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Growing experimental evidence indicates that topological defects could serve as organizing centers in the morphogenesis of tissues. Here, we provide a quantitative explanation for this phenomenon, rooted in the buckling theory of deformable…

Soft Condensed Matter · Physics 2022-04-21 Ludwig A. Hoffmann , Livio Nicola Carenza , Julia Eckert , Luca Giomi

Cultured stem cells have become a standard platform not only for regenerative medicine and developmental biology but also for biophysical studies. Yet, the characterization of cultured stem cells at the level of morphology and macroscopic…

Soft Condensed Matter · Physics 2022-06-23 Kyogo Kawaguchi , Ryoichiro Kageyama , Masaki Sano

We have studied the collective motion of polar active particles confined to ellipsoidal surfaces. The geometric constraints lead to the formation of vortices that encircle surface points of constant curvature (umbilics). We have found that…

Soft Condensed Matter · Physics 2017-07-04 Sebastian Ehrig , Jonathan Ferracci , Richard Weinkamer , John W. C. Dunlop

Heteroepitaxial structures based on Bi$_{2}$Te$_{3}$-type topological insulators (TIs) exhibit exotic quantum phenomena. For optimal characterization of these phenomena, it is desirable to control the interface structure during film growth…

We establish how active stress globally affects the morphology of disclination lines of a three dimensional active nematic liquid crystal under chaotic flow. Thanks to a defect detection algorithm based on the local nematic orientation, we…

Soft Condensed Matter · Physics 2025-06-30 Pasquale Digregorio , Cecilia Rorai , Ignacio Pagonabarraga , Federico Toschi

In confluent cell monolayers, patterns of cell forces and motion are systematically altered near topological defects in cell shape. In turn, defects have been proposed to alter cell density, extrusion, and invasion, but it remains unclear…

Biological Physics · Physics 2025-08-11 Pradip K. Bera , Molly McCord , Jun Zhang , Jacob Notbohm

Nontrivial properties of electronic states in topological insulators are inherent not only to the surface and boundary states, but to bound states localized at structure defects as well. We clarify how the unusual properties of the…

Mesoscale and Nanoscale Physics · Physics 2016-09-19 Vladimir A. Sablikov , Aleksei A. Sukhanov

Active matter refers to a broad class of non-equilibrium systems where energy is continuously injected at the level of individual ``particles". These systems exhibit emergent collective behaviors that have no direct thermal-equilibrium…

Soft Condensed Matter · Physics 2026-02-10 Zihan Zheng , Cunyuan Jiang , Yangrui Chen , Matteo Baggioli , Jie Zhang

Topological defects, which are singular points in a director field, play a major role in shaping active systems. Here, we experimentally study topological defects and the flow patterns around them, that are formed during the highly rapid…

Soft Condensed Matter · Physics 2024-03-20 Victor Yashunsky , Daniel J. G. Pearce , Gil Ariel , Avraham Be'er

We investigate the dynamics of elastic capsules suspended in two-dimensional active nematic fluids using lattice Boltzmann simulations. The capsules, modeled as flexible membranes enclosing active internal regions, exhibit a rich variety of…

Soft Condensed Matter · Physics 2026-04-13 Júlio P. A. Santos , Margarida M. Telo da Gama , Rodrigo C. V. Coelho

We explore the pressure of active particles on curved surfaces and its relation to other interfacial properties. We use both direct simulations of the active systems as well as simulations of an equilibrium system with effective (pair)…

Soft Condensed Matter · Physics 2019-05-14 René Wittmann , Frank Smallenburg , Joseph M. Brader

Hypothesis Understanding wetting behavior is of great importance for natural systems and technological applications. The traditional concept of contact angle, a purely geometrical measure related to curvature, is often used for…

The presence and significance of active topological defects is increasingly realised in diverse biological and biomimetic systems. We introduce a continuum model of polar active matter, based on conservation laws and symmetry arguments,…

Soft Condensed Matter · Physics 2021-06-08 Aboutaleb Amiri , Romain Mueller , Amin Doostmohammadi

Morphological trends in growing colonies of living cells are at the core of physiological and evolutionary processes. Using active gel equations, which include cell division, we show that shape changes during the growth can be regulated by…

Soft Condensed Matter · Physics 2016-07-27 Amin Doostmohammadi , Sumesh P. Thampi , Julia M. Yeomans

In the last years self-motile droplets attracted the attention of scientists from different fields ranging from applied biology to theoretical physics, because of their promising technological applications and important biological…

Soft Condensed Matter · Physics 2023-03-31 L. N. Carenza , G. Gonnella , G. Negro

Locomotion of bacteria by actin polymerization, and in vitro motion of spherical beads coated with a protein catalyzing polymerization, are examples of active motility. Starting from a simple model of forces locally normal to the surface of…

Statistical Mechanics · Physics 2009-11-10 Allen Lee , Ha Youn Lee , Mehran Kardar

Topological defects in nematically aligned cell populations play a critical role in modulating collective motion, from microbial colonies to epithelial tissues. Despite the potential of manipulating such topological defects to control…

Soft Condensed Matter · Physics 2023-07-25 Ryo Ienaga , Kazusa Beppu , Yusuke T. Maeda

Topological defects are crucial to the thermodynamics and structure of condensed matter systems. For instance, when incorporated into crystalline membranes like graphene, disclinations with positive and negative topological charge…

Soft Condensed Matter · Physics 2018-08-29 Isaac R. Bruss , Gregory M. Grason

The morphology of a mixture made of a polar active gel immersed in an isotropic passive fluid is studied numerically. Lattice Boltzmann method is adopted to solve the Navier-Stokes equation and coupled to a finite-difference scheme used to…

Soft Condensed Matter · Physics 2019-11-22 Livio Nicola Carenza , Giuseppe Gonnella , Antonio Lamura , Giuseppe Negro

Bumps are omnipresent from human skin to the geological structures on planets, which offer distinct advantages in numerous phenomena including structural color, drag reduction, and extreme wettability. Although the topographical parameters…

Fluid Dynamics · Physics 2016-03-23 Kyoo-Chul Park , Philseok Kim , Neil He , Joanna Aizenberg
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