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While analysing time-to-event data, it is possible that a certain fraction of subjects will never experience the event of interest and they are said to be cured. When this feature of survival models is taken into account, the models are…

Methodology · Statistics 2020-01-27 Khandoker Akib Mohammad , Yuichi Hirose , Budhi Surya , Yuan Yao

For most if not all cancers, prognosis is of significant importance, and extensive modeling research has been conducted. With the genetic nature of cancer, in the past two decades, multiple types of molecular data (such as gene expressions…

Applications · Statistics 2020-06-09 Sanguo Zhang , Yu Fan , Tingyan Zhong , Shuangge Ma

We propose and study a fully efficient method to estimate associations of an exposure with disease incidence when both, incident cases and prevalent cases, i.e. individuals who were diagnosed with the disease at some prior time point and…

Methodology · Statistics 2018-03-20 Marlena Maziarz , Yukun Liu , Jing Qin , Ruth Pfeiffer

Complex data features, such as unmodelled censored event times and variables with time-dependent effects, are common in cancer recurrence studies and pose challenges for Bayesian survival modelling. Current methodologies for predictive…

Methodology · Statistics 2026-01-12 Saku Suorsa , Aki Vehtari

Semi-parametric survival analysis methods like the Cox Proportional Hazards (CPH) regression (Cox, 1972) are a popular approach for survival analysis. These methods involve fitting of the log-proportional hazard as a function of the…

Machine Learning · Computer Science 2019-05-16 Chirag Nagpal , Rohan Sangave , Amit Chahar , Parth Shah , Artur Dubrawski , Bhiksha Raj

Chronic diseases and cancer account for over 75 percent of healthcare costs in the US. Increased prevention services and improved primary care are thought to decrease costs. Current models for detecting changes in the health of populations…

Populations and Evolution · Quantitative Biology 2013-07-15 Jacob Kuriyan , Nathaniel Cobb

In confirmatory clinical trials, survival outcomes are frequently studied and interim analyses for efficacy and/or futility are often desirable. Methods such as the log rank test and Cox regression model are commonly used to compare…

Methodology · Statistics 2024-03-27 Peter Zhang , Brent Logan , Michael Martens

The spatial scan statistic is widely used to detect disease clusters in epidemiological surveillance. Since the seminal work by~\cite{kulldorff1997}, numerous extensions have emerged, including methods for defining scan regions, detecting…

Methodology · Statistics 2025-02-11 Takayuki Kawashima , Daisuke Yoneoka , Yuta Tanoue , Akifumi Eguchi , Shuhei Nomura

While there are many well-developed data science methods for classification and regression, there are relatively few methods for working with right-censored data. Here, we present "survival stacking": a method for casting survival analysis…

Methodology · Statistics 2021-07-29 Erin Craig , Chenyang Zhong , Robert Tibshirani

Time-to-event data is widespread across the life sciences and engineering, but it is typically encountered together with censoring, which complicates the application of standard machine learning methods. Deep Cox models have emerged as a…

Machine Learning · Statistics 2026-05-19 Anchit Jain , Kevin Zhang , Stephen Bates

Non-terminal events can represent a meaningful change in a patient's life. Thus, better understanding and predicting their occurrence can bring valuable information to individuals. In a context where longitudinal markers could inform these…

Methodology · Statistics 2025-01-16 Juliette Ortholand , Stanley Durrleman , Sophie Tezenas du Montcel

Most epidemic models are spatially aggregate and the index which is most used for planning and policy numbers, the r number, typically refers to a single system of interest. Even if r numbers are calculated for each of adjacent areas,…

Physics and Society · Physics 2020-05-18 Alan Wilson

The characteristics and determinants of health and disease are often organised in space, reflecting our spatially extended nature. Understanding the influence of such factors requires models capable of capturing spatial relations. Though a…

Joint modeling of longitudinal and survival data has become increasingly important in medical research, particularly for understanding disease progression in chronic conditions where both repeated biomarker measurements and time-to-event…

Methodology · Statistics 2025-12-30 Nithisha Suryadevara , Vivek Reddy Srigiri

Survival analysis is a valuable tool for estimating the time until specific events, such as death or cancer recurrence, based on baseline observations. This is particularly useful in healthcare to prognostically predict clinically important…

Machine Learning · Computer Science 2024-01-11 Ahmed H. Shahin , An Zhao , Alexander C. Whitehead , Daniel C. Alexander , Joseph Jacob , David Barber

Deep learning has shown strong performance in geospatial prediction tasks, but the role of geolocation information in improving accuracy and generalizability remains underexamined. Recent work has introduced location encoders that aim to…

Machine Learning · Computer Science 2025-10-28 Morteza Karimzadeh , Zhongying Wang , James L. Crooks

Deep learning survival models often outperform classical methods in time-to-event predictions, particularly in personalized medicine, but their "black box" nature hinders broader adoption. We propose a framework for gradient-based…

Machine Learning · Statistics 2025-02-10 Sophie Hanna Langbein , Niklas Koenen , Marvin N. Wright

Survival prediction for cancer patients is critical for optimal treatment selection and patient management. Current patient survival prediction methods typically extract survival information from patients' clinical record data or biological…

Image and Video Processing · Electrical Eng. & Systems 2024-07-26 Amr Hagag , Ahmed Gomaa , Dominik Kornek , Andreas Maier , Rainer Fietkau , Christoph Bert , Florian Putz , Yixing Huang

Accurate and reliable forecasting of epidemic incidences is critical for public health preparedness, yet it remains a challenging task due to complex nonlinear temporal dependencies and heterogeneous spatial interactions. Often, point…

Machine Learning · Statistics 2026-03-10 Rajdeep Pathak , Tanujit Chakraborty

Principled decision making in emergency response management necessitates the use of statistical models that predict the spatial-temporal likelihood of incident occurrence. These statistical models are then used for proactive stationing…

Machine Learning · Computer Science 2021-06-16 Sayyed Mohsen Vazirizade , Ayan Mukhopadhyay , Geoffrey Pettet , Said El Said , Hiba Baroud , Abhishek Dubey