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3D neuron growth and neurodevelopmental disorders (NDDs) deterioration exhibit complex morphological transformations as neurites differentiate into axons and dendrites, forming intricate networks driven by tubulin concentrations and…

Medical Physics · Physics 2025-05-06 Kuanren Qian , Yongjie Jessica Zhang

Neurons exhibit complex geometry in their branched networks of neurites which is essential to the function of individual neuron but also brings challenges to transport a wide variety of essential materials throughout their neurite networks…

Computational Engineering, Finance, and Science · Computer Science 2021-03-17 Angran Li , Amir Barati Farimani , Yongjie Jessica Zhang

This paper examines three generic strategies for improving the performance of neuro-evolution techniques aimed at evolving convolutional neural networks (CNNs). These were implemented as part of the Evolutionary eXploration of Augmenting…

Neural and Evolutionary Computing · Computer Science 2018-11-21 Travis Desell

Neural Metamorphosis (NeuMeta) is a recent paradigm for generating neural networks of varying width and depth. Based on Implicit Neural Representation (INR), NeuMeta learns a continuous weight manifold, enabling the direct generation of…

Neural and Evolutionary Computing · Computer Science 2025-10-15 Thomas Sommariva , Simone Calderara , Angelo Porrello

Recent advances in high-resolution microscopy have allowed scientists to better understand the underlying brain connectivity. However, due to the limitation that biological specimens can only be imaged at a single timepoint, studying…

Machine Learning · Computer Science 2022-02-03 Saeed Boorboor , Shawn Mathew , Mala Ananth , David Talmage , Lorna W. Role , Arie E. Kaufman

Neurodevelopmental disorders (NDDs) have arisen as one of the most prevailing chronic diseases within the US. Often associated with severe adverse impacts on the formation of vital central and peripheral nervous systems during the…

Machine learning analysis of neuroimaging data can accurately predict chronological age in healthy people and deviations from healthy brain ageing have been associated with cognitive impairment and disease. Here we sought to further…

Brain age is the estimate of biological age derived from neuroimaging datasets using machine learning algorithms. Increasing \textit{brain age gap} characterized by an elevated brain age relative to the chronological age can reflect…

Machine Learning · Computer Science 2025-01-06 Saurabh Sihag , Gonzalo Mateos , Alejandro Ribeiro

Brain age is the estimate of biological age derived from neuroimaging datasets using machine learning algorithms. Increasing brain age with respect to chronological age can reflect increased vulnerability to neurodegeneration and cognitive…

Quantitative Methods · Quantitative Biology 2024-02-13 Saurabh Sihag , Gonzalo Mateos , Alejandro Ribeiro

The quintessential property of neuronal systems is their intensive patterns of selective synaptic connections. The current work describes a physics-based approach to neuronal shape modeling and synthesis and its consideration for the…

Neurons and Cognition · Quantitative Biology 2009-11-10 Luciano da Fontoura Costa , Regina Celia Coelho

Over one in three people are affected by neurodegenerative disorders. Neural stem cells, which are multipotent regenerative cells with the potential to differentiate into any of the neural cell types, have immense therapeutic potential for…

Image and Video Processing · Electrical Eng. & Systems 2024-09-27 Nidhi Parthasarathy , Chandra Suda , Anika Mittal , Ian Young Chen , Ananya Jalihal

Deep learning has excelled in image recognition tasks through neural networks inspired by the human brain. However, the necessity for large models to improve prediction accuracy introduces significant computational demands and extended…

Computer Vision and Pattern Recognition · Computer Science 2024-08-27 Taigo Sakai , Kazuhiro Hotta

Dementia is a neuropsychiatric brain disorder that usually occurs when one or more brain cells stop working partially or at all. Diagnosis of this disorder in the early phases of the disease is a vital task to rescue patients lives from bad…

Machine Learning · Computer Science 2022-09-13 Sinan Faouri , Mahmood AlBashayreh , Mohammad Azzeh

Given the wide success of convolutional neural networks (CNNs) applied to natural images, researchers have begun to apply them to neuroimaging data. To date, however, exploration of novel CNN architectures tailored to neuroimaging data has…

Computer Vision and Pattern Recognition · Computer Science 2018-08-15 Pascal Sturmfels , Saige Rutherford , Mike Angstadt , Mark Peterson , Chandra Sripada , Jenna Wiens

Neurodegenerative diseases, such as Alzheimer's or Parkinson's disease, show characteristic degradation of structural brain networks. This degradation eventually leads to changes in the network dynamics and degradation of cognitive…

Adaptation and Self-Organizing Systems · Physics 2020-09-21 Alain Goriely , Ellen Kuhl , Christian Bick

Myelination plays an important role in the neurological development of infant brain and MRI can visualize the myelination extension as T1 high and T2 low signal intensity at white matter. We tried to construct a convolutional neural network…

Primary tumors infrequently lead to demise of cancer patients; instead, mortality and a significant degree of morbidity result from the growth of secondary tumors in distant organs (metastasis). It is well-known that malignant tumors induce…

Tissues and Organs · Quantitative Biology 2015-10-09 Arianna Bianchi , Konstantinos Syrigos , Georgios Lolas

Insomnia affects a vast population of the world and can have a wide range of causes. Existing treatments for insomnia have been linked with many side effects like headaches, dizziness, etc. As such, there is a clear need for improved…

Signal Processing · Electrical Eng. & Systems 2025-07-22 Kevin Monteiro , Sam Nallaperuma-Herzberg , Martina Mason , Steve Niederer

Deep neural networks have been demonstrated impressive results in various cognitive tasks such as object detection and image classification. In order to execute large networks, Von Neumann computers store the large number of weight…

Neural and Evolutionary Computing · Computer Science 2015-08-06 Jaeyong Chung , Taehwan Shin , Yongshin Kang
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