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Detailed modeling and simulation of biochemical systems is complicated by the problem of combinatorial complexity, an explosion in the number of species and reactions due to myriad protein-protein interactions and post-translational…

Quantitative Methods · Quantitative Biology 2014-05-20 Justin S. Hogg , Leonard A. Harris , Lori J. Stover , Niketh S. Nair , James R. Faeder

Quorum systems are a powerful mechanism for ensuring the consistency of replicated data. Production systems usually opt for majority quorums due to their simplicity and fault tolerance, but majority quorum systems provide poor throughput…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-04-12 Michael Whittaker , Aleksey Charapko , Joseph M. Hellerstein , Heidi Howard , Ion Stoica

The high-performance computing (HPC) community has recently seen a substantial diversification of hardware platforms and their associated programming models. From traditional multicore processors to highly specialized accelerators, vendors…

Plasma Physics · Physics 2024-11-11 Josef Ruzicka , Christian Asch , Esteban Meneses , Markus Rampp , Erwin Laure

We introduce Proceduray, an engine for real-time ray tracing of procedural geometry. Its motivation is the current lack of mid-level abstraction tools for scenes with primitives involving intersection shaders. Those scenes impose strict…

Graphics · Computer Science 2021-05-24 Vinícius da Silva , Tiago Novello , Hélio Lopes , Luiz Velho

We present a simple yet general and efficient approach to representation of computational meshes. Meshes are represented as sets of mesh entities of different topological dimensions and their incidence relations. We discuss a…

Numerical Analysis · Mathematics 2012-05-15 Anders Logg

Our current understanding of the structure and dynamics of aqueous interfaces at the molecular level has grown substantially in the last few decades due to the continuous development of surface-specific spectroscopies, such as vibrational…

Chemical Physics · Physics 2023-09-27 Yair Litman , Jinggang Lan , Yuki Nagata , David M. Wilkins

Molecular-scale interactions between solvated macromolecules and solid surfaces govern a large number of processes, from biology to engineering. Yet, despite extensive characterization at the macroscopic level, our molecular understanding…

Soft Condensed Matter · Physics 2026-05-07 Malo Velay , Jean Comtet

Molecule synthesis through machine learning is one of the fundamental problems in drug discovery. Current data-driven strategies employ one-step retrosynthesis models and search algorithms to predict synthetic routes in a top-bottom manner.…

Machine Learning · Computer Science 2024-06-05 Songtao Liu , Hanjun Dai , Yue Zhao , Peng Liu

An uncoupled multi-scale homogenization approach is used to estimate the effective thermal conductivities of plain weave C/C composites with a high degree of porosity. The geometrical complexity of the material system on individual scales…

Materials Science · Physics 2008-07-23 Blanka Tomkova , Michal Sejnoha , Jan Novak , Jan Zeman

The theory of interfacial properties in liquid-liquid or liquid-vapour systems is nearly 200 years old. The advent of computational tools has greatly advanced the field, mainly through the use of Molecular Dynamics simulations. Despite the…

Multivariate (MTV) porous materials exhibit unique structural complexities based on diverse spatial arrangements of multiple building block combinations. These materials possess potential synergistic functionalities that exceed the sum of…

Quantum Physics · Physics 2025-05-12 Shinyoung Kang , Younghun Kim , Jihan Kim

Traditional AI methods often rely on task-specific model designs and training, which constrain both the scalability of model size and generalization across different tasks. Here, we introduce ChemFM, a large foundation model specifically…

Computational Engineering, Finance, and Science · Computer Science 2025-11-06 Feiyang Cai , Katelin Zacour , Tianyu Zhu , Tzuen-Rong Tzeng , Yongping Duan , Ling Liu , Srikanth Pilla , Gang Li , Feng Luo

Scaling up hardware systems has become an important tactic for improving performance as Moore's law fades. Unfortunately, simulations of large hardware systems are often a design bottleneck due to slow throughput and long build times. In…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-07-31 Steven Herbst , Noah Moroze , Edgar Iglesias , Andreas Olofsson

A methodology is presented for estimating average values for the temperature and the frictional traction over a tool-workpiece interface using measured values of force and torque applied to the tool. The approach was developed specifically…

Materials Science · Physics 2014-04-01 Paul R. Dawson , Donald E. Boyce

We revisit the sharp-interface continuum thermodynamics of two-phase multicomponent fluid systems, accounting for partial mass and partial momentum balances both in the bulk phases and on the interface. This allows to describe the transfer…

Fluid Dynamics · Physics 2025-02-21 Dieter Bothe

The interfacial structures and interactions of two-dimensional (2D) materials on solid substrates are of fundamental importance for the fabrication and application of 2D materials. However, selection of a suitable solid substrate to grow 2D…

Materials Science · Physics 2021-06-16 Xian-Li Zhang , Jinbo Pan , Xin Jin , Yan-Fang Zhang , Jia-Tao Sun , Yu-Yang Zhang , Shixuan Du

Many devices, including touchscreens and robotic hands, involve frictional contacts. Optimizing these devices requires fine control of the interface's friction law. We lack systematic methods to create dry contact interfaces whose…

Soft Condensed Matter · Physics 2024-02-20 Antoine Aymard , Emilie Delplanque , Davy Dalmas , Julien Scheibert

Molecules adsorbing on metal surfaces form a variety of different surface polymorphs. How strongly this polymorphism affects interface properties is a priori unknown. In this work we investigate how strongly the surface polymorphism…

Materials Science · Physics 2022-03-14 Andreas Jeindl , Lukas Hörmann , Oliver T. Hofmann

Modern software development demands code that is maintainable, testable, and scalable by organizing the implementation into modular components with iterative reuse of existing codes. We formalize this iterative, multi-turn paradigm as…

Software Engineering · Computer Science 2026-04-16 Sizhe Wang , Zhengren Wang , Dongsheng Ma , Yongan Yu , Rui Ling , Zhiyu Li , Feiyu Xiong , Wentao Zhang

Identify, Transform, Benchmark, Show Quantum Advantage (ITBQ): Evaluating use cases for quantum computers. We introduce a four-step framework for assessing quantum computing applications -- from identifying relevant industry problems to…

Quantum Physics · Physics 2025-10-07 Michael Marthaler , Peter Pinski , Vladimir Rybkin , Iris Schwenk , Pascal Stadler , Marina Walt
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