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Coronaviruses are membrane-enveloped, non-segmented positive-strand RNA viruses belonging to the Coronaviridae family. Various animal species, mainly mammalian and avian, are severely infected by various coronaviruses, causing serious…

Quantitative Methods · Quantitative Biology 2023-04-17 Sarwan Ali , Taslim Murad , Murray Patterson

COVID-19 pandemic, is still unknown and is an important open question. There are speculations that bats are a possible origin. Likewise, there are many closely related (corona-) viruses, such as SARS, which was found to be transmitted…

Genomics · Quantitative Biology 2022-01-10 Sarwan Ali , Babatunde Bello , Prakash Chourasia , Ria Thazhe Punathil , Yijing Zhou , Murray Patterson

The SARS-CoV-2 coronavirus is the cause of the COVID-19 disease in humans. Like many coronaviruses, it can adapt to different hosts and evolve into different lineages. It is well-known that the major SARS-CoV-2 lineages are characterized by…

Machine Learning · Computer Science 2022-11-23 Sarwan Ali

The amount of sequencing data for SARS-CoV-2 is several orders of magnitude larger than any virus. This will continue to grow geometrically for SARS-CoV-2, and other viruses, as many countries heavily finance genomic surveillance efforts.…

Genomics · Quantitative Biology 2023-04-10 Sarwan Ali , Prakash Chourasia , Zahra Tayebi , Babatunde Bello , Murray Patterson

The ICTV develops, refines and maintains a universal virus taxonomy; Order is the highest taxon in the branching hierarchy of recognised viral taxa. Historically, ICTV (sub)committees have classified viruses on the basis of morphological…

Genomics · Quantitative Biology 2018-09-12 T. Wang , M. Herbster , I. S. Mian

SARS-CoV-2 is an upper respiratory system RNA virus that has caused over 3 million deaths and infecting over 150 million worldwide as of May 2021. With thousands of strains sequenced to date, SARS-CoV-2 mutations pose significant challenges…

Quantitative Methods · Quantitative Biology 2021-11-15 Yanyi Ding , Zhiyi Kuang , Yuxin Pei , Jeff Tan , Ziyu Zhang , Joseph Konan

With the rapid spread of COVID-19 worldwide, viral genomic data is available in the order of millions of sequences on public databases such as GISAID. This Big Data creates a unique opportunity for analysis towards the research of effective…

Machine Learning · Computer Science 2022-10-14 Sarwan Ali , Babatunde Bello , Zahra Tayebi , Murray Patterson

The availability of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) virus data post-COVID has reached exponentially to an enormous magnitude, opening research doors to analyze its behavior. Various studies are conducted by…

Neural and Evolutionary Computing · Computer Science 2025-01-28 Taslim Murad , Prakash Chourasia , Sarwan Ali , Imdad Ullah Khan , Murray Patterson

The widespread availability of large amounts of genomic data on the SARS-CoV-2 virus, as a result of the COVID-19 pandemic, has created an opportunity for researchers to analyze the disease at a level of detail unlike any virus before it.…

Machine Learning · Computer Science 2021-10-20 Zahra Tayebi , Sarwan Ali , Murray Patterson

Early detection and characterization of coronavirus disease (COVID-19), caused by SARS-CoV-2, remain critical for effective clinical response and public-health planning. The global availability of large-scale viral sequence data presents…

Machine Learning · Computer Science 2025-12-12 Sarwan Ali , Taslim Murad

Coronaviruses are a class of virus responsible of the recent outbreak of Human Severe Acute Respiratory Syndrome. The molecular machinery behind the viral entry and thus infectivity is based on the formation of the complex of virus spike…

Biomolecules · Quantitative Biology 2020-03-12 Luisa Di Paola , Alessandro Giuliani

Identifying viral pathogens and characterizing their transmission is essential to developing effective public health measures in response to a pandemic. Phylogenetics, though currently the most popular tool used to characterize the likely…

Quantitative Methods · Quantitative Biology 2015-05-28 Anil Raj , Michael Dewar , Gustavo Palacios , Raul Rabadan , Chris H. Wiggins

With the rapid global spread of COVID-19, more and more data related to this virus is becoming available, including genomic sequence data. The total number of genomic sequences that are publicly available on platforms such as GISAID is…

Genomics · Quantitative Biology 2021-11-16 Sarwan Ali , Murray Patterson

With the rapid spread of the novel coronavirus (COVID-19) across the globe and its continuous mutation, it is of pivotal importance to design a system to identify different known (and unknown) variants of SARS-CoV-2. Identifying particular…

Quantitative Methods · Quantitative Biology 2021-10-13 Sarwan Ali , Bikram Sahoo , Naimat Ullah , Alexander Zelikovskiy , Murray Patterson , Imdadullah Khan

Recorded history shows the long coexistence of humans and animals, suggesting it began much earlier. Despite some beneficial interdependence, many animals carry viral diseases that can spread to humans. These diseases are known as zoonotic…

Machine Learning · Computer Science 2025-09-16 Azher Ahmed Efat , Farzana Islam , Annajiat Alim Rasel , Munima Haque

SARS-CoV-2, like any other virus, continues to mutate as it spreads, according to an evolutionary process. Unlike any other virus, the number of currently available sequences of SARS-CoV-2 in public databases such as GISAID is already…

Populations and Evolution · Quantitative Biology 2021-10-13 Sarwan Ali , Tamkanat-E-Ali , Muhammad Asad Khan , Imdadullah Khan , Murray Patterson

CovID-19 genetics analysis is critical to determine virus type,virus variant and evaluate vaccines. In this paper, SARS-Cov-2 RNA sequence analysis relative to region or territory is investigated. A uniform framework of sequence SVM model…

Quantitative Methods · Quantitative Biology 2021-01-12 Jingwei Liu

The devastating impact of the COVID-19 pandemic caused by SARS coronavirus 2 (SARS CoV 2) has raised important questions about viral origin, mechanisms of zoonotic transfer to humans, whether companion or commercial animals can act as…

Biomolecules · Quantitative Biology 2021-07-12 Sakshi Piplani , Puneet Kumar Singh , David A. Winkler , Nikolai Petrovsky

The COVID-19 pandemic is spreading rapidly around the world, causing countries to impose lockdowns and efforts to develop vaccines on a global scale. However, human-to-animal and animal-to-human transmission cannot be ignored, as severe…

Populations and Evolution · Quantitative Biology 2024-08-20 Zi Hian Tan , Kian Yan Yong , Jian-Jun Shu

Covid-19 infection, which spread to the whole world in December 2019 and is still active, caused more than 250 thousand deaths in the world today. Researches on this subject have been focused on analyzing the genetic structure of the virus,…

Machine Learning · Computer Science 2023-04-25 Selcuk Yazar
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