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Decision-making in military aviation Prognostics and Health Management (PHM) faces significant challenges due to the "curse of dimensionality" in large-scale fleet operations, combined with sparse feedback and stochastic mission profiles.…

Machine Learning · Computer Science 2026-04-09 Yong Si , Mingfei Lu , Jing Li , Yang Hu , Guijiang Li , Yueheng Song , Zhaokui Wang

Adaptive Mixed-Criticality (AMC) is a fixed-priority preemptive scheduling algorithm for mixed-criticality hard real-time systems. It dominates many other scheduling algorithms for mixed-criticality systems, but does so at the cost of…

Operating Systems · Computer Science 2024-11-04 Bruno Mendes , Pedro F. Souto , Pedro C. Diniz

In this paper, we develop a knowledge-assisted deep reinforcement learning (DRL) algorithm to design wireless schedulers in the fifth-generation (5G) cellular networks with time-sensitive traffic. Since the scheduling policy is a…

Signal Processing · Electrical Eng. & Systems 2021-02-04 Zhouyou Gu , Changyang She , Wibowo Hardjawana , Simon Lumb , David McKechnie , Todd Essery , Branka Vucetic

The widespread application of Artificial Intelligence (AI) techniques has significantly influenced the development of new therapeutic agents. These computational methods can be used to design and predict the properties of generated…

Neural and Evolutionary Computing · Computer Science 2024-08-21 Arthur Cerveira , Frederico Kremer , Darling de Andrade Lourenço , Ulisses B Corrêa

For self-scheduling cascaded hydropower (S-CHP) facilities, medium-term planning is a critical step that coordinates water availability over the medium-term horizon, providing water usage guidance for their short-term operations in…

Systems and Control · Electrical Eng. & Systems 2025-01-10 Xianbang Chen , Yikui Liu , Neng Fan , Lei Wu

Combinatorial medication recommendation(CMR) is a fundamental task of healthcare, which offers opportunities for clinical physicians to provide more precise prescriptions for patients with intricate health conditions, particularly in the…

Artificial Intelligence · Computer Science 2025-01-14 Jie Tan , Yu Rong , Kangfei Zhao , Tian Bian , Tingyang Xu , Junzhou Huang , Hong Cheng , Helen Meng

Deep Reinforcement Learning (DRL) algorithms are known to be data inefficient. One reason is that a DRL agent learns both the feature and the policy tabula rasa. Integrating prior knowledge into DRL algorithms is one way to improve learning…

Machine Learning · Computer Science 2019-04-05 Gabriel V. de la Cruz , Yunshu Du , Matthew E. Taylor

Reinforcement learning (RL) is a type of artificial intelligence for making optimal choices. In healthcare, researchers generally use offline RL (ORL), where models are trained and evaluated from retrospective observational data. To…

Machine Learning · Computer Science 2026-04-30 Thomas Frost , Hrisheekesh Vaidya , Steve Harris

In scheduling problems common in the industry and various real-world scenarios, responding in real-time to disruptive events is essential. Recent methods propose the use of deep reinforcement learning (DRL) to learn policies capable of…

Artificial Intelligence · Computer Science 2024-01-31 Imanol Echeverria , Maialen Murua , Roberto Santana

A critical challenge facing clinicians managing chronic disease interventions is sustaining long-run patient health given limited information and resources. Digital therapeutics (DTs) provide a cost-effective way to manage interventions at…

Machine Learning · Computer Science 2026-05-26 Eric Pulick , Stephanie Carpenter , Matthew Buman , Yonatan Mintz

We propose a general formulation for continuous treatment recommendation problems in settings with clinical survival data, which we call the Deep Survival Dose Response Function (DeepSDRF). That is, we consider the problem of learning the…

Machine Learning · Statistics 2023-09-27 Jie Zhu , Blanca Gallego

Classical portfolio optimization often requires forecasting asset returns and their corresponding variances in spite of the low signal-to-noise ratio provided in the financial markets. Modern deep reinforcement learning (DRL) offers a…

Portfolio Management · Quantitative Finance 2023-05-19 Alessio Brini , Daniele Tantari

Deep neuroevolution and deep reinforcement learning (deep RL) algorithms are two popular approaches to policy search. The former is widely applicable and rather stable, but suffers from low sample efficiency. By contrast, the latter is more…

Machine Learning · Computer Science 2019-02-12 Aloïs Pourchot , Olivier Sigaud

Imagine a patient in critical condition. What and when should be measured to forecast detrimental events, especially under the budget constraints? We answer this question by deep reinforcement learning (RL) that jointly minimizes the…

Machine Learning · Computer Science 2019-06-11 Chun-Hao Chang , Mingjie Mai , Anna Goldenberg

Efficient task scheduling in large-scale distributed systems presents significant challenges due to dynamic workloads, heterogeneous resources, and competing quality-of-service requirements. Traditional centralized approaches face…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-03-27 Daniel Benniah John

Process rewards have been widely used in deep reinforcement learning to improve training efficiency, reduce variance, and prevent reward hacking. In LLM reasoning, existing works also explore various solutions for learning effective process…

Machine Learning · Computer Science 2026-05-21 Xian Wu , Kaijie Zhu , Ying Zhang , Lun Wang , Wenbo Guo

Precision rehabilitation offers the promise of an evidence-based approach for optimizing individual rehabilitation to improve long-term functional outcomes. Emerging techniques, including those driven by artificial intelligence, are rapidly…

Quantitative Methods · Quantitative Biology 2024-11-07 R. James Cotton , Bryant A. Seamon , Richard L. Segal , Randal D. Davis , Amrita Sahu , Michelle M. McLeod , Pablo Celnik , Sharon L. Ramey

Clinical decision support requires not only correct answers but also clinically valid reasoning. We propose Differential Reasoning Learning (DRL), a framework that improves clinical agents by learning from reasoning discrepancies. From…

Artificial Intelligence · Computer Science 2026-02-11 Jinsong Liu , Yuhang Jiang , Ramayya Krishnan , Rema Padman , Yiye Zhang , Jiang Bian

The increasing demand for autonomous systems in complex and dynamic environments has driven significant research into intelligent path planning methodologies. For decades, graph-based search algorithms, linear programming techniques, and…

Precision oncology aims to prescribe the optimal cancer treatment to the right patients, maximizing therapeutic benefits. However, identifying patient subgroups that may benefit more from experimental cancer treatments based on randomized…

Methodology · Statistics 2026-01-06 Xingyu Li , Qing Liu , Tony Jiang , Hong Amy Xia , Peng Wei , Brian P. Hobbs