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Nowadays, there is a growing interest in the field of magnetic particle spectroscopy (MPS)-based bioassays. MPS monitors the dynamic magnetic response of surface-functionalized magnetic nanoparticles (MNPs) upon excitation by an alternating…

Systems and Control · Electrical Eng. & Systems 2022-11-14 Vinit Kumar Chugh , Arturo di Girolamo , Venkatramana D. Krishna , Kai Wu , Maxim C-J Cheeran , Jian-Ping Wang

Magnetic nanoparticles (MNPs) have been extensively used as contrasts and tracers for bioimaging, heating sources for tumor therapy, carriers for controlled drug delivery, and labels for magnetic immunoassays. Here, we describe a MNP…

Applied Physics · Physics 2019-09-11 Kai Wu , Jinming Liu , Diqing Su , Renata Saha , Jian-Ping Wang

In recent years, magnetic particle spectroscopy (MPS) has become a highly sensitive and versatile sensing technique for quantitative bioassays. It relies on the dynamic magnetic responses of magnetic nanoparticles (MNPs) for the detection…

Magnetic particle spectroscopy (MPS), also called magnetization response spectroscopy, is a novel measurement tool derived from magnetic particle imaging (MPI). It can be interpreted as a zero-dimensional version of MPI scanner. MPS was…

Applied Physics · Physics 2020-03-24 Kai Wu , Diqing Su , Renata Saha , Jinming Liu , Vinit Kumar Chugh , Jian-Ping Wang

Magnetic particle spectroscopy (MPS) is a technology that derives from magnetic particle imaging (MPI) and thrives as a standalone platform for many biological and biomedical applications, benefiting from the facile preparation and chemical…

Applied Physics · Physics 2020-03-24 Kai Wu , Jinming Liu , Diqing Su , Renata Saha , Vinit Kumar Chugh , Jian-Ping Wang

This Letter is a micromagnetic simulation-based study on the GHz-frequency ferromagnetic resonances for the detection of magnetic nanoparticles (MNPs) using spin current nano-oscillator (SCNO) operating in precession mode as a spintronic…

Applied Physics · Physics 2019-10-01 Renata Saha , Kai Wu , Diqing Su , Jian-Ping Wang

We show that a single atomic magnetometer in a magnetically unshielded environment can be used to perform magnetic particle spectroscopy (MPS) and AC susceptometry (ACS) on liquid-suspended magnetic nanoparticles. We demonstrate methods…

Biological Physics · Physics 2016-12-22 Simone Colombo , Victor Lebedev , Zoran D. Grujic , Vladimir Dolgovskiy , Antoine Weis

Magnetic particle imaging (MPI) is an in-vivo imaging method to detect magnetic nanoparticles for blood vessel imaging and molecular target imaging. Compared with conventional molecular imaging devices (such as nuclear medicine imaging PET…

Medical Physics · Physics 2024-04-26 Guang Jia , Zhongwei Bian , Tianshu Li , Shi Bai , Chenxing Hu , Lixuan Zhao , Peng Gao , Tanping Li , Hui Hui , Jie Tian

Nanomechanical spectroscopy (NMS) is a recently developed approach to determine optical absorption spectra of nanoscale materials via mechanical measurements. It is based on measuring changes in the resonance frequency of a membrane…

In this paper, we present a new method for the magnetic characterization of bulk materials, microstructures, and nanostructures. We investigated the magnetic and morphological properties of two colloidal dispersions of iron oxide (Fe3O4)…

Magnetic nanoparticles (MNPs) play an important role in biomedical applications including imaging modalities such as MRI and magnetic particle imaging (MPI). The latter one exploits the non-linear magnetization response of a large ensemble…

Mesoscale and Nanoscale Physics · Physics 2021-10-27 Hannes Albers , Tobias Knopp , Martin Möddel , Marija Boberg , Tobias Kluth

Magnetic particle imaging (MPI) is a tracer-based medical imaging modality that enables quantification and spatial mapping of magnetic nanoparticle (MNP) distribution. The magnetization response of MNPs depends on experimental conditions…

Signal Processing · Electrical Eng. & Systems 2025-09-03 Asli Alpman , Mustafa Utkur , Emine Ulku Saritas

In this work, we report a 5-minute magnetic particle spectroscopy (MPS)-based bioassay strategy. In our approach, surface functionalized magnetic nanoparticles (MNPs) are incubated with target analytes at 37 {\deg}C with agitation for 3…

Magnetic nanoparticles (MNPs) with proper surface functionalization have been extensively applied as labels for magnetic immunoassays, carriers for controlled drug/gene delivery, tracers and contrasts for magnetic imaging, etc. Here, we…

We demonstrate the quantitative measurement of the magnetization of individual magnetic nanoparticles (MNP) using a magnetic force microscope (MFM). The quantitative measurement is realized by calibration of the MFM signal using an MNP…

Mesoscale and Nanoscale Physics · Physics 2010-02-22 Kai-Felix Braun , Sibylle Sievers , Dietmar Eberbeck , Stefan Gustafsson , Eva Olsson , Hans Werner Schumacher , Uwe Siegner

The experiments on the impact of the size of magnetite clusters on various magnetic properties (magnetic moment, Curie temperature, blocking temperature etc.) have been carried out. The methods of magnetic separation, centrifuging of water…

Materials Science · Physics 2015-12-24 V. N. Nikiforov , A. N. Ignatenko , A. V. Ivanov , V. Yu. Irkhin

One of the main challenges to overcome to perform nanomechanical Mass Spectrometry (NEMS-MS) analysis in a practical time frame stems from the size mismatch between the analyte beam and the extremely small nanomechanical detector area. We…

In this paper, a new concept of magnetic nanoparticles as magneto-optical markers is proposed, and a "magneto-optical gate" effect is explored. High-sensitivity detection of magnetic nanoparticles (MNPs) was developed based on this…

Applied Physics · Physics 2023-01-20 Xinchao Cui , Chong Lu , Chunping Liu , Wenzhong Liu

Current approaches to Mass Spectrometry (MS) require ionization of the analytes of interest. For high-mass species, the resulting charge state distribution can be complex and difficult to interpret correctly. In this article, using a setup…

Magnetic nanoparticles (MNPs) have excellent magnetic-temperature characteristic. However, current temperature measurement based on MNPs is interfered by concentration. Utilizing the electron spin resonance (ESR), we propose a highly…

Mesoscale and Nanoscale Physics · Physics 2021-08-25 Shuai Wang , Jing Zhong , Wenzhong Liu
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