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Pathology computing has dramatically improved pathologists' workflow and diagnostic decision-making processes. Although computer-aided diagnostic systems have shown considerable value in whole slide image (WSI) analysis, the problem of…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Yonghuang Wu , Xuan Xie , Xinyuan Niu , Chengqian Zhao , Jinhua Yu

Deep learning models usually require a large amount of labeled data to achieve satisfactory performance. In multimedia analysis, domain adaptation studies the problem of cross-domain knowledge transfer from a label rich source domain to a…

Computer Vision and Pattern Recognition · Computer Science 2021-09-10 Lei Zhu , Zhaojing Luo , Wei Wang , Meihui Zhang , Gang Chen , Kaiping Zheng

Histopathology whole slide images (WSIs) play a very important role in clinical studies and serve as the gold standard for many cancer diagnoses. However, generating automatic tools for processing WSIs is challenging due to their enormous…

Computer Vision and Pattern Recognition · Computer Science 2022-09-28 Jingwei Zhang , Xin Zhang , Ke Ma , Rajarsi Gupta , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

Machine learning techniques used in computer-aided medical image analysis usually suffer from the domain shift problem caused by different distributions between source/reference data and target data. As a promising solution, domain…

Computer Vision and Pattern Recognition · Computer Science 2021-10-26 Hao Guan , Mingxia Liu

Multiple instance learning (MIL) has emerged as a popular method for classifying histopathology whole slide images (WSIs). Existing approaches typically rely on frozen pre-trained models to extract instance features, neglecting the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-20 Yi Lin , Zhengjie Zhu , Kwang-Ting Cheng , Hao Chen

Unsupervised domain adaptation addresses the problem of classifying data in an unlabeled target domain, given labeled source domain data that share a common label space but follow a different distribution. Most of the recent methods take…

Computer Vision and Pattern Recognition · Computer Science 2023-02-24 Hui Tang , Yaowei Wang , Kui Jia

Unsupervised domain adaptation (UDA) has been vastly explored to alleviate domain shifts between source and target domains, by applying a well-performed model in an unlabeled target domain via supervision of a labeled source domain. Recent…

Computer Vision and Pattern Recognition · Computer Science 2022-09-27 Xiaofeng Liu , Fangxu Xing , Nadya Shusharina , Ruth Lim , C-C Jay Kuo , Georges El Fakhri , Jonghye Woo

Whole slide image (WSI) has been widely used to assist automated diagnosis under the deep learning fields. However, most previous works only discuss the SINGLE task setting which is not aligned with real clinical setting, where pathologists…

Computer Vision and Pattern Recognition · Computer Science 2023-03-31 Weiqin Zhao , Shujun Wang , Maximus Yeung , Tianye Niu , Lequan Yu

Convolutional neural networks, the state of the art for image segmentation, have been successfully applied to histology images by many computational researchers. However, the translatability of this technology to clinicians and biological…

Image and Video Processing · Electrical Eng. & Systems 2021-01-19 Brendon Lutnick , David Manthey , Pinaki Sarder

Automated whole slide image (WSI) tagging has become a growing demand due to the increasing volume and diversity of WSIs collected nowadays in histopathology. Various methods have been studied to classify WSIs with single tags but none of…

Computer Vision and Pattern Recognition · Computer Science 2019-07-05 Weijian Li , Viet-Duy Nguyen , Haofu Liao , Matt Wilder , Ke Cheng , Jiebo Luo

Whole Slide Image (WSI) classification with multiple instance learning (MIL) in digital pathology faces significant computational challenges. Current methods mostly rely on extensive self-supervised learning (SSL) for satisfactory…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Hossein Jafarinia , Alireza Alipanah , Danial Hamdi , Saeed Razavi , Nahal Mirzaie , Mohammad Hossein Rohban

Existing unsupervised domain adaptation methods based on adversarial learning have achieved good performance in several medical imaging tasks. However, these methods focus only on global distribution adaptation and ignore distribution…

Computer Vision and Pattern Recognition · Computer Science 2022-07-11 Wei Feng , Lin Wang , Lie Ju , Xin Zhao , Xin Wang , Xiaoyu Shi , Zongyuan Ge

Unsupervised domain adaptation aiming to learn a specific task for one domain using another domain data has emerged to address the labeling issue in supervised learning, especially because it is difficult to obtain massive amounts of…

Machine Learning · Computer Science 2019-03-13 Jaeyoon Yoo , Changhwa Park , Yongjun Hong , Sungroh Yoon

Whole slide imaging is fundamental to biomedical microscopy and computational pathology. Previously, learning representations for gigapixel-sized whole slide images (WSIs) has relied on multiple instance learning with weak labels, which do…

Computer Vision and Pattern Recognition · Computer Science 2024-05-27 Xinhai Hou , Cheng Jiang , Akhil Kondepudi , Yiwei Lyu , Asadur Chowdury , Honglak Lee , Todd C. Hollon

Unsupervised Domain Adaptation (UDA) aims to align the labeled source distribution with the unlabeled target distribution to obtain domain invariant predictive models. However, the application of well-known UDA approaches does not…

Computer Vision and Pattern Recognition · Computer Science 2021-11-11 Ankit Singh

Convolutional Neural Networks (CNN) are state-of-the-art models for many image classification tasks. However, to recognize cancer subtypes automatically, training a CNN on gigapixel resolution Whole Slide Tissue Images (WSI) is currently…

Computer Vision and Pattern Recognition · Computer Science 2016-03-10 Le Hou , Dimitris Samaras , Tahsin M. Kurc , Yi Gao , James E. Davis , Joel H. Saltz

Histopathology is critical for the diagnosis of many diseases, including cancer. These protocols typically require pathologists to manually evaluate slides under a microscope, which is time-consuming and subjective, leading to interest in…

Computer Vision and Pattern Recognition · Computer Science 2023-03-07 Kianoush Falahkheirkhah , Alex Lu , David Alvarez-Melis , Grace Huynh

Generalizing deep neural networks to new target domains is critical to their real-world utility. In practice, it may be feasible to get some target data labeled, but to be cost-effective it is desirable to select a maximally-informative…

Computer Vision and Pattern Recognition · Computer Science 2021-10-12 Viraj Prabhu , Arjun Chandrasekaran , Kate Saenko , Judy Hoffman

Accurate segmentation of retinal fluids in 3D Optical Coherence Tomography images is key for diagnosis and personalized treatment of eye diseases. While deep learning has been successful at this task, trained supervised models often fail…

Computer Vision and Pattern Recognition · Computer Science 2022-08-05 Alvaro Gomariz , Huanxiang Lu , Yun Yvonna Li , Thomas Albrecht , Andreas Maunz , Fethallah Benmansour , Alessandra M. Valcarcel , Jennifer Luu , Daniela Ferrara , Orcun Goksel

In many histopathology tasks, sample classification depends on morphological details in tissue or single cells that are only visible at the highest magnification. For a pathologist, this implies tedious zooming in and out, while for a…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Ario Sadafi , Nassir Navab , Carsten Marr