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The Superfacility model is designed to leverage HPC for experimental science. It is more than simply a model of connected experiment, network, and HPC facilities; it encompasses the full ecosystem of infrastructure, software, tools, and…

Off-policy evaluation (OPE) holds the promise of being able to leverage large, offline datasets for both evaluating and selecting complex policies for decision making. The ability to learn offline is particularly important in many…

We present EPITIME (EPidemic Integral models TIMe profile Explorer), a computational framework for the simulation of two classes of integral epidemic models: an age of infection model and an information dependent behavioural model. The…

Quantitative Methods · Quantitative Biology 2026-05-04 Bruno Buonomo , Eleonora Messina , Claudia Panico , Mario Pezzella , Gaetano Zanghirati

The COVID-19 (Coronavirus disease 2019) pandemic has become a major global threat to human health and well-being. Thus, the development of computer-aided detection (CAD) systems that are capable to accurately distinguish COVID-19 from other…

Data management can be a complex challenge in fields such as bioinformatics and health sciences, which continuously generate extensive heterogeneous datasets. In the context of collaborative global health initiatives, secure storage and…

Software Engineering · Computer Science 2026-05-20 Danilo Silva , Monika Moir , Cheryl Baxter , Tulio de Oliveira , Joicymara Xavier , Marcel Dunaiski

Coronavirus COVID-19 spreads through the population mostly based on social contact. To gauge the potential for widespread contagion, to cope with associated uncertainty and to inform its mitigation, more accurate and robust modelling is…

Many science advances have been possible thanks to the use of research software, which has become essential to advancing virtually every Science, Technology, Engineering and Mathematics (STEM) discipline and many non-STEM disciplines…

Software Engineering · Computer Science 2019-02-26 Daniel S. Katz , Patrick Aerts , Neil P. Chue Hong , Anshu Dubey , Sandra Gesing , Henry J. Neeman , David E. Pearah

Open science represents a transformative research approach essential for enhancing sustainability and impact. Data generation encompasses various methods, from automated processes to human-driven inputs, creating a rich and diverse…

Databases · Computer Science 2025-03-21 Payel Patra , Daniele Di Pompeo , Antinisca Di Marco

Many recent efforts have shown that in-network computing can benefit various datacenter applications. In this paper, we explore a relatively less-explored domain which we argue can benefit from in-network computing: scientific workloads in…

Networking and Internet Architecture · Computer Science 2020-09-08 Daehyeok Kim , Ankush Jain , Zaoxing Liu , George Amvrosiadis , Damian Hazen , Bradley Settlemyer , Vyas Sekar

Edge-cloud collaborative computing (ECCC) has emerged as a pivotal paradigm for addressing the computational demands of modern intelligent applications, integrating cloud resources with edge devices to enable efficient, low-latency…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-03-19 Jing Liu , Yao Du , Kun Yang , Jiaqi Wu , Yan Wang , Xiping Hu , Zehua Wang , Yang Liu , Peng Sun , Azzedine Boukerche , Victor C. M. Leung

COVID-19 has impacted nations differently based on their policy implementations. The effective policy requires taking into account public information and adaptability to new knowledge. Epidemiological models built to understand COVID-19…

Artificial Intelligence · Computer Science 2021-02-15 Kaushik Roy , Qi Zhang , Manas Gaur , Amit Sheth

Scientific workflows have become essential for orchestrating complex computational processes across distributed resources, managing large datasets, and ensuring reproducibility in modern research. The Workflows Community Summit 2025, held…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-02-06 Irene Bonati , Silvina Caino-Lores , Tainã Coleman , Sagar Dolas , Sandro Fiore , Venkatesh Kannan , Marco Verdicchio , Sean R. Wilkinson , Rafael Ferreira da Silva

The high-performance computing (HPC) community has adopted incentive structures to motivate reproducible research, with major conferences awarding badges to papers that meet reproducibility requirements. Yet, many papers do not meet such…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-09-01 Valérie Hayot-Sasson , Nathaniel Hudson , André Bauer , Maxime Gonthier , Ian Foster , Kyle Chard

Early outbreak data analysis is critical for informing about their potential impact and interventions. However, data obtained early in outbreaks are often sensitive and subject to strict privacy restrictions. Thus, federated analysis, which…

Applications · Statistics 2026-01-27 Simon Busch-Moreno , Moritz U. G. Kraemer

With the increasing prevalence of artificial intelligence (AI) in diverse science/engineering communities, AI models emerge on an unprecedented scale among various domains. However, given the complexity and diversity of the software and…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-12-14 Sixing Yu , Murali Emani , Chunhua Liao , Pei-Hung Lin , Tristan Vanderbruggen , Xipeng Shen , Ali Jannesari

Distributed infrastructures for computation and analytics are now evolving towards an interconnected ecosystem allowing complex scientific workflows to be executed across hybrid systems spanning from IoT Edge devices to Clouds, and…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-07-25 Daniel Rosendo , Kate Keahey , Alexandru Costan , Matthieu Simonin , Patrick Valduriez , Gabriel Antoniu

Scientific processes rely on software as an important tool for data acquisition, analysis, and discovery. Over the years sustainable software development practices have made progress in being considered as an integral component of research.…

Software Engineering · Computer Science 2023-12-21 Akash Dhruv , Anshu Dubey

The need for computational resources grows as computational algorithms gain popularity in different sectors of the scientific community. This search has stimulated the development of several cloud platforms that abstract the complexity of…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-01-18 Henrique C. T. Santos , Luciano S. de Souza , Jonathan H. A. de Carvalho , Tiago A. E. Ferreira

High-performance computing (HPC) has evolved over decades through multiple architectural transitions, from vector supercomputers to massively parallel CPU clusters and GPU-accelerated systems, continuously expanding the frontier of…

Quantum Physics · Physics 2026-04-23 Suman Raj , Siva Sai , Yogesh Simmhan , Kyle Chard , Rajkumar Buyya

We investigate adaptive strategies to robustly and optimally control the COVID-19 pandemic via social distancing measures based on the example of Germany. Our goal is to minimize the number of fatalities over the course of two years without…

Populations and Evolution · Quantitative Biology 2021-02-09 Johannes Köhler , Lukas Schwenkel , Anne Koch , Julian Berberich , Patricia Pauli , Frank Allgöwer
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