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Multiple sclerosis is a chronic autoimmune disease that affects the central nervous system. Understanding multiple sclerosis progression and identifying the implicated brain structures is crucial for personalized treatment decisions.…

Melanoma diagnosed and treated in its early stages can increase the survival rate. A projected increase in skin cancer incidents and a dearth of dermatopathologists have emphasized the need for computational pathology (CPATH) systems. CPATH…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Neel Kanwal , Roger Amundsen , Helga Hardardottir , Luca Tomasetti , Erling Sandoy Undersrud , Emiel A. M. Janssen , Kjersti Engan

Accurate and efficient detection of ovarian cancer at early stages is critical to ensure proper treatments for patients. Among the first-line modalities investigated in studies of early diagnosis are features distilled from protein mass…

Machine Learning · Computer Science 2022-07-15 Dixon Vimalajeewa , Scott Alan Bruce , Brani Vidakovic

Medical imaging is a cornerstone of therapy and diagnosis in modern medicine. However, the choice of imaging modality for a particular theranostic task typically involves trade-offs between the feasibility of using a particular modality…

Computer Vision and Pattern Recognition · Computer Science 2022-07-22 Mayur Mallya , Ghassan Hamarneh

Diffuse Reflectance Spectroscopy has demonstrated a strong aptitude for identifying and differentiating biological tissues. However, the broadband and smooth nature of these signals require algorithmic processing, as they are often…

Image and Video Processing · Electrical Eng. & Systems 2025-03-06 Nicola Rossberg , Celina L. Li , Simone Innocente , Stefan Andersson-Engels , Katarzyna Komolibus , Barry O'Sullivan , Andrea Visentin

Computational pathology models that use digitized histopathology whole-slide images have the potential to become a cost-effective and scalable alternative to molecular assays for the prediction of genomic biomarkers, a key task in precision…

Quantitative Methods · Quantitative Biology 2026-03-03 Ekaterina Redekop , Eric Zimmermann , Ava P Amini , Alex X Lu , Neil Tenenholtz , James Brian Hall , Lorin Crawford , Kristen A Severson

Cervical cancer is a prevalent disease affecting millions of women worldwide every year. It requires significant attention, as early detection during the precancerous stage provides an opportunity for a cure. The screening and diagnosis of…

Image and Video Processing · Electrical Eng. & Systems 2023-10-26 Hana Ahmadzadeh Sarhangi , Dorsa Beigifard , Elahe Farmani , Hamidreza Bolhasani

In the current technological era, the medical profession has emerged as one of the researchers' favorite subject areas, and cancer is one of them. Because there is now no effective treatment for this illness, it is a matter of concern. Only…

Machine Learning · Computer Science 2024-10-23 Praneeth Kumar T , Nidhi Srivastava , Rakshith Mahishi , Chayadevi M L

Recent advances in multiplex imaging have enabled researchers to locate different types of cells within a tissue sample. This is especially relevant for tumor immunology, as clinical regimes corresponding to different stages of disease or…

Although cancer is known to be characterized by several unifying biological hallmarks, systems biology has had limited success in identifying molecular signatures present in in all types of cancer. The current availability of rich data sets…

Histopathological images are widely used for the analysis of diseased (tumor) tissues and patient treatment selection. While the majority of microscopy image processing was previously done manually by pathologists, recent advances in…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Andrey Ignatov , Josephine Yates , Valentina Boeva

Organ morphology is a key indicator for prostate disease diagnosis and prognosis. For instance, In longitudinal study of prostate cancer patients under active surveillance, the volume, boundary smoothness and their changes are closely…

Image and Video Processing · Electrical Eng. & Systems 2021-06-08 Qianye Yang , Tom Vercauteren , Yunguan Fu , Francesco Giganti , Nooshin Ghavami , Vasilis Stavrinides , Caroline Moore , Matt Clarkson , Dean Barratt , Yipeng Hu

Early detection is crucial for successful cancer treatment and increasing survivability rates, particularly in the most common forms. Ten different cancers have been identified in most of these advances that effectively use CNNs…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Hossein Molaeian , Kaveh Karamjani , Sina Teimouri , Saeed Roshani , Sobhan Roshani

Depolarization of circularly polarized light scattered from biological tissues depends on structural changes in cell nuclei, which can provide valuable information for differentiating cancer tissues concealed in healthy tissues. In this…

Medical Physics · Physics 2020-12-08 Nozomi Nishizawa , Bassam Al-Qadi , Takahiro Kuchimaru

Multiplexed immunofluorescence provides an unprecedented opportunity for studying specific cell-to-cell and cell microenvironment interactions. We employ graph neural networks to combine features obtained from tissue morphology with…

Accurate molecular subtype classification is essential for personalized breast cancer treatment, yet conventional immunohistochemical analysis relies on invasive biopsies and is prone to sampling bias. Although dynamic contrast-enhanced…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Sen Zeng , Hong Zhou , Zheng Zhu , Yang Liu

Hyperspectroscopy is a new method of surface image taking, providing simultaneously high position and spectral resolutions which allow one to make some conclusions about chemical compositions of the surfaces. We are now studying…

Instrumentation and Detectors · Physics 2016-11-18 I. Rodionov , J-M. Bidault , I. Crotty , P. Fonte , F. Galy , V. Peskov , O. Zanette

The gold standard for gastric cancer detection is gastric histopathological image analysis, but there are certain drawbacks in the existing histopathological detection and diagnosis. In this paper, based on the study of computer aided…

Image and Video Processing · Electrical Eng. & Systems 2022-05-18 Haiqing Zhang , Chen Li , Shiliang Ai , Haoyuan Chen , Yuchao Zheng , Yixin Li , Xiaoyan Li , Hongzan Sun , Xinyu Huang , Marcin Grzegorzek

Multifractal analysis has become a powerful signal processing tool that characterizes signals or images via the fluctuations of their pointwise regularity, quantified theoretically by the so-called multifractal spectrum. The practical…

Functional Analysis · Mathematics 2018-11-09 Roberto Leonarduzzi , Patrice Abry , Herwig Wendt , Stéphane Jaffard , Hugo Touchette

Hematoxylin and Eosin (H&E)-stained images are commonly used to detect nuclear or cancerous regions in cells from images captured by a microscope. Identifying cancer cytoplasm is crucial for determining the type of cancer; hence, obtaining…

Image and Video Processing · Electrical Eng. & Systems 2025-07-08 Rebeka Sultana , Hibiki Horibe , Tomoaki Murakami , Ikuko Shimizu