , Richard Chen , Sandra Sudarsky , Daphne Yu , Nicholas J. Durr

Computed tomography (CT) is critical for various clinical applications, e.g., radiotherapy treatment planning and also PET attenuation correction. However, CT exposes radiation during acquisition, which may cause side effects to patients.…

Computer Vision and Pattern Recognition · Computer Science 2016-12-19 Dong Nie , Roger Trullo , Caroline Petitjean , Su Ruan , Dinggang Shen

Deep learning and data-driven approaches have shown great potential in scientific domains. The promise of data-driven techniques relies on the availability of a large volume of high-quality training datasets. Due to the high cost of…

Machine Learning · Computer Science 2022-02-08 Yuxin Yang , Xitong Zhang , Qiang Guan , Youzuo Lin

Purpose: To evaluate a proposed method to reconstruct CT numbers that accurately mimic conventional CT numbers from spectral CT data, as would have been produced by a conventional system without effects of beam hardening. Approach: We…

Medical Physics · Physics 2022-08-10 Fredrik Grönberg , Hans Bornefalk

One of the key impediments for developing and assessing robust medical imaging algorithms is limited access to large-scale datasets with suitable annotations. Synthetic data generated with plausible physical and biological constraints may…

Computer Vision and Pattern Recognition · Computer Science 2025-09-19 Christopher Wiedeman , Anastasiia Sarmakeeva , Elena Sizikova , Daniil Filienko , Miguel Lago , Jana G. Delfino , Aldo Badano

Purpose: This study assessed the dosimetric accuracy of synthetic CT images generated from magnetic resonance imaging (MRI) data for focal brain radiation therapy, using a deep learning approach. Material and Methods: We conducted a study…

A neural-network (NN)-based method for high-speed, high-definition dynamic optical coherence tomography (DOCT) using full-field swept-source optical coherence microscopy (FF-SS-OCM) is demonstrated. FF-SS-OCM provides high-definition OCT…

Medical imaging plays a vital role in modern diagnostics and treatment. The temporal nature of disease or treatment progression often results in longitudinal data. Due to the cost and potential harm, acquiring large medical datasets…

Computer Vision and Pattern Recognition · Computer Science 2023-01-16 Julian Schön , Raghavendra Selvan , Lotte Nygård , Ivan Richter Vogelius , Jens Petersen

Human anatomy, morphology, and associated diseases can be studied using medical imaging data. However, access to medical imaging data is restricted by governance and privacy concerns, data ownership, and the cost of acquisition, thus…

Purpose: Medical imaging has become increasingly important in diagnosing and treating oncological patients, particularly in radiotherapy. Recent advances in synthetic computed tomography (sCT) generation have increased interest in public…

Computed Tomography (CT) is widely used in healthcare for detailed imaging. However, Low-dose CT, despite reducing radiation exposure, often results in images with compromised quality due to increased noise. Traditional methods, including…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Herman Verinaz-Jadan , Su Yan

A key challenge for the development and deployment of artificial intelligence (AI) solutions in radiology is solving the associated data limitations. Obtaining sufficient and representative patient datasets with appropriate annotations may…

Image and Video Processing · Electrical Eng. & Systems 2024-07-03 Elena Sizikova , Andreu Badal , Jana G. Delfino , Miguel Lago , Brandon Nelson , Niloufar Saharkhiz , Berkman Sahiner , Ghada Zamzmi , Aldo Badano

Acquiring large quantities of data and annotations is known to be effective for developing high-performing deep learning models, but is difficult and expensive to do in the healthcare context. Adding synthetic training data using generative…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Menghan Yu , Sourabh Kulhare , Courosh Mehanian , Charles B Delahunt , Daniel E Shea , Zohreh Laverriere , Ishan Shah , Matthew P Horning

Synchrotron-based X-ray computed tomography is widely used for investigating inner structures of specimens at high spatial resolutions. However, potential beam damage to samples often limits the X-ray exposure during tomography experiments.…

Image and Video Processing · Electrical Eng. & Systems 2020-09-30 Ziling Wu , Tekin Bicer , Zhengchun Liu , Vincent De Andrade , Yunhui Zhu , Ian T. Foster

Positron Emission Tomography (PET) imaging requires accurate attenuation correction (AC) to account for photon loss due to tissue density variations. In PET/MR systems, computed tomography (CT), which offers a straightforward estimation of…

Image and Video Processing · Electrical Eng. & Systems 2025-04-11 Weijie Chen , James Wang , Alan McMillan

Recently, deep learning (DL) found its way to interventional X-ray skin dose estimation. While its performance was found to be acceptable, even more accurate results could be achieved if more data sets were available for training. One…

Volumetric rendering of Computed Tomography (CT) scans is crucial for visualizing complex 3D anatomical structures in medical imaging. Current high-fidelity approaches, especially neural rendering techniques, require time-consuming…

Computer Vision and Pattern Recognition · Computer Science 2025-05-26 Zhongpai Gao , Meng Zheng , Benjamin Planche , Anwesa Choudhuri , Terrence Chen , Ziyan Wu

In medical imaging analysis, deep learning has shown promising results. We frequently rely on volumetric data to segment medical images, necessitating the use of 3D architectures, which are commended for their capacity to capture interslice…

Image and Video Processing · Electrical Eng. & Systems 2023-05-18 Ikboljon Sobirov , Numan Saeed , Mohammad Yaqub

Volumetric, multimodal imaging with precise spatial and temporal co-registration can provide valuable and complementary information for diagnosis and monitoring. Considerable research has sought to combine 3D photoacoustic (PA) and…

X-ray Computed Tomography (CT) is an important tool in medical imaging to obtain a direct visualization of patient anatomy. However, the x-ray radiation exposure leads to the concern of lifetime cancer risk. Low-dose CT scan can reduce the…

Medical Physics · Physics 2018-10-30 Guoyang Ma , Chenyang Shen , Xun Jia