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Background: The study of genome-scale metabolic models and their underlying networks is one of the most important fields in systems biology. The complexity of these models and their description makes the use of computational tools an…

Molecular Networks · Quantitative Biology 2012-12-03 D. Gamermann , A. Montagud , R. A. Jaime Infante , J. Triana , P. F. de Córdoba , J. F. Urchueguía

We describe a system for visualization and editing of data in a computational chemistry environment. The system is a collaborative tool allowing researchers using virtual reality and/or desktop computer displays to work together on results…

Graphics · Computer Science 2023-10-04 Dave Pape , Amin Ghadersohi , Josephine Anstey , Amit Makwana

Data visualizations summarize high-dimensional distributions in two or three dimensions. Dimensionality reduction entails a loss of information, and what is preserved differs between methods. Existing methods preserve the local or the…

Computation · Statistics 2021-07-05 Andrew D Zaharia , Anish S Potnis , Alexander Walther , Nikolaus Kriegeskorte

Open material databases storing hundreds of thousands of material structures and their corresponding properties have become the cornerstone of modern computational materials science. Yet, the raw outputs of the simulations, such as the…

Application of machine learning techniques enables segmentation of functional tissue units in histology whole-slide images (WSIs). We built a pipeline to apply previously validated segmentation models of kidney structures and extract…

With the rapid adoption of machine learning techniques for large-scale applications in science and engineering comes the convergence of two grand challenges in visualization. First, the utilization of black box models (e.g., deep neural…

Quantitative analysis of multidimensional biological images is useful for understanding complex cellular phenotypes and accelerating advances in biomedical research. As modern microscopy generates ever-larger 2D and 3D datasets, existing…

Computer Vision and Pattern Recognition · Computer Science 2025-10-17 Alexandr A. Kalinin , Anne E. Carpenter , Shantanu Singh , Matthew J. O'Meara

Multilayer networks are widely used across biology to represent systems in which complex networks vary across space, time, or interaction types. However, interactive visualization tools remain limited. We present MiRA (Multilayer…

Social and Information Networks · Computer Science 2026-05-14 Shir Miryam Nehoray , Yuval Bloch , Shai Pilosof

This paper introduces a novel software visualisation and animation method, manifested in a prototype software tool - AnimArch. The introduced method is based on model fusion of static and dynamic models. The static model is represented by…

Software Engineering · Computer Science 2025-01-15 Lukas Radosky , Ivan Polasek

Image- and data-parallel rendering across multiple nodes on high-performance computing systems is widely used in visualization to provide higher frame rates, support large data sets, and render data in situ. Specifically for in situ…

Graphics · Computer Science 2023-05-15 Will Usher , Ingo Wald , Jefferson Amstutz , Johannes Günther , Carson Brownlee , Valerio Pascucci

pyssam is a Python library for creating statistical shape and appearance models (SSAMs) for biological (and other) shapes such as bones, lungs or other organs. A point cloud best describing the anatomical 'landmarks' of the organ are…

Quantitative Methods · Quantitative Biology 2023-01-12 Josh Williams , Ali Ozel , Uwe Wolfram

Anthropogenic pollution of hydrological systems affects diverse communities and ecosystems around the world. Data analytics and modeling tools play a key role in fighting this challenge, as they can help identify key sources as well as…

Machine Learning · Computer Science 2023-09-26 David L. Cole , Gerardo J. Ruiz-Mercado , Victor M. Zavala

Given a large social or computer network, how can we visualize it, find patterns, outliers, communities? Although several graph visualization tools exist, they cannot handle large graphs with hundred thousand nodes and possibly million…

Social and Information Networks · Computer Science 2015-07-07 Jose Rodrigues , Agma Traina , Christos Faloutsos , Caetano Traina

Analysis of genomics data is central to nearly all areas of modern biology. Despite significant progress in artificial intelligence (AI) and computational methods, these technologies require significant human oversight to generate novel and…

Drug discovery aims at designing novel molecules with specific desired properties for clinical trials. Over past decades, drug discovery and development have been a costly and time consuming process. Driven by big chemical data and AI, deep…

Machine Learning · Computer Science 2020-07-22 Karan Yang , Chengxi Zang , Fei Wang

This paper introduces SynthDoc, a novel synthetic document generation pipeline designed to enhance Visual Document Understanding (VDU) by generating high-quality, diverse datasets that include text, images, tables, and charts. Addressing…

Computer Vision and Pattern Recognition · Computer Science 2024-08-28 Chuanghao Ding , Xuejing Liu , Wei Tang , Juan Li , Xiaoliang Wang , Rui Zhao , Cam-Tu Nguyen , Fei Tan

Effective data visualization is a key part of the discovery process in the era of big data. It is the bridge between the quantitative content of the data and human intuition, and thus an essential component of the scientific path from data…

In this paper, we present BIMS (Biomedical Information Management System). BIMS is a software architecture designed to provide a flexible computational framework to manage the information needs of a wide range of biomedical research…

Software Engineering · Computer Science 2013-03-26 Oscar Mora , Jesús Bisbal

Advances in entity-graph based analysis of histopathology images have brought in a new paradigm to describe tissue composition, and learn the tissue structure-to-function relationship. Entity-graphs offer flexible and scalable…

Image and Video Processing · Electrical Eng. & Systems 2021-07-22 Guillaume Jaume , Pushpak Pati , Valentin Anklin , Antonio Foncubierta , Maria Gabrani

One approach to studying the system-wide organization of biochemistry is to use statistical graph theory. Even in such a heavily simplified method, which disregards most of the dynamic aspects of biochemistry, one is faced with fundamental…

Molecular Networks · Quantitative Biology 2010-08-17 Petter Holme , Mikael Huss