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While spatial transcriptomics (ST) has advanced our understanding of gene expression in tissue context, its high experimental cost limits its large-scale application. Predicting ST from pathology images is a promising, cost-effective…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Zhiceng Shi , Changmiao Wang , Jun Wan , Wenwen Min

Deep learning-solutions for hand-object 3D pose and shape estimation are now very effective when an annotated dataset is available to train them to handle the scenarios and lighting conditions they will encounter at test time.…

Computer Vision and Pattern Recognition · Computer Science 2020-12-22 Mengshi Qi , Edoardo Remelli , Mathieu Salzmann , Pascal Fua

We present MaskGen, a theoretically grounded and deliberately simple approach for domain generalization in 3D biomedical image segmentation. Modern segmentation models degrade sharply under shifts in modality, disease severity, clinical…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Sebo Diaz , Polina Golland , Elfar Adalsteinsson , Neel Dey

Despite notable advancements, the integration of deep learning (DL) techniques into impactful clinical applications, particularly in the realm of digital histopathology, has been hindered by challenges associated with achieving robust…

Image and Video Processing · Electrical Eng. & Systems 2024-07-04 Sebastian Doerrich , Francesco Di Salvo , Christian Ledig

Unpaired image-to-image translation has emerged as a crucial technique in medical imaging, enabling cross-modality synthesis, domain adaptation, and data augmentation without costly paired datasets. Yet, existing approaches often distort…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Zihao Chen , Yi Zhou , Xudong Jiang , Li Chen , Leopold Schmetterer , Bingyao Tan , Jun Cheng

Single image super-resolution (SISR) is of great importance as a low-level computer vision task. The fast development of Generative Adversarial Network (GAN) based deep learning architectures realises an efficient and effective SISR to…

Image and Video Processing · Electrical Eng. & Systems 2019-01-14 Jin Zhu , Guang Yang , Pietro Lio

Semantic segmentation plays a fundamental role in a broad variety of computer vision applications, providing key information for the global understanding of an image. Yet, the state-of-the-art models rely on large amount of annotated…

Computer Vision and Pattern Recognition · Computer Science 2021-12-07 Gabriela Csurka , Riccardo Volpi , Boris Chidlovskii

Recent studies on unsupervised image-to-image translation have made a remarkable progress by training a pair of generative adversarial networks with a cycle-consistent loss. However, such unsupervised methods may generate inferior results…

Computer Vision and Pattern Recognition · Computer Science 2018-07-31 Minjun Li , Haozhi Huang , Lin Ma , Wei Liu , Tong Zhang , Yu-Gang Jiang

An organ segmentation method that can generalize to unseen contrasts and scanner settings can significantly reduce the need for retraining of deep learning models. Domain Generalization (DG) aims to achieve this goal. However, most DG…

Computer Vision and Pattern Recognition · Computer Science 2022-07-01 Yanwu Xu , Shaoan Xie , Maxwell Reynolds , Matthew Ragoza , Mingming Gong , Kayhan Batmanghelich

Labeling medical images is a major bottleneck in the field of medical imaging, as it requires domain-specific expertise, and it gets further complicated due to variability across different medical centers and different imaging devices. Such…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Sapna Sachan , Rakesh Kumar Sanodiya , Amulya Kumar Mahto

Myocardium segmentation of late gadolinium enhancement (LGE) Cardiac MR images is important for evaluation of infarction regions in clinical practice. The pathological myocardium in LGE images presents distinctive brightness and textures…

Image and Video Processing · Electrical Eng. & Systems 2019-08-15 Xumin Tao , Hongrong Wei , Wufeng Xue , Dong Ni

Deep convolutional neural networks have achieved remarkable progress on a variety of medical image computing tasks. A common problem when applying supervised deep learning methods to medical images is the lack of labeled data, which is very…

Computer Vision and Pattern Recognition · Computer Science 2020-05-12 Xiaomeng Li , Lequan Yu , Hao Chen , Chi-Wing Fu , Lei Xing , Pheng-Ann Heng

Deep learning models in computational pathology often fail to generalize across cohorts and institutions due to domain shift. Existing approaches either fail to leverage unlabeled data from the target domain or rely on image-to-image…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Tengyue Zhang , Ruiwen Ding , Luoting Zhuang , Yuxiao Wu , Erika F. Rodriguez , William Hsu

Medical image segmentation is a crucial task in medical image analysis, but it can be very challenging especially when there are less labeled data but with large unlabeled data. Contrastive learning has proven to be effective for medical…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Shihuan He , Zhihui Lai , Ruxin Wang , Heng Kong

Due to the cross-domain distribution shift aroused from diverse medical imaging systems, many deep learning segmentation methods fail to perform well on unseen data, which limits their real-world applicability. Recent works have shown the…

Computer Vision and Pattern Recognition · Computer Science 2023-03-06 Shangqi Gao , Hangqi Zhou , Yibo Gao , Xiahai Zhuang

Semi-supervised learning (SSL) has made notable advancements in medical image segmentation (MIS), particularly in scenarios with limited labeled data and significantly enhancing data utilization efficiency. Previous methods primarily focus…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 Mengzhu Wang , Jiao Li , Houcheng Su , Nan Yin , Liang Yang , Shen Li

A major challenge in applying deep learning to medical imaging is the paucity of annotated data. This study demonstrates that synthetic colonoscopy images generated by Generative Adversarial Network (GAN) inversion can be used as training…

Image and Video Processing · Electrical Eng. & Systems 2025-07-02 Mayank Golhar , Taylor L. Bobrow , Saowanee Ngamruengphong , Nicholas J. Durr

Training a model to perform a task typically requires a large amount of data from the domains in which the task will be applied. However, it is often the case that data are abundant in some domains but scarce in others. Domain adaptation…

Machine Learning · Computer Science 2019-01-25 Ehsan Hosseini-Asl , Yingbo Zhou , Caiming Xiong , Richard Socher

Unsupervised Domain Adaptation (UDA) is essential for deploying medical segmentation models across diverse clinical environments. Existing methods are fundamentally limited, suffering from semantically unaware feature alignment that results…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Linkuan Zhou , Yinghao Xia , Yufei Shen , Xiangyu Li , Wenjie Du , Cong Cong , Leyi Wei , Ran Su , Qiangguo Jin

Visual Domain Adaptation is a problem of immense importance in computer vision. Previous approaches showcase the inability of even deep neural networks to learn informative representations across domain shift. This problem is more severe…

Computer Vision and Pattern Recognition · Computer Science 2018-04-03 Swami Sankaranarayanan , Yogesh Balaji , Arpit Jain , Ser Nam Lim , Rama Chellappa