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In this study, Brillouin spectroscopy was employed to investigate the viscoelastic properties of melanoma cells in vitro. Using a custom-built confocal Brillouin microspectrometer, we obtained Brillouin shifts and full width at half maximum…

Breast cancer is one of the most common cancers in women worldwide, and early detection can significantly reduce the mortality rate of breast cancer. It is crucial to take multi-scale information of tissue structure into account in the…

Computer Vision and Pattern Recognition · Computer Science 2021-01-01 Mo Zhang , Quanzheng Li

This work presents the application of Multifractal Detrended Fluctuation Analysis for the surface electromyography signals obtained from the patients suffering from rectal cancer. The electrical activity of an external anal sphincter at…

Medical Physics · Physics 2017-09-20 Paulina Trybek , Michal Nowakowski , Lukasz Machura

Accurate diagnosis of breast cancer in histopathology images is challenging due to the heterogeneity of cancer cell growth as well as of a variety of benign breast tissue proliferative lesions. In this paper, we propose a practical and…

Computer Vision and Pattern Recognition · Computer Science 2020-05-06 Xingyu Li , Marko Radulovic , Ksenija Kanjer , Konstantinos N. Plataniotis

Cancer research is increasingly driven by the integration of diverse data modalities, spanning from genomics and proteomics to imaging and clinical factors. However, extracting actionable insights from these vast and heterogeneous datasets…

Breast cancer is a disease that threatens many women's life, thus, early and accurate detection plays a key role in reducing the mortality rate. Mammography stands as the reference technique for breast cancer screening; nevertheless, many…

Image and Video Processing · Electrical Eng. & Systems 2022-02-09 Juan Zuluaga-Gomez , N. Zerhouni , Z. Al Masry , C. Devalland , C. Varnier

Breast cancers is the second leading cause of cancer mortality in women; early diagnosis increase the probability of a successful therapy; any marginal improvement in this direction helps sparing lives. In this context functional imaging…

Instrumentation and Detectors · Physics 2019-05-02 Adriana Marcucci , Franco Garibaldi , Giulia Limiti , Teresa Insero , Paolo Musico , Evaristo Cisbani

Early detection and prognosis of breast cancer are feasible by utilizing histopathological grading of biopsy specimens. This research is focused on detection and grading of nuclear pleomorphism in histopathological images of breast cancer.…

Computer Vision and Pattern Recognition · Computer Science 2016-12-06 Pegah Faridi , Habibollah Danyali , Mohammad Sadegh Helfroush , Mojgan Akbarzadeh Jahromi

Histopathological imaging is vital for cancer research and clinical practice, with multiplexed Immunofluorescence (MxIF) and Hematoxylin and Eosin (H&E) providing complementary insights. However, aligning different stains at the cell level…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Jun Jiang , Raymond Moore , Brenna Novotny , Leo Liu , Zachary Fogarty , Ray Guo , Markovic Svetomir , Chen Wang

Breast cancer is in the most common malignant tumor in women. It accounted for 30% of new malignant tumor cases. Although the incidence of breast cancer remains high around the world, the mortality rate has been continuously reduced. This…

Image and Video Processing · Electrical Eng. & Systems 2022-02-01 Liuhua Zhang

We propose, analyze and realize a variational multiclass segmentation scheme that partitions a given image into multiple regions exhibiting specific properties. Our method determines multiple functions that encode the segmentation regions…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Nadja Gruber , Johannes Schwab , Sebastien Court , Elke Gizewski , Markus Haltmeier

Phase and polarisation of coherent light are highly perturbed by interaction with microstructural changes in pre-malignant tissue, holding promise for label-free early cancer detection in endoscopically accessible tissues such as the…

Cancer is one of the leading causes of death worldwide, making the development of rapid, minimally invasive, label-free and scalable diagnostic strategies a major challenge in modern oncology. In this context, spectroscopic liquid biopsy…

Tissues are fractal due to its self-similar structure, and the fractal dimension change with the abnormalities such as in disease like cancer. The optical imaging of thin slices of tissue using transmission microscopy can produce an…

Biological Physics · Physics 2020-12-29 Liam Elkington , Prakash Adhikari , Prabhakar Pradhan

We propose a polarimetric microwave imaging technique that exploits recent advances in computational imaging. We utilize a frequency-diverse cavity-backed metasurface, allowing us to demonstrate high-resolution polarimetric imaging using a…

Mammography screening for early detection of breast lesions currently suffers from high amounts of false positive findings, which result in unnecessary invasive biopsies. Diffusion-weighted MR images (DWI) can help to reduce many of these…

Three-dimensional imaging of biological cells is crucial for the investigation of cell biology, provide valuable information to reveal the mechanisms behind pathophysiology of cells and tissues. Recent advances in optical diffraction…

Biological Physics · Physics 2016-03-03 Kyoohyun Kim , Jonghee Yoon , Seungwoo Shin , SangYun Lee , Su-A Yang , YongKeun Park

Detecting early-stage ovarian cancer accurately and efficiently is crucial for timely treatment. Various methods for early diagnosis have been explored, including a focus on features derived from protein mass spectra, but these tend to…

Applications · Statistics 2024-01-30 Raymond J. Hinton , Jihyun Byun , Dixon Vimalajeewa , Brani Vidakovic

Images remain the largest data source in the field of healthcare. But at the same time, they are the most difficult to analyze. More than often, these images are analyzed by human experts such as pathologists and physicians. But due to…

Image and Video Processing · Electrical Eng. & Systems 2021-10-11 Dikshant Sagar

Medical image segmentation is particularly critical as a prerequisite for relevant quantitative analysis in the treatment of clinical diseases. For example, in clinical cervical cancer radiotherapy, after acquiring subabdominal MRI images,…

Image and Video Processing · Electrical Eng. & Systems 2023-06-30 Yu Xiao , Xin Yang , Sijuan Huang , Lihua Guo