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Segmenting cells and tracking their motion over time is a common task in biomedical applications. However, predicting accurate instance-wise segmentation and cell motions from microscopy imagery remains a challenging task. Using…

Computer Vision and Pattern Recognition · Computer Science 2024-01-09 Christoph Reich , Tim Prangemeier , Heinz Koeppl

Cell segmentation is a major bottleneck in extracting quantitative single-cell information from microscopy data. The challenge is exasperated in the setting of microstructured environments. While deep learning approaches have proven useful…

Quantitative Methods · Quantitative Biology 2021-01-08 Tim Prangemeier , Christian Wildner , André O. Françani , Christoph Reich , Heinz Koeppl

Cell and nucleus segmentation are fundamental tasks for quantitative bioimage analysis. Despite progress in recent years, biologists and other domain experts still require novel algorithms to handle increasingly large and complex real-world…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Thibaut Goldsborough , Ben Philps , Alan O'Callaghan , Fiona Inglis , Leo Leplat , Andrew Filby , Hakan Bilen , Peter Bankhead

We present a new instance segmentation approach tailored to biological images, where instances may correspond to individual cells, organisms or plant parts. Unlike instance segmentation for user photographs or road scenes, in biological…

Computer Vision and Pattern Recognition · Computer Science 2020-04-24 Victor Kulikov , Victor Lempitsky

In recent years, an enormous amount of fluorescence microscopy images were collected in high-throughput lab settings. Analyzing and extracting relevant information from all images in a short time is almost impossible. Detecting tiny…

Computer Vision and Pattern Recognition · Computer Science 2021-04-08 Asmaa Haja , Lambert R. B. Schomaker

Automatic detection and segmentation of objects in 2D and 3D microscopy data is important for countless biomedical applications. In the natural image domain, spatial embedding-based instance segmentation methods are known to yield…

Image and Video Processing · Electrical Eng. & Systems 2021-04-30 Manan Lalit , Pavel Tomancak , Florian Jug

Automated chromosome instance segmentation from metaphase cell microscopic images is critical for the diagnosis of chromosomal disorders (i.e., karyotype analysis). However, it is still a challenging task due to lacking of densely annotated…

Computer Vision and Pattern Recognition · Computer Science 2023-04-26 Dan You , Pengcheng Xia , Qiuzhu Chen , Minghui Wu , Suncheng Xiang , Jun Wang

Cell instance segmentation is a new and challenging task aiming at joint detection and segmentation of every cell in an image. Recently, many instance segmentation methods have applied in this task. Despite their great success, there still…

Computer Vision and Pattern Recognition · Computer Science 2022-08-18 Menghao Li , Wenquan Feng , Shuchang Lyu , Lijiang Chen , Qi Zhao

In this paper, we propose a new image instance segmentation method that segments individual glands (instances) in colon histology images. This is a task called instance segmentation that has recently become increasingly important. The…

Computer Vision and Pattern Recognition · Computer Science 2016-07-20 Yan Xu , Yang Li , Mingyuan Liu , Yipei Wang , Yubo Fan , Maode Lai , Eric I-Chao Chang

This paper is directed towards the food crystal quality control area for manufacturing, focusing on efficiently predicting food crystal counts and size distributions. Previously, manufacturers used the manual counting method on microscopic…

Computer Vision and Pattern Recognition · Computer Science 2024-09-30 Xiaoyu Ji , Jan P Allebach , Ali Shakouri , Fengqing Zhu

Microscopy data collections are becoming larger and more frequent. Accurate and precise quantitative analysis tools like cell instance segmentation are necessary to benefit from them. This is challenging due to the variability in the data,…

Computer Vision and Pattern Recognition · Computer Science 2024-02-28 Ram J. Zaveri , Voke Brume , Gianfranco Doretto

We present a weakly supervised deep learning method to perform instance segmentation of cells present in microscopy images. Annotation of biomedical images in the lab can be scarce, incomplete, and inaccurate. This is of concern when…

Computer Vision and Pattern Recognition · Computer Science 2019-08-28 Fidel A. Guerrero-Peña , Pedro D. Marrero Fernandez , Tsang Ing Ren , Alexandre Cunha

In laparoscopic and robotic surgery, precise tool instance segmentation is an essential technology for advanced computer-assisted interventions. Although publicly available procedures of routine surgeries exist, they often lack…

Computer Vision and Pattern Recognition · Computer Science 2025-06-05 Oluwatosin Alabi , Ko Ko Zayar Toe , Zijian Zhou , Charlie Budd , Nicholas Raison , Miaojing Shi , Tom Vercauteren

Cell segmentation for multi-modal microscopy images remains a challenge due to the complex textures, patterns, and cell shapes in these images. To tackle the problem, we first develop an automatic cell classification pipeline to label the…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Wei Lou , Xinyi Yu , Chenyu Liu , Xiang Wan , Guanbin Li , Siqi Liu , Haofeng Li

Detecting and segmenting object instances is a common task in biomedical applications. Examples range from detecting lesions on functional magnetic resonance images, to the detection of tumours in histopathological images and extracting…

Computer Vision and Pattern Recognition · Computer Science 2021-04-12 Tim Prangemeier , Christoph Reich , Heinz Koeppl

Instance segmentation of biological images is essential for studying object behaviors and properties. The challenges, such as clustering, occlusion, and adhesion problems of the objects, make instance segmentation a non-trivial task.…

Computer Vision and Pattern Recognition · Computer Science 2019-11-22 Jingru Yi , Hui Tang , Pengxiang Wu , Bo Liu , Daniel J. Hoeppner , Dimitris N. Metaxas , Lianyi Han , Wei Fan

Semantic segmentation and object detection research have recently achieved rapid progress. However, the former task has no notion of different instances of the same object, and the latter operates at a coarse, bounding-box level. We propose…

Computer Vision and Pattern Recognition · Computer Science 2017-04-11 Anurag Arnab , Philip H. S Torr

Cell segmentation is a critical step for quantitative single-cell analysis in microscopy images. Existing cell segmentation methods are often tailored to specific modalities or require manual interventions to specify hyper-parameters in…

Virtually all aspects of modern life depend on space technology. Thanks to the great advancement of computer vision in general and deep learning-based techniques in particular, over the decades, the world witnessed the growing use of deep…

Computer Vision and Pattern Recognition · Computer Science 2021-06-16 Dung Anh Hoang , Bo Chen , Tat-Jun Chin

Recent trends in cell segmentation have shifted towards universal models to handle diverse cell morphologies and imaging modalities. However, for continuously emerging cell types and imaging techniques, these models still require hundreds…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Peilin Zhou , Bo Du , Yongchao Xu
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