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Chromosome classification is an important but difficult and tedious task in karyotyping. Previous methods only classify manually segmented single chromosome, which is far from clinical practice. In this work, we propose a detection based…

Computer Vision and Pattern Recognition · Computer Science 2021-08-18 Chunlong Luo , Tianqi Yu , Yufan Luo , Manqing Wang , Fuhai Yu , Yinhao Li , Chan Tian , Jie Qiao , Li Xiao

Medical image segmentation plays an essential role in developing computer-assisted diagnosis and therapy systems, yet still faces many challenges. In the past few years, the popular encoder-decoder architectures based on CNNs (e.g., U-Net)…

Computer Vision and Pattern Recognition · Computer Science 2021-07-20 Guoping Xu , Xingrong Wu , Xuan Zhang , Xinwei He

Accurately tracking particles and determining their coordinate along the optical axis is a major challenge in optical microscopy, especially when extremely high precision is needed. In this study, we introduce a deep learning approach using…

Image and Video Processing · Electrical Eng. & Systems 2025-08-05 Andrey Alexandrov , Giovanni Acampora , Giovanni De Lellis , Antonia Di Crescenzo , Chiara Errico , Daria Morozova , Valeri Tioukov , Autilia Vittiello

Cancer results from a sequence of genetic and epigenetic changes which lead to a variety of abnormal phenotypes including increased proliferation and survival of somatic cells, and thus, to a selective advantage of pre-cancerous cells. The…

Populations and Evolution · Quantitative Biology 2011-12-05 Erik A. Martens , R. Kostadinov , Carlo C. Maley , Oskar Hallatschek

We developed a deep ensemble learning model with a radiomics spatial encoding execution for improved glioma segmentation accuracy using multi-parametric MRI (mp-MRI). This model was developed using 369 glioma patients with a 4-modality…

Quantitative Methods · Quantitative Biology 2023-03-21 Yang Chen , Zhenyu Yang , Jingtong Zhao , Justus Adamson , Yang Sheng , Fang-Fang Yin , Chunhao Wang

Powerful deep learning tools, such as convolutional neural networks (CNN), are able to learn the input-output relationships of large complicated systems directly from data. Encoder-decoder deep CNNs are able to extract features directly…

Machine Learning · Statistics 2021-06-08 Alexander Scheinker , Frederick Cropp , Sergio Paiagua , Daniele Filippetto

Survival analysis utilizing multiple longitudinal medical images plays a pivotal role in the early detection and prognosis of diseases by providing insight beyond single-image evaluations. However, current methodologies often inadequately…

Image and Video Processing · Electrical Eng. & Systems 2025-08-14 Bingfan Liu , Haolun Shi , Jiguo Cao

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer in which the tumor-vascular involvement greatly affects the resectability and, thus, overall survival of patients. However, current prognostic prediction methods fail to…

Image and Video Processing · Electrical Eng. & Systems 2023-09-14 Hexin Dong , Jiawen Yao , Yuxing Tang , Mingze Yuan , Yingda Xia , Jian Zhou , Hong Lu , Jingren Zhou , Bin Dong , Le Lu , Li Zhang , Zaiyi Liu , Yu Shi , Ling Zhang

Double-stranded DNA (dsDNA) has been established as an efficient medium for charge migration, bringing it to the forefront of the field of molecular electronics as well as biological research. The charge migration rate is controlled by the…

Soft Condensed Matter · Physics 2020-11-25 Abhishek Aggarwal , Vinayak , Saientan Bag , Chiranjib Bhattacharyya , Umesh V. Waghmare , Prabal K Maiti

This paper introduces a deep transformer network for estimating the relative 6D pose of a Unmanned Aerial Vehicle (UAV) with respect to a ship using monocular images. A synthetic dataset of ship images is created and annotated with 2D…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Maneesha Wickramasuriya , Taeyoung Lee , Murray Snyder

This paper proposes a method for accurately estimating the relative position between two nodes with unknown locations in a diffusion-based molecular communication environment. A specialized node structure is designed, combining a central…

Signal Processing · Electrical Eng. & Systems 2025-09-10 Sangjun Hwang , Chan-Byoung Chae

The nuclear morphology of eukaryotic cells is determined by the interplay between the lamina forming the nuclear skeleton, the chromatin inside the nucleus and the coupling with the cytoskeleton. Nuclear alterations are often associated…

This paper investigates the learning theory of Transformer networks for regression tasks on the compact Euclidean domain $[0,1]^d$ and $d$-dimensional compact Riemannian manifolds. We propose a novel constructive approximation framework for…

Machine Learning · Statistics 2026-05-12 Zhongjie Shi , Wenjing Liao

Multi-organ segmentation is a critical task in computer-aided diagnosis. While recent deep learning methods have achieved remarkable success in image segmentation, huge variations in organ size and shape challenge their effectiveness in…

Image and Video Processing · Electrical Eng. & Systems 2025-10-31 Xizhi Tian , Changjun Zhou , Yulin. Yang

Understanding non-genetic determinants of cell fate is critical for developing and improving cancer therapies, as genetically identical cells can exhibit divergent outcomes under the same treatment conditions. In this work, we present a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Florian Bürger , Martim Dias Gomes , Adrián E. Granada , Noémie Moreau , Katarzyna Bozek

Molecular dynamic simulations are important in computational physics, chemistry, material, and biology. Machine learning-based methods have shown strong abilities in predicting molecular energy and properties and are much faster than DFT…

Molecular Networks · Quantitative Biology 2023-02-03 Zheng Yuan , Yaoyun Zhang , Chuanqi Tan , Wei Wang , Fei Huang , Songfang Huang

Automatic learning algorithms for improving the image quality of diagnostic B-mode ultrasound (US) images have been gaining popularity in the recent past. In this work, a novel convolutional neural network (CNN) is trained using time of…

Signal Processing · Electrical Eng. & Systems 2021-08-18 Roshan P Mathews , Mahesh Raveendranatha Panicker

Learning from data has led to paradigm shifts in a multitude of disciplines, including web, text, and image search, speech recognition, as well as bioinformatics. Can machine learning enable similar breakthroughs in understanding quantum…

Segmentation of lymphoma lesions is challenging due to their varied sizes and locations in whole-body PET scans. This work presents a fully-automated segmentation technique using a multi-center dataset of diffuse large B-cell lymphoma…

Cell lineage decisions occur in three-dimensional spatial patterns that are difficult to identify by eye. There is an ongoing effort to replicate such patterns using mathematical modeling. One approach uses long ranging cell-cell…

Cell Behavior · Quantitative Biology 2022-12-21 Robin Dirk , Jonas L. Fischer , Simon Schardt , Markus J. Ankenbrand , Sabine C. Fischer