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Heterogeneity is a fundamental characteristic of cancer. To accommodate heterogeneity, subgroup identification has been extensively studied and broadly categorized into unsupervised and supervised analysis. Compared to unsupervised…
Anomaly detection in X-ray images has been an active and lasting research area in the last decades, especially in the domain of medical X-ray images. For this work, we created a real-world labeled anomaly dataset, consisting of 16-bit X-ray…
Pathological brain lesions exhibit diverse appearance in brain images, in terms of intensity, texture, shape, size, and location. Comprehensive sets of data and annotations are difficult to acquire. Therefore, unsupervised anomaly detection…
Molecular data from tumor profiles is high dimensional. Tumor profiles can be characterized by tens of thousands of gene expression features. Due to the size of the gene expression feature set machine learning methods are exposed to noisy…
Breast cancer is a heterogeneous disease with different molecular subtypes, clinical behavior, treatment responses as well as survival outcomes. The development of a reliable, accurate, available and inexpensive method to predict the…
Congenital malformations of the brain are among the most common fetal abnormalities that impact fetal development. Previous anomaly detection methods on ultrasound images are based on supervised learning, rely on manual annotations, and…
Accurate quantification in positron emission tomography (PET) is essential for accurate diagnostic results and effective treatment tracking. A major issue encountered in PET imaging is attenuation. Attenuation refers to the diminution of…
The time-consuming task of manual segmentation challenges routine systematic quantification of disease burden. Convolutional neural networks (CNNs) hold significant promise to reliably identify locations and boundaries of tumors from PET…
Graph anomaly detection on attributed networks has become a prevalent research topic due to its broad applications in many influential domains. In real-world scenarios, nodes and edges in attributed networks usually display distinct…
Multivariate time series (MTS) anomaly detection identifies abnormal patterns where each timestamp contains multiple variables. Existing MTS anomaly detection methods fall into three categories: reconstruction-based, prediction-based, and…
Unsupervised anomaly detection (UAD) aims to find anomalous images by optimising a detector using a training set that contains only normal images. UAD approaches can be based on reconstruction methods, self-supervised approaches, and…
Lack of large expert annotated MR datasets makes training deep learning models difficult. Therefore, a cross-modality (MR-CT) deep learning segmentation approach that augments training data using pseudo MR images produced by transforming…
Unsupervised graph-level anomaly detection (UGAD) has received remarkable performance in various critical disciplines, such as chemistry analysis and bioinformatics. Existing UGAD paradigms often adopt data augmentation techniques to…
Medical image segmentation plays an important role in computer-aided diagnosis. Existing methods mainly utilize spatial attention to highlight the region of interest. However, due to limitations of medical imaging devices, medical images…
Breast cancer, the second leading cause of cancer-related deaths globally, accounts for a quarter of all cancer cases [1]. To lower this death rate, it is crucial to detect tumors early, as early-stage detection significantly improves…
This work tackles the unsupervised cross-domain object detection problem which aims to generalize a pre-trained object detector to a new target domain without labels. We propose an uncertainty-aware model adaptation method, which is based…
Early detection of lung nodules with computed tomography (CT) is critical for the longer survival of lung cancer patients and better quality of life. Computer-aided detection/diagnosis (CAD) is proven valuable as a second or concurrent…
Computer aided pathological analysis has been the gold standard for tumor diagnosis, however domain shift is a significant problem in histopathology. It may be caused by variability in anatomical structures, tissue preparation, and imaging…
Anomaly detection has many applications ranging from bank-fraud detection and cyber-threat detection to equipment maintenance and health monitoring. However, choosing a suitable algorithm for a given application remains a challenging design…
Cardiac amyloidosis (CA) is a rare cardiomyopathy, with typical abnormalities in clinical measurements from echocardiograms such as reduced global longitudinal strain of the myocardium. An alternative approach for detecting CA is via neural…