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Explainable AI (XAI) techniques are necessary to help clinicians make sense of AI predictions and integrate predictions into their decision-making workflow. In this work, we conduct a survey study to understand clinician preference among…

Computation and Language · Computer Science 2025-08-28 Jun Hou , Lucy Lu Wang

As medical LLMs transition to clinical deployment, assessing their ethical reasoning capability becomes critical. While achieving high accuracy on knowledge benchmarks, LLMs lack validated assessment for navigating ethical trade-offs in…

Computation and Language · Computer Science 2026-04-21 Chang Hong , Minghao Wu , Qingying Xiao , Yuchi Wang , Xiang Wan , Guangjun Yu , Benyou Wang , Yan Hu

Artificial intelligence (AI) systems, particularly those based on deep learning models, have increasingly achieved expert-level performance in medical applications. However, there is growing concern that such AI systems may reflect and…

Computation and Language · Computer Science 2025-04-25 Xiuying Chen , Tairan Wang , Juexiao Zhou , Zirui Song , Xin Gao , Xiangliang Zhang

Developing AI models that are useful in clinical practice, requires efficient collaboration between clinicians and AI developers. This poses a practical challenge: clinicians must repeatedly communicate and refine their requirements with AI…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Zihao Zhao , Frederik Hauke , Juliana De Castilhos , Mathis Bode , Jakob Nikolas Kather , Sven Nebelung , Daniel Truhn

We present SQuAI (https://squai.scads.ai/), a scalable and trustworthy multi-agent retrieval-augmented generation (RAG) framework for scientific question answering (QA) with large language models (LLMs). SQuAI addresses key limitations of…

Information Retrieval · Computer Science 2025-10-20 Ines Besrour , Jingbo He , Tobias Schreieder , Michael Färber

Clinical decision making (CDM) is a complex, dynamic process crucial to healthcare delivery, yet it remains a significant challenge for artificial intelligence systems. While Large Language Model (LLM)-based agents have been tested on…

Computation and Language · Computer Science 2025-10-13 Jie Liu , Wenxuan Wang , Zizhan Ma , Guolin Huang , Yihang SU , Kao-Jung Chang , Wenting Chen , Haoliang Li , Linlin Shen , Michael Lyu

Clinical trials are critical for drug development. Constructing the appropriate eligibility criteria (i.e., the inclusion/exclusion criteria for patient recruitment) is essential for the trial's success. Proper design of clinical trial…

Computation and Language · Computer Science 2023-10-10 Zifeng Wang , Cao Xiao , Jimeng Sun

Medical conversational AI (AI) plays a pivotal role in the development of safer and more effective medical dialogue systems. However, existing benchmarks and evaluation frameworks for assessing the information-gathering and diagnostic…

Computation and Language · Computer Science 2026-01-08 Lecheng Gong , Weimin Fang , Ting Yang , Dongjie Tao , Chunxiao Guo , Peng Wei , Bo Xie , Jinqun Guan , Zixiao Chen , Fang Shi , Jinjie Gu , Junwei Liu

Systematic literature review is essential for evidence-based medicine, requiring comprehensive analysis of clinical trial publications. However, the application of artificial intelligence (AI) models for medical literature mining has been…

Objective: To assess the performance of the OpenAI GPT API in accurately and efficiently identifying relevant titles and abstracts from real-world clinical review datasets and compare its performance against ground truth labelling by two…

Computation and Language · Computer Science 2023-10-09 Eddie Guo , Mehul Gupta , Jiawen Deng , Ye-Jean Park , Mike Paget , Christopher Naugler

Life sciences research increasingly requires identifying, accessing, and effectively processing data from an ever-evolving array of information sources on the Linked Open Data (LOD) network. This dynamic landscape places a significant…

Information Retrieval · Computer Science 2025-06-24 Syed N. Sakib , Kallol Naha , Sajratul Y. Rubaiat , Hasan M. Jamil

Assessment of medication history-taking has traditionally relied on human observation, limiting scalability and detailed performance data. While Generative AI (GenAI) platforms enable extensive data collection and learning analytics provide…

Multimodal artificial intelligence (AI) systems have the potential to enhance clinical decision-making by interpreting various types of medical data. However, the effectiveness of these models across all medical fields is uncertain. Each…

Continuing advances in Large Language Models (LLMs) in artificial intelligence offer important capacities in intuitively accessing and using medical knowledge in many contexts, including education and training as well as assessment and…

Computation and Language · Computer Science 2024-08-01 Roma Shusterman , Allison C. Waters , Shannon O`Neill , Phan Luu , Don M. Tucker

Generative AI (GenAI) systems offer unprecedented opportunities for transforming professional and personal work, yet present challenges around prompting, evaluating and relying on outputs, and optimizing workflows. We argue that…

Human-Computer Interaction · Computer Science 2024-07-08 Lev Tankelevitch , Viktor Kewenig , Auste Simkute , Ava Elizabeth Scott , Advait Sarkar , Abigail Sellen , Sean Rintel

Chronic disease management requires regular adherence feedback to prevent avoidable hospitalizations, yet clinicians lack time to produce personalized patient communications. Manual authoring preserves clinical accuracy but does not scale;…

Human-Computer Interaction · Computer Science 2026-01-13 Xiaotian Zhang , Jinhong Yu , Pengwei Yan , Le Jiang , Xingyi Shen , Mumo Cheng , Xiaozhong Liu

Large Language Models (LLMs) are increasingly used for clinical decision support, where hallucinations and unsafe suggestions may pose direct risks to patient safety. These risks are hard to assess: subtle clinical errors are often missed…

Computation and Language · Computer Science 2026-05-14 Yinzhu Chen , Abdine Maiga , Hossein A. Rahmani , Emine Yilmaz

Clinical trials constitute a critical yet exceptionally challenging and costly stage of drug development (\$2.6B per drug), where protocols are encoded as complex natural language documents, motivating the use of AI systems beyond manual…

Artificial Intelligence · Computer Science 2026-04-06 Sixue Xing , Kerui Wu , Xuanye Xia , Meng Jiang , Jintai Chen , Tianfan Fu

Medical foundation models generate narrative explanations but cannot quantify intervention effects, detect evidence conflicts, or validate literature claims, limiting clinical auditability. We propose causal compilation, a paradigm that…

Artificial Intelligence · Computer Science 2026-02-24 Yulong Li , Jianxu Chen , Xiwei Liu , Chuanyue Suo , Rong Xia , Zhixiang Lu , Yichen Li , Xinlin Zhuang , Niranjana Arun Menon , Yutong Xie , Eran Segal , Imran Razzak

In this paper, we introduce the VerifAI project, a pioneering open-source scientific question-answering system, designed to provide answers that are not only referenced but also automatically vetted and verifiable. The components of the…

Computation and Language · Computer Science 2024-07-17 Adela Ljajić , Miloš Košprdić , Bojana Bašaragin , Darija Medvecki , Lorenzo Cassano , Nikola Milošević