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We studied how the inhomogeneity of a sequence affects the phase transition that takes place at DNA melting. Unlike previous works, which considered thermodynamic quantities averaged over many different inhomogeneous sequences, we focused…

Biological Physics · Physics 2008-03-07 Sahin Buyukdagli , Marc Joyeux

The importance of torsion vibration in the transmission of life information is indicated. The localization of quantum torsion state is proved. Following these analyses a formalism on the quantum theory of conformation-electron system is…

Biomolecules · Quantitative Biology 2009-06-16 Liaofu Luo

We study experimentally the thermal fluctuations of energy input and dissipation in a harmonic oscillator driven out of equilibrium, and search for Fluctuation Relations. We study transient evolution from the equilibrium state, together…

Statistical Mechanics · Physics 2007-11-28 Sylvain Joubaud , Nicolas Garnier , Sergio Ciliberto

We study the noise characteristics of stochastic oscillations in protein number dynamics of simple genetic oscillatory systems. Using the three-component negative feedback transcription regulatory system called the repressilator as a…

Molecular Networks · Quantitative Biology 2015-03-13 Byungjoon Min , K. -I. Goh , I. -M. Kim

The time-periodic modulation of a temperature gradient can alter the heat transport properties of a physical system. Oscillating thermal gradients give rise to behaviors such as modified thermal conductivity and controllable time-delayed…

Mesoscale and Nanoscale Physics · Physics 2024-04-22 Renai Chen , Tammie Gibson , Galen T. Craven

When a chemical reaction is driven by an external field, the transition state that the system must pass through as it changes from reactant to product -for example, an energy barrier- becomes time-dependent. We show that for periodic…

Chemical Physics · Physics 2015-05-01 Galen T. Craven , Thomas Bartsch , Rigoberto Hernandez

The fidelity of operations on a solid-state quantum processor is fundamentally bounded by environmental decoherence. Characterizing environmental fluctuations is challenging because the acquisition time of nonadaptive experimental protocols…

The time-dependent optical properties of molecular systems are investigated by step-scan Fourier-transform spectroscopy in order to explore the dynamics at phase transitions and molecular orientation in the milli- and microsecond range. The…

Materials Science · Physics 2016-07-20 Tobias Peterseim , Martin Dressel

How does soil pollution affect a plant's circadian clock? Are there any differences between how the clock reacts when exposed to different concentrations of elements of the periodic table? If so, can we characterise these differences? We…

Applications · Statistics 2016-08-01 Jessica K. Hargreaves , Marina I. Knight , Jon W. Pitchford , Seth J. Davis

Cells generally convert nutrient resources to useful products via energy transduction. Accordingly, the thermodynamic efficiency of this conversion process is one of the most essential characteristics of living organisms. However, although…

Biological Physics · Physics 2016-05-04 Yusuke Himeoka , Kunihiko Kaneko

Biological systems process information under noisy environment. Sensory adaptation model of E. coli is suitable for investigation because of its simplicity. To understand the adaptation processing quantitatively, stochastic thermodynamic…

Molecular Networks · Quantitative Biology 2019-07-16 Keita Ashida , Kotaro Oka

By means of Metropolis Monte Carlo simulations of a coarse-grained model for flexible polymers, we investigate how the integrated autocorrelation times of different energetic and structural quantities depend on the temperature. We show…

Computational Physics · Physics 2014-08-19 Kai Qi , Michael Bachmann

The earliest molecular dynamics simulations relied on solving the Newtonian or equivalently the Hamiltonian equations of motion for a system. While pedagogically very important as the total energy is preserved in these simulations, they…

Computational Physics · Physics 2020-06-04 M Sri Harish , Puneet Kumar Patra

We present a rigorous and efficient approach to the calculation of classical lattice-dynamical quantities from simulations that do not require an explicit solution of the time evolution. We focus on the temperature-dependent vibrational…

Materials Science · Physics 2013-03-14 Mathias P. Ljungberg , Jorge Íñiguez

RNA thermometers are mRNA strands with a temperature dependent secondary structure: depending on the spatial conformation, the mRNA strand can get translated (on-state) or can be inaccessible for ribosomes binding (off-state). These have…

In this theoretical study, we focus on the high-frequency response of the electrothermal NbO2-Mott threshold switch, a real-world electronic device, which has been proved to be relevant in several applications and is classified as a…

Mesoscale and Nanoscale Physics · Physics 2024-04-18 Ioannis Messaris , Alon Ascoli , Ahmet S. Demirkol , Vasileios Ntinas , Dimitrios Prousalis , Ronald Tetzlaff

Eukaryotic gene regulation is based on stochastic yet controlled promoter switching, during which genes transition between transcriptionally active and inactive states. Despite the molecular complexity of this process, recent studies reveal…

Molecular Networks · Quantitative Biology 2025-07-17 Benjamin Zoller , Alexis Bénichou , Thomas Gregor , Gašper Tkačik

How can a microorganism adapt to a variety of environmental conditions despite there exists a limited number of signal transduction machineries? We show that for any growing cells whose gene expression is under stochastic fluctuations,…

Molecular Networks · Quantitative Biology 2015-05-13 Chikara Furusawa , Kunihiko Kaneko

Organisms are equipped with regulatory systems that display a variety of dynamical behaviours ranging from simple stable steady states, to switching and multistability, to oscillations. Earlier work has shown that oscillations in protein…

Molecular Networks · Quantitative Biology 2009-11-13 Simone Pigolotti , Sandeep Krishna , Mogens H. Jensen

During development, morphogen gradients precisely determine the position of gene expression boundaries despite the inevitable presence of fluctuations. Recent experiments suggest that some morphogen gradients may be interpreted prior to…

Molecular Networks · Quantitative Biology 2009-11-30 Timothy E Saunders , Martin Howard