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Multimodal AI has demonstrated superior performance over unimodal approaches by leveraging diverse data sources for more comprehensive analysis. However, applying this effectiveness in healthcare is challenging due to the limited…

Computer Vision and Pattern Recognition · Computer Science 2024-07-12 Pranav Poudel , Prashant Shrestha , Sanskar Amgain , Yash Raj Shrestha , Prashnna Gyawali , Binod Bhattarai

Multimodal large language models (MLLMs) have shown remarkable potential in various domains, yet their application in the medical field is hindered by several challenges. General-purpose MLLMs often lack the specialized knowledge required…

Artificial Intelligence · Computer Science 2025-09-29 Guanghao Zhu , Zhitian Hou , Zeyu Liu , Zhijie Sang , Congkai Xie , Hongxia Yang

The continuous development of artificial intelligence (AI) theory has propelled this field to unprecedented heights, owing to the relentless efforts of scholars and researchers. In the medical realm, AI takes a pivotal role, leveraging…

Machine Learning · Computer Science 2024-12-04 Qiyang Sun , Alican Akman , Björn W. Schuller

Accurate prediction of clinical scores is critical for early detection and prognosis of Alzheimers disease (AD). While existing approaches primarily focus on forecasting the ADAS-Cog global score, they often overlook the predictive value of…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Nur Amirah Abd Hamid , Mohd Shahrizal Rusli , Muhammad Thaqif Iman Mohd Taufek , Mohd Ibrahim Shapiai , Daphne Teck Ching Lai

Vision-language models have become increasingly powerful for tasks that require an understanding of both visual and linguistic elements, bridging the gap between these modalities. In the context of multimodal clinical AI, there is a growing…

Computation and Language · Computer Science 2024-04-30 Masoud Monajatipoor , Zi-Yi Dou , Aichi Chien , Nanyun Peng , Kai-Wei Chang

Machine Learning (ML) has recently been demonstrated to rival expert-level human accuracy in prediction and detection tasks in a variety of domains, including medicine. Despite these impressive findings, however, a key barrier to the full…

Artificial Intelligence · Computer Science 2021-07-01 D. Fompeyrine , E. S. Vorm , N. Ricka , F. Rose , G. Pellegrin

Whole slide imaging (WSI) has transformed digital pathology by enabling computational analysis of gigapixel histopathology images. Recent foundation model advances have accelerated progress in computational pathology, facilitating joint…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Peihang Wu , Zehong Chen , Lijian Xu

Masked Autoencoder (MAE) has recently been shown to be effective in pre-training Vision Transformers (ViT) for natural image analysis. By reconstructing full images from partially masked inputs, a ViT encoder aggregates contextual…

Image and Video Processing · Electrical Eng. & Systems 2023-04-24 Lei Zhou , Huidong Liu , Joseph Bae , Junjun He , Dimitris Samaras , Prateek Prasanna

Multimodal foundation models hold significant potential for automating radiology report generation, thereby assisting clinicians in diagnosing cardiac diseases. However, generated reports often suffer from serious factual inaccuracy. In…

Computation and Language · Computer Science 2025-02-07 Liwen Sun , James Zhao , Megan Han , Chenyan Xiong

Visual impairment represents a major global health challenge, with multimodal imaging providing complementary information that is essential for accurate ophthalmic diagnosis. This comprehensive survey systematically reviews the latest…

Image and Video Processing · Electrical Eng. & Systems 2025-08-07 Xiaoling Luo , Ruli Zheng , Qiaojian Zheng , Zibo Du , Shuo Yang , Meidan Ding , Qihao Xu , Chengliang Liu , Linlin Shen

Clinical diagnostic workups typically follow a modality escalation pathway: after initial clinical evaluation, clinicians begin with routine structural imaging (e.g., MRI), selectively add sequences such as FLAIR or T2 to refine the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Guangqian Yang , Tong Ding , Wenlong Hou , Yue Xun , Ye Du , Qian Niu , Shujun Wang

Neuroimaging techniques including functional magnetic resonance imaging (fMRI) and electroencephalogram (EEG) have shown promise in detecting functional abnormalities in various brain disorders. However, existing studies often focus on a…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Xinxu Wei , Kanhao Zhao , Yong Jiao , Nancy B. Carlisle , Hua Xie , Gregory A. Fonzo , Yu Zhang

Alzheimer's disease (AD) progression follows a complex continuum from normal cognition (NC) through mild cognitive impairment (MCI) to dementia, yet most deep learning approaches oversimplify this into discrete classification tasks. This…

Image and Video Processing · Electrical Eng. & Systems 2025-08-05 Yufeng Jiang , Hexiao Ding , Hongzhao Chen , Jing Lan , Xinzhi Teng , Gerald W. Y. Cheng , Zongxi Li , Haoran Xie , Jung Sun Yoo , Jing Cai

Language models traditionally used for cross-domain generalization have recently demonstrated task-specific reasoning. However, their top-down training approach on general corpora is insufficient for acquiring abstractions needed for deep…

Computation and Language · Computer Science 2025-09-03 Bhishma Dedhia , Yuval Kansal , Niraj K. Jha

In neuroscience, understanding inter-individual differences has recently emerged as a major challenge, for which functional magnetic resonance imaging (fMRI) has proven invaluable. For this, neuroscientists rely on basic methods such as…

Computer Vision and Pattern Recognition · Computer Science 2020-04-07 Akrem Sellami , François-Xavier Dupé , Bastien Cagna , Hachem Kadri , Stéphane Ayache , Thierry Artières , Sylvain Takerkart

Explainable Artificial Intelligence (XAI) has been presented as the critical component for unlocking the potential of machine learning in mental health screening (MHS). However, a persistent lab-to-clinic gap remains. Current XAI…

Computation and Language · Computer Science 2025-10-17 Ratna Kandala , Akshata Kishore Moharir , Divya Arvinda Nayak

Healthcare and medicine are multimodal disciplines that deal with multimodal data for reasoning and diagnosing multiple diseases. Although some multimodal reasoning models have emerged for reasoning complex tasks in scientific domains,…

Artificial Intelligence · Computer Science 2025-09-16 Susanta Mitra

Current machine learning methods for medical image analysis primarily focus on developing models tailored for their specific tasks, utilizing data within their target domain. These specialized models tend to be data-hungry and often exhibit…

Image and Video Processing · Electrical Eng. & Systems 2024-07-08 Ece Ozkan , Xavier Boix

During the evolution of large models, performance evaluation is necessarily performed to assess their capabilities and ensure safety before practical application. However, current model evaluations mainly rely on specific tasks and…

Artificial Intelligence · Computer Science 2024-03-07 Youzhi Qu , Chen Wei , Penghui Du , Wenxin Che , Chi Zhang , Wanli Ouyang , Yatao Bian , Feiyang Xu , Bin Hu , Kai Du , Haiyan Wu , Jia Liu , Quanying Liu