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There is intense interest in applying machine learning to problems of causal inference in fields such as healthcare, economics and education. In particular, individual-level causal inference has important applications such as precision…

Machine Learning · Statistics 2017-05-17 Uri Shalit , Fredrik D. Johansson , David Sontag

Across research disciplines, cluster randomized trials (CRTs) are commonly implemented to evaluate interventions delivered to groups of participants, such as communities and clinics. Despite advances in the design and analysis of CRTs,…

Confidence estimation infers a probability for whether each model output is correct or not. While predicting such binary correctness is sensible for tasks with exact answers, free-form generation tasks are often more nuanced, with output…

Computation and Language · Computer Science 2026-01-14 Chi-Yang Hsu , Alexander Braylan , Yiheng Su , Matthew Lease , Omar Alonso

Augmenting randomized controlled trials (RCTs) with external real-world data (RWD) has the potential to improve the finite sample efficiency of treatment effect estimators. We describe using adaptive targeted maximum likelihood estimation…

Methodology · Statistics 2025-01-30 Sky Qiu , Jens Tarp , Andrew Mertens , Mark van der Laan

Real-Time Bidding (RTB) is revolutionising display advertising by facilitating per-impression auctions to buy ad impressions as they are being generated. Being able to use impression-level data, such as user cookies, encourages user…

Computer Science and Game Theory · Computer Science 2016-03-04 Weinan Zhang , Yifei Rong , Jun Wang , Tianchi Zhu , Xiaofan Wang

In computational advertising, a challenging problem is how to recommend the bid for advertisers to achieve the best return on investment (ROI) given budget constraint. This paper presents a bid recommendation scenario that discovers the…

Information Retrieval · Computer Science 2022-12-29 Deguang Kong , Konstantin Shmakov , Jian Yang

There is a growing literature on design-based methods to estimate average treatment effects for randomized controlled trials (RCTs) using the underpinnings of experiments. In this article, we build on these methods to consider design-based…

Methodology · Statistics 2024-01-17 Peter Z Schochet

Disease progression simulation is a crucial area of research that has significant implications for clinical diagnosis, prognosis, and treatment. One major challenge in this field is the lack of continuous medical imaging monitoring of…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Kaizhao Liang , Xu Cao , Kuei-Da Liao , Tianren Gao , Wenqian Ye , Zhengyu Chen , Jianguo Cao , Tejas Nama , Jimeng Sun

Randomized controlled trials generate experimental variation that can credibly identify causal effects, but often suffer from limited scale, while observational datasets are large, but often violate desired identification assumptions. To…

Econometrics · Economics 2023-12-27 George Z. Gui

Unmeasured confounding, unethical exposure, and ill-defined interventions pose significant challenges to evaluating policy-relevant mediation estimands in medicine and public health. In observational studies involving harmful exposures, the…

Methodology · Statistics 2026-05-12 Yang Bai , Yifan Cui , Baoluo Sun

Reranking improves recommendation quality by modeling item interactions. However, existing methods often decouple ranking and reranking, leading to weak listwise evaluation models that suffer from combinatorial sparsity and limited…

Information Retrieval · Computer Science 2025-11-27 Guoxiao Zhang , Tan Qu , Ao Li , DongLin Ni , Qianlong Xie , Xingxing Wang

Recommender systems are central to digital platforms, yet they face a fundamental trade-off between accuracy and explainability. Black-box models achieve strong performance but lack interpretability needed for trust and adoption. Existing…

Information Retrieval · Computer Science 2026-05-05 Yuyan Wang , Pan Li , Minmin Chen

Estimating causal effects from observational data is inherently challenging due to the lack of observable counterfactual outcomes and even the presence of unmeasured confounding. Traditional methods often rely on restrictive, untestable…

Methodology · Statistics 2025-04-07 Li Chen , Xiaotong Shen , Wei Pan

In causal inference, encouragement designs (EDs) are widely used to analyze causal effects, when randomized controlled trials (RCTs) are impractical or compliance to treatment cannot be perfectly enforced. Unlike RCTs, which directly…

Machine Learning · Computer Science 2024-12-20 Anpeng Wu , Kun Kuang , Ruoxuan Xiong , Xiangwei Chen , Zexu Sun , Fei Wu , Kun Zhang

Randomized Controlled Trials (RCT) are the current gold standards to empirically measure the effect of a new drug. However, they may be of limited size and resorting to complementary non-randomized data, referred to as observational, is…

Methodology · Statistics 2025-06-11 Ahmed Boughdiri , Julie Josse , Erwan Scornet

Accurately quantifying uncertainty of individual treatment effects (ITEs) across multiple decision points is crucial for personalized decision-making in fields such as healthcare, finance, education, and online marketplaces. Previous work…

Methodology · Statistics 2025-12-10 Swaraj Bose , Walter Dempsey

The ranking of experiments by expected information gain (EIG) in Bayesian experimental design is sensitive to changes in the model's prior distribution, and the approximation of EIG yielded by sampling will have errors similar to the use of…

Machine Learning · Statistics 2022-05-23 Jinwoo Go , Tobin Isaac

In randomized experiments, regression adjustment can improve the precision of average treatment effect (ATE) estimation using covariates without requiring a correctly specified outcome model. Although well studied in low-dimensional…

Statistics Theory · Mathematics 2026-04-28 Dogyoon Song

Influence maximization is the problem of selecting top $k$ seed nodes in a social network to maximize their influence coverage under certain influence diffusion models. In this paper, we propose a novel algorithm IRIE that integrates a new…

Social and Information Networks · Computer Science 2012-03-20 Kyomin Jung , Wooram Heo , Wei Chen

Objective: Randomised controlled trials (RCTs) are widely considered as gold standard for assessing the effectiveness of new health interventions. When treatment non-compliance is present in RCTs, the treatment effect in the subgroup of…

Applications · Statistics 2025-03-25 Theodosios Papazoglou , Ed Waddingham , Alastair Young