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The Segment Anything Model (SAM) is a foundational model for image segmentation tasks, known for its strong generalization across diverse applications. However, its impressive performance comes with significant computational and resource…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Xiaorui Sun , Jun Liu , Heng Tao Shen , Xiaofeng Zhu , Ping Hu

Radiological images such as computed tomography (CT) and X-rays render anatomy with intrinsic structures. Being able to reliably locate the same anatomical structure across varying images is a fundamental task in medical image analysis. In…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Ke Yan , Jinzheng Cai , Dakai Jin , Shun Miao , Dazhou Guo , Adam P. Harrison , Youbao Tang , Jing Xiao , Jingjing Lu , Le Lu

Foundation models have taken over natural language processing and image generation domains due to the flexibility of prompting. With the recent introduction of the Segment Anything Model (SAM), this prompt-driven paradigm has entered image…

Image and Video Processing · Electrical Eng. & Systems 2023-04-13 Saikat Roy , Tassilo Wald , Gregor Koehler , Maximilian R. Rokuss , Nico Disch , Julius Holzschuh , David Zimmerer , Klaus H. Maier-Hein

The Segment Anything Model (SAM) is a foundation model for general image segmentation. Although it exhibits impressive performance predominantly on natural images, understanding its robustness against various image perturbations and domains…

Computer Vision and Pattern Recognition · Computer Science 2023-05-25 Yuqing Wang , Yun Zhao , Linda Petzold

In this paper, we address the challenge of image resolution variation for the Segment Anything Model (SAM). SAM, known for its zero-shot generalizability, exhibits a performance degradation when faced with datasets with varying image sizes.…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Yiran Song , Qianyu Zhou , Xiangtai Li , Deng-Ping Fan , Xuequan Lu , Lizhuang Ma

Segment Anything Model (SAM), a prompt-driven foundation model for natural image segmentation, has demonstrated impressive zero-shot performance. However, SAM does not work when directly applied to medical image segmentation, since SAM…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Bin Xie , Hao Tang , Bin Duan , Dawen Cai , Yan Yan , Gady Agam

Segmentation of anatomical structures and pathological regions in medical images is essential for modern clinical diagnosis, disease research, and treatment planning. While significant advancements have been made in deep learning-based…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Taha Koleilat , Hojat Asgariandehkordi , Hassan Rivaz , Yiming Xiao

We explore the feasibility and potential of building a ground-truth-free evaluation model to assess the quality of segmentations generated by the Segment Anything Model (SAM) and its variants in medical imaging. This evaluation model…

Image and Video Processing · Electrical Eng. & Systems 2024-09-25 Ahjol Senbi , Tianyu Huang , Fei Lyu , Qing Li , Yuhui Tao , Wei Shao , Qiang Chen , Chengyan Wang , Shuo Wang , Tao Zhou , Yizhe Zhang

Segment Anything Model (SAM), known for its remarkable zero-shot segmentation capabilities, has garnered significant attention in the community. Nevertheless, its performance is challenged when dealing with what we refer to as visually…

Computer Vision and Pattern Recognition · Computer Science 2026-01-05 Guangqian Guo , Pengfei Chen , Yong Guo , Huafeng Chen , Boqiang Zhang , Shan Gao

The Segment Anything Model (SAM) demonstrates impressive zero-shot segmentation ability on natural images but encounters difficulties in medical imaging due to domain shifts, anatomical variability, and its reliance on user-provided…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Yingzhen Hu , Yiheng Zhong , Ruobing Li , Yingxue Su , Jiabao An , Feilong Tang , Jionglong Su , Imran Razzak

Medical image segmentation plays a pivotal role in clinical diagnostics and treatment planning, yet existing models often face challenges in generalization and in handling both 2D and 3D data uniformly. In this paper, we introduce Medical…

Computer Vision and Pattern Recognition · Computer Science 2024-12-06 Jiayuan Zhu , Abdullah Hamdi , Yunli Qi , Yueming Jin , Junde Wu

The Segment Anything Model (SAM) is a deep neural network foundational model designed to perform instance segmentation which has gained significant popularity given its zero-shot segmentation ability. SAM operates by generating masks based…

Computer Vision and Pattern Recognition · Computer Science 2024-04-19 Yona Falinie A. Gaus , Neelanjan Bhowmik , Brian K. S. Isaac-Medina , Toby P. Breckon

While the Segment Anything Model (SAM) has achieved remarkable success in image segmentation, its direct application to medical imaging remains hindered by fundamental challenges, including ambiguous boundaries, insufficient modeling of…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Yu Li , Da Chang , Xi Xiao

Segment Anything Model (SAM) is one of the pioneering prompt-based foundation models for image segmentation and has been rapidly adopted for various medical imaging applications. However, in clinical settings, creating effective prompts is…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Chengyin Li , Prashant Khanduri , Yao Qiang , Rafi Ibn Sultan , Indrin Chetty , Dongxiao Zhu

We present ENSAM (Equivariant, Normalized, Segment Anything Model), a lightweight and promptable model for universal 3D medical image segmentation. ENSAM combines a SegResNet-based encoder with a prompt encoder and mask decoder in a…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Elias Stenhede , Agnar Martin Bjørnstad , Arian Ranjbar

Accurate segmentation of polyps and skin lesions is essential for diagnosing colorectal and skin cancers. While various segmentation methods for polyps and skin lesions using fully supervised deep learning techniques have been developed,…

Computer Vision and Pattern Recognition · Computer Science 2025-04-03 Encheng Su , Hu Cao , Alois Knoll

This study introduces SAMatch, a SAM-guided Match-based framework for semi-supervised medical image segmentation, aimed at improving pseudo label quality in data-scarce scenarios. While Match-based frameworks are effective, they struggle…

Computer Vision and Pattern Recognition · Computer Science 2024-11-27 Guoping Xu , Xiaoxue Qian , Hua Chieh Shao , Jax Luo , Weiguo Lu , You Zhang

The advent of foundation models signals a new era in artificial intelligence. The Segment Anything Model (SAM) is the first foundation model for image segmentation. In this study, we evaluate SAM's ability to segment features from eye…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Virmarie Maquiling , Sean Anthony Byrne , Diederick C. Niehorster , Marcus Nyström , Enkelejda Kasneci

We propose a straightforward yet highly effective few-shot fine-tuning strategy for adapting the Segment Anything (SAM) to anatomical segmentation tasks in medical images. Our novel approach revolves around reformulating the mask decoder…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Weiyi Xie , Nathalie Willems , Shubham Patil , Yang Li , Mayank Kumar

The Segment Anything Model (SAM) is a powerful vision foundation model that is revolutionizing the traditional paradigm of segmentation. Despite this, a reliance on prompting each frame and large computational cost limit its usage in…

Computer Vision and Pattern Recognition · Computer Science 2024-07-03 Zijian Wu , Adam Schmidt , Peter Kazanzides , Septimiu E. Salcudean
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