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Metabolomic based approaches have gained much attention in recent years due to their promising potential to deliver objective tools for assessment of food intake. In particular, multiple biomarkers have emerged for single foods. However,…

Methodology · Statistics 2021-05-10 Silvia D'Angelo , Lorraine Brennan , Isobel Claire Gormley

Compartmental equations are primary tools in disease spreading studies. Their predictions are accurate for large populations but disagree with empirical and simulated data for finite populations, where uncertainties become a relevant…

Populations and Evolution · Quantitative Biology 2018-07-18 GM Nakamura , ND Gomes , GC Cardoso , AS Martinez

Background Multiple sclerosis (MS) is a complex immune-mediated disease with no currently known cure. There is growing evidence to support the role of diet in reducing some of the symptoms and disease progression in MS, and we previously…

Other Quantitative Biology · Quantitative Biology 2024-04-23 RD Russell , J He , LJ Black , A Begley

Machine Learning (ML) models are widely employed to drive many modern data systems. While they are undeniably powerful tools, ML models often demonstrate imbalanced performance and unfair behaviors. The root of this problem often lies in…

Machine Learning · Computer Science 2023-08-10 Ke Yang , Alexandra Meliou

Human life expectancy has dramatically improved over the course of the last century. Although this reflects a global improvement in sanitation and medical care, this also implies that more people suffer from diseases that typically manifest…

Other Quantitative Biology · Quantitative Biology 2022-07-11 Alexis Rapin , Maroun Bou Sleiman , Johan Auwerx

We consider high-dimensional regression over subgroups of observations. Our work is motivated by biomedical problems, where disease subtypes, for example, may differ with respect to underlying regression models, but sample sizes at the…

Key role in the prevention of diet-related chronic diseases plays the balanced nutrition together with a proper diet. The conventional dietary assessment methods are time-consuming, expensive and prone to errors. New technology-based…

Computer Vision and Pattern Recognition · Computer Science 2018-06-28 Ya Lu , Dario Allegra , Marios Anthimopoulos , Filippo Stanco , Giovanni Maria Farinella , Stavroula Mougiakakou

Additive models form a widely popular class of regression models which represent the relation between covariates and response variables as the sum of low-dimensional transfer functions. Besides flexibility and accuracy, a key benefit of…

Machine Learning · Statistics 2015-05-20 Alhussein Fawzi , Mathieu Sinn , Pascal Frossard

Heterogeneity is a hallmark of complex diseases. Regression-based heterogeneity analysis, which is directly concerned with outcome-feature relationships, has led to a deeper understanding of disease biology. Such an analysis identifies the…

Methodology · Statistics 2022-11-29 Ziye Luo , Xinyue Yao , Yifan Sun , Xinyan Fan

Factor modeling is an essential tool for exploring intrinsic dependence structures among high-dimensional random variables. Much progress has been made for estimating the covariance matrix from a high-dimensional factor model. However, the…

Statistics Theory · Mathematics 2016-10-26 Quefeng Li , Guang Cheng , Jianqing Fan , Yuyan Wang

Along with the widespread adoption of high-dimensional data, traditional statistical methods face significant challenges in handling problems with high correlation of variables, heavy-tailed distribution, and coexistence of sparse and dense…

Methodology · Statistics 2025-08-04 Xiaoyang Wei , Yanlin Tang , Xu Guo , Meiling Hao , Yanmei Shi

Recent progresses in data-driven analysis methods, including network-based approaches, are revolutionizing many classical disciplines. These techniques can also be applied to food and nutrition, which must be studied to design healthy…

Physics and Society · Physics 2015-03-17 Seunghyeon Kim , Jaeyun Sung , Mathias Foo , Yong-Su Jin , Pan-Jun Kim

Severe infectious diseases such as the novel coronavirus (COVID-19) pose a huge threat to public health. Stringent control measures, such as school closures and stay-at-home orders, while having significant effects, also bring huge economic…

Machine Learning · Computer Science 2022-03-01 Runzhe Wan , Xinyu Zhang , Rui Song

We introduce Mediffusion -- a new method for semi-supervised learning with explainable classification based on a joint diffusion model. The medical imaging domain faces unique challenges due to scarce data labelling -- insufficient for…

Computer Vision and Pattern Recognition · Computer Science 2024-11-15 Joanna Kaleta , Paweł Skierś , Jan Dubiński , Przemysław Korzeniowski , Kamil Deja

Joint species distribution models are popular in ecology for modeling covariate effects on species occurrence, while characterizing cross-species dependence. Data consist of multivariate binary indicators of the occurrences of different…

Methodology · Statistics 2025-07-08 Federica Stolf , David B. Dunson

In data collection for predictive modeling, under-representation of certain groups, based on gender, race/ethnicity, or age, may yield less-accurate predictions for these groups. Recently, this issue of fairness in predictions has attracted…

Applications · Statistics 2022-02-25 Hyungrok Do , Shinjini Nandi , Preston Putzel , Padhraic Smyth , Judy Zhong

A novel functional additive model is proposed which is uniquely modified and constrained to model nonlinear interactions between a treatment indicator and a potentially large number of functional and/or scalar pretreatment covariates. The…

Methodology · Statistics 2021-01-26 Hyung Park , Eva Petkova , Thaddeus Tarpey , R. Todd Ogden

Propensity score weighting is a tool for causal inference to adjust for measured confounders. Survey data are often collected under complex sampling designs such as multistage cluster sampling, which presents challenges for propensity score…

Methodology · Statistics 2016-07-27 Shu Yang

Factor Analysis based on multivariate $t$ distribution ($t$fa) is a useful robust tool for extracting common factors on heavy-tailed or contaminated data. However, $t$fa is only applicable to vector data. When $t$fa is applied to matrix…

Machine Learning · Statistics 2024-01-05 Xuan Ma , Jianhua Zhao , Changchun Shang , Fen Jiang , Philip L. H. Yu

In recent years, ML algorithms have been shown to be useful for predicting diseases based on health data and posed a potential application area for these algorithms such as modeling of diseases. The majority of these applications employ…

Machine Learning · Computer Science 2024-12-24 Elham Musaaed , Nabil Hewahi , Abdulla Alasaadi
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