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The COVID-19 pandemic has had and continues to have major impacts on planned and ongoing clinical trials. Its effects on trial data create multiple potential statistical issues. The scale of impact is unprecedented, but when viewed…

The ongoing COVID-19 pandemic has brought science to the fore of the public discourse and considering the complexity of the issues involved, with it also the challenge of effective and informative science communication. A particularly…

Applications · Statistics 2022-02-21 Ognjen Arandjelovic

Several key metrics in public health convey the probability that a primary event will lead to a more serious secondary event in the future. These "severity rates" can change over the course of an epidemic in response to shifting conditions…

This paper investigates various ways in which a pandemic such as the novel coronavirus, could be predicted using different mathematical models. It also studies the various ways in which these models could be depicted using various…

General Economics · Economics 2021-02-16 Shailesh Bharati , Rahul Batra

Forecasting the effect of COVID-19 is essential to design policies that may prepare us to handle the pandemic. Many methods have already been proposed, particularly, to forecast reported cases and deaths at country-level and state-level.…

Populations and Evolution · Quantitative Biology 2020-07-14 Ajitesh Srivastava , Tianjian Xu , Viktor K. Prasanna

Emerging at the end of 2019, COVID-19 has become a public health threat to people worldwide. Apart from the deaths who tested positive for COVID-19, many others have died from causes indirectly related to COVID-19. Therefore, the COVID-19…

Applications · Statistics 2020-11-18 Han Lin Shang , Ruofan Xu

This work introduces a Bayesian smoothing approach for the joint graduation of mortality rates across multiple populations. In particular, dynamical linear models are used to induce smoothness across ages through structured dependence,…

Topological Data Analysis is a relatively new field of study that uses topological invariants to study the shape of data. We analyze a dataset provided by the Centers for Disease Control and Prevention (CDC) using persistent homology and…

Algebraic Topology · Mathematics 2025-10-20 Megan Fairchild , Matthew Lemoine

More than ever COVID-19 is putting pressure on health systems all around the world, especially in Brazil. In this study we propose an analytical approach based on statistics and machine learning that uses lab exam data coming from patients…

Machine Learning · Computer Science 2020-11-09 Vitor Bezzan , Cleber D. Rocco

Purpose: This paper proposes a methodology and a computational tool to study the COVID-19 pandemic throughout the world and to perform a trend analysis to assess its local dynamics. Methods: Mathematical functions are employed to describe…

Since the start of the still ongoing COVID-19 pandemic, there have been many modeling efforts to assess several issues of importance to public health. In this work, we review the theory behind some important mathematical models that have…

Populations and Evolution · Quantitative Biology 2022-01-06 Fernando Saldaña , Jorge X Velasco-Hernández

During the ongoing COVID-19 pandemic, mathematical models of epidemic spreading have emerged as powerful tools to produce valuable predictions of the evolution of the pandemic, helping public health authorities decide which intervention…

Dynamical Systems · Mathematics 2021-11-18 Lorenzo Zino , Ming Cao

Breaking a complex bio-social phenomenon (epidemic) into its components, considering the processes that determine its dynamics, formalizing the accepted hypotheses in mathematical equations, selecting appropriate experimental and…

Physics and Society · Physics 2020-06-16 A. V. Sokolov , L. A. Sokolova

Monitoring the evolution of the Covid19 pandemic constitutes a critical step in sanitary policy design. Yet, the assessment of the pandemic intensity within the pandemic period remains a challenging task because of the limited quality of…

Populations and Evolution · Quantitative Biology 2022-02-14 Patrice Abry , Gersende Fort , Barbara Pascal , Nelly Pustelnik

Scientific advice to the UK government throughout the COVID-19 pandemic has been informed by ensembles of epidemiological models provided by members of the Scientific Pandemic Influenza group on Modelling (SPI-M). Among other applications,…

Applications · Statistics 2021-08-13 D. S. Silk , V. E. Bowman , D. Semochkina , U. Dalrymple , D. C. Woods

The COVID-19 pandemic has highlighted the need to upgrade systems for infectious disease surveillance and forecasting and modeling of the spread of infection, both of which inform evidence-based public health guidance and policies. Here, we…

Pandemic outbreaks such as COVID-19 occur unexpectedly, and need immediate action due to their potential devastating consequences on global health. Point-of-care routine assessments such as electrocardiogram (ECG), can be used to develop…

Signal Processing · Electrical Eng. & Systems 2023-01-12 Weijie Sun , Sunil Vasu Kalmady , Nariman Sepehrvand , Luan Manh Chu , Zihan Wang , Amir Salimi , Abram Hindle , Russell Greiner , Padma Kaul

Accurate epidemic forecasting is critical for effective public health interventions. This study compares Bayesian and Frequentist estimation frameworks within deterministic compartmental epidemic models, focusing on nonlinear least squares…

Quantitative Methods · Quantitative Biology 2025-09-09 Hamed Karami , Ruiyan Luo , Pejman Sanaei , Gerardo Chowell

Understanding the characteristics of public attention and sentiment is an essential prerequisite for appropriate crisis management during adverse health events. This is even more crucial during a pandemic such as COVID-19, as primary…

Social and Information Networks · Computer Science 2020-11-03 Oguzhan Gencoglu , Mathias Gruber

Forecasting the short-term spread of an ongoing disease outbreak is a formidable challenge due to the complexity of contributing factors, some of which can be characterized through interlinked, multi-modality variables such as…

Machine Learning · Computer Science 2024-04-11 Hongru Du , Jianan Zhao , Yang Zhao , Shaochong Xu , Xihong Lin , Yiran Chen , Lauren M. Gardner , Hao Frank Yang