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The hypothalamus is a small structure located in the center of the brain and is involved in significant functions such as sleeping, temperature, and appetite control. Various neurological disorders are also associated with hypothalamic…

Background: The hippocampus plays a crucial role in memory and cognition. Because of the associated toxicity from whole brain radiotherapy, more advanced treatment planning techniques prioritize hippocampal avoidance, which depends on an…

Medical Physics · Physics 2023-06-16 Yang Lei , Yifu Ding , Richard L. J. Qiu , Tonghe Wang , Justin Roper , Yabo Fu , Hui-Kuo Shu , Hui Mao , Xiaofeng Yang

Brain tissue segmentation has demonstrated great utility in quantifying MRI data through Voxel-Based Morphometry and highlighting subtle structural changes associated with various conditions within the brain. However, manual segmentation is…

Image and Video Processing · Electrical Eng. & Systems 2023-02-02 Vishwanatha M. Rao , Zihan Wan , Soroush Arabshahi , David J. Ma , Pin-Yu Lee , Ye Tian , Xuzhe Zhang , Andrew F. Laine , Jia Guo

Segmentation of structural and diffusion MRI (sMRI/dMRI) is usually performed independently in neuroimaging pipelines. However, some brain structures (e.g., globus pallidus, thalamus and its nuclei) can be extracted more accurately by…

Computer Vision and Pattern Recognition · Computer Science 2019-03-12 Juan Eugenio Iglesias , Koen Van Leemput , Polina Golland , Anastasia Yendiki

Segmenting vascular pathologies such as white matter lesions in Brain magnetic resonance images (MRIs) require acquisition of multiple sequences such as T1-weighted (T1-w) --on which lesions appear hypointense-- and fluid attenuated…

Computer Vision and Pattern Recognition · Computer Science 2018-08-21 Mauricio Orbes-Arteaga , M. Jorge Cardoso , Lauge Sørensen , Marc Modat , Sébastien Ourselin , Mads Nielsen , Akshay Pai

Neuroanatomical segmentation in magnetic resonance imaging (MRI) of the brain is a prerequisite for volume, thickness and shape measurements. This work introduces a new highly accurate and versatile method based on 3D convolutional neural…

Quantitative Methods · Quantitative Biology 2019-02-07 Philip Novosad , Vladimir Fonov , D. Louis Collins

Digital pathology, augmented by artificial intelligence (AI), holds significant promise for improving the workflow of pathologists. However, challenges such as the labor-intensive annotation of whole slide images (WSIs), high computational…

Image and Video Processing · Electrical Eng. & Systems 2025-04-18 Walid Rehamnia , Alexandra Getmanskaya , Evgeniy Vasilyev , Vadim Turlapov

Segmenting the boundary between tumor and healthy tissue during surgical cancer resection poses a significant challenge. In recent years, Hyperspectral Imaging (HSI) combined with Machine Learning (ML) has emerged as a promising solution.…

Multi-modal magnetic resonance imaging (MRI) plays a crucial role in comprehensive disease diagnosis in clinical medicine. However, acquiring certain modalities, such as T2-weighted images (T2WIs), is time-consuming and prone to be with…

Image and Video Processing · Electrical Eng. & Systems 2024-05-22 Qi Wang , Zhijie Wen , Jun Shi , Qian Wang , Dinggang Shen , Shihui Ying

Complete and high-quality multi-modal Magnetic Resonance Imaging (MRI) is essential for accurate neuro-oncological assessment, as each contrast provides complementary anatomical and pathological information. However, acquiring all…

Image and Video Processing · Electrical Eng. & Systems 2026-05-04 Zaid A. Abod , Furqan Aziz

The thrombotic microangiopathies (TMAs) manifest in renal biopsy histology with a broad spectrum of acute and chronic findings. Precise diagnostic criteria for a renal biopsy diagnosis of TMA are missing. As a first step towards a machine…

Tumor segmentation in whole-slide images of histology slides is an important step towards computer-assisted diagnosis. In this work, we propose a tumor segmentation framework based on the novel concept of persistent homology profiles…

Computer Vision and Pattern Recognition · Computer Science 2018-05-11 Talha Qaiser , Yee-Wah Tsang , Daiki Taniyama , Naoya Sakamoto , Kazuaki Nakane , David Epstein , Nasir Rajpoot

This paper proposes an advanced method for contrast enhancement of capsule endoscopic images, with the main objective to obtain sufficient information about the vessels and structures in more distant (or darker) parts of capsule endoscopic…

Image and Video Processing · Electrical Eng. & Systems 2021-04-09 Olivier Rukundo , Marius Pedersen , Øistein Hovde

The human thalamus is a brain structure that comprises numerous, highly specific nuclei. Since these nuclei are known to have different functions and to be connected to different areas of the cerebral cortex, it is of great interest for the…

Recent studies on T1-assisted MRI reconstruction for under-sampled images of other modalities have demonstrated the potential of further accelerating MRI acquisition of other modalities. Most of the state-of-the-art approaches have achieved…

Image and Video Processing · Electrical Eng. & Systems 2021-11-15 Junwei Yang , Xiao-Xin Li , Feihong Liu , Dong Nie , Pietro Lio , Haikun Qi , Dinggang Shen

Single-image HDR reconstruction or inverse tone mapping (iTM) is a challenging task. In particular, recovering information in over-exposed regions is extremely difficult because details in such regions are almost completely lost. In this…

Image and Video Processing · Electrical Eng. & Systems 2021-07-19 Kanglin Liu , Gaofeng Cao , Jiang Duan , Guoping Qiu

Limited amount of labelled training data are a common problem in medical imaging. This makes it difficult to train a well-generalised model and therefore often leads to failure in unknown domains. Hippocampus segmentation from magnetic…

Image and Video Processing · Electrical Eng. & Systems 2022-01-19 John Kalkhof , Camila González , Anirban Mukhopadhyay

Accurate segmentation and classification of nuclei in histology images is critical but challenging due to nuclei heterogeneity, staining variations, and tissue complexity. Existing methods often struggle with limited dataset variability,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Wenhua Zhang , Sen Yang , Meiwei Luo , Chuan He , Yuchen Li , Jun Zhang , Xiyue Wang , Fang Wang

Deep Brain Stimulation (DBS) is one of the most successful methods to diminish late-stage Parkinson's Disease (PD) symptoms. It is a delicate surgical procedure which requires detailed pre-surgical patient's study. High-field Magnetic…

Image and Video Processing · Electrical Eng. & Systems 2024-07-23 Tomás Lima , Igor Varga , Eduard Bakštein , Daniel Novák , Victor Alves