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We developed a software pipeline for quality control (QC) of histopathology whole slide images (WSIs) that segments various regions, such as blurs of different levels, tissue regions, tissue folds, and pen marks. Given the necessity and…
Accurate classification of Whole Slide Images (WSIs) and Regions of Interest (ROIs) is a fundamental challenge in computational pathology. While mainstream approaches often adopt Multiple Instance Learning (MIL), they struggle to capture…
Semi-supervised domain adaptation (SSDA) is quite a challenging problem requiring methods to overcome both 1) overfitting towards poorly annotated data and 2) distribution shift across domains. Unfortunately, a simple combination of domain…
Learning Invariant Representations has been successfully applied for reconciling a source and a target domain for Unsupervised Domain Adaptation. By investigating the robustness of such methods under the prism of the cluster assumption, we…
Automatic segmentation of infection areas in computed tomography (CT) images has proven to be an effective diagnosis approach for COVID-19. However, due to the limited number of pixel-level annotated medical images, accurate segmentation…
Labelling tissue components in histology whole slide images (WSIs) is prohibitively labour-intensive: a single slide may contain tens of thousands of structures--cells, nuclei, and other morphologically distinct objects--each requiring…
Deep learning models achieve high accuracy in segmentation tasks among others, yet domain shift often degrades the models' performance, which can be critical in real-world scenarios where no target images are available. This paper proposes…
This paper presents a novel method for unsupervised segmentation of pathology images. Staging of lung cancer is a major factor of prognosis. Measuring the maximum dimensions of the invasive component in a pathology images is an essential…
Comprehensive semantic segmentation is one of the key components for robust scene understanding and a requirement to enable autonomous driving. Driven by large scale datasets, convolutional neural networks show impressive results on this…
Multiple instance learning is an ideal mode of analysis for histopathology data, where vast whole slide images are typically annotated with a single global label. In such cases, a whole slide image is modelled as a collection of tissue…
Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…
Objective: We develop a computer-aided diagnosis (CAD) system using deep learning approaches for lesion detection and classification on whole-slide images (WSIs) with breast cancer. The deep features being distinguishing in classification…
Deep learning frameworks allowed for a remarkable advancement in semantic segmentation, but the data hungry nature of convolutional networks has rapidly raised the demand for adaptation techniques able to transfer learned knowledge from…
Survival prediction, utilizing pathological images and genomic profiles, is increasingly important in cancer analysis and prognosis. Despite significant progress, precise survival analysis still faces two main challenges: (1) The massive…
Computational analysis of whole slide images (WSIs) has seen significant research progress in recent years, with applications ranging across important diagnostic and prognostic tasks such as survival or cancer subtype prediction. Many…
Automatic outlining of different tissue types in digitized histological specimen provides a basis for follow-up analyses and can potentially guide subsequent medical decisions. The immense size of whole-slide-images (WSI), however, poses a…
The recent prevalence of deep neural networks has lead semantic segmentation networks to achieve human-level performance in the medical field when sufficient training data is provided. Such networks however fail to generalize when tasked…
We propose a segmentation framework that uses deep neural networks and introduce two innovations. First, we describe a biophysics-based domain adaptation method. Second, we propose an automatic method to segment white and gray matter, and…
Training models dedicated to semantic segmentation requires a large amount of pixel-wise annotated data. Due to their costly nature, these annotations might not be available for the task at hand. To alleviate this problem, unsupervised…
Convolutional neural networks (CNNs) have led to significant improvements in the semantic segmentation of images. When source and target datasets come from different modalities, CNN performance suffers due to domain shift. In such cases…