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Online reinforcement learning (RL) algorithms offer great potential for personalizing treatment for participants in clinical trials. However, deploying an online, autonomous algorithm in the high-stakes healthcare setting makes quality…

Machine Learning · Computer Science 2024-08-13 Anna L. Trella , Kelly W. Zhang , Inbal Nahum-Shani , Vivek Shetty , Iris Yan , Finale Doshi-Velez , Susan A. Murphy

Personalization is very powerful in improving the effectiveness of health interventions. Reinforcement learning (RL) algorithms are suitable for learning these tailored interventions from sequential data collected about individuals.…

Artificial Intelligence · Computer Science 2020-05-22 Ali el Hassouni , Mark Hoogendoorn , Martijn van Otterlo , A. E. Eiben , Vesa Muhonen , Eduardo Barbaro

While reinforcement learning (RL) has proven to be the approach of choice for tackling many complex problems, it remains challenging to develop and deploy RL agents in real-life scenarios successfully. This paper presents pH-RL…

Artificial Intelligence · Computer Science 2021-04-01 Ali el Hassouni , Mark Hoogendoorn , Marketa Ciharova , Annet Kleiboer , Khadicha Amarti , Vesa Muhonen , Heleen Riper , A. E. Eiben

Reinforcement learning (RL) is a type of artificial intelligence for making optimal choices. In healthcare, researchers generally use offline RL (ORL), where models are trained and evaluated from retrospective observational data. To…

Machine Learning · Computer Science 2026-04-30 Thomas Frost , Hrisheekesh Vaidya , Steve Harris

As a paradigm for sequential decision making in unknown environments, reinforcement learning (RL) has received a flurry of attention in recent years. However, the explosion of model complexity in emerging applications and the presence of…

Machine Learning · Statistics 2025-07-22 Yuejie Chi , Yuxin Chen , Yuting Wei

Much attention has been devoted recently to the development of machine learning algorithms with the goal of improving treatment policies in healthcare. Reinforcement learning (RL) is a sub-field within machine learning that is concerned…

Imagine if AI decision-support tools not only complemented our ability to make accurate decisions, but also improved our skills, boosted collaboration, and elevated the joy we derive from our tasks. Despite the potential to optimize a broad…

Human-Computer Interaction · Computer Science 2024-04-16 Zana Buçinca , Siddharth Swaroop , Amanda E. Paluch , Susan A. Murphy , Krzysztof Z. Gajos

Reinforcement Learning (RL) has achieved state-of-the-art results in domains such as robotics and games. We build on this previous work by applying RL algorithms to a selection of canonical online stochastic optimization problems with a…

Motivated by the emerging needs of personalized preventative intervention in many healthcare applications, we consider a multi-stage, dynamic decision-making problem in the online setting with unknown model parameters. To deal with the…

Machine Learning · Computer Science 2022-11-17 Xinyun Chen , Pengyi Shi , Shanwen Pu

Online reinforcement learning (RL) algorithms are increasingly used to personalize digital interventions in the fields of mobile health and online education. Common challenges in designing and testing an RL algorithm in these settings…

Machine Learning · Computer Science 2022-09-01 Anna L. Trella , Kelly W. Zhang , Inbal Nahum-Shani , Vivek Shetty , Finale Doshi-Velez , Susan A. Murphy

Reinforcement learning (RL) requires skillful definition and remarkable computational efforts to solve optimization and control problems, which could impair its prospect. Introducing human guidance into reinforcement learning is a promising…

Machine Learning · Computer Science 2022-11-30 Jingda Wu , Zhiyu Huang , Wenhui Huang , Chen Lv

Dental disease is one of the most common chronic diseases despite being largely preventable. However, professional advice on optimal oral hygiene practices is often forgotten or abandoned by patients. Therefore patients may benefit from…

Artificial Intelligence · Computer Science 2022-09-15 Anna L. Trella , Kelly W. Zhang , Inbal Nahum-Shani , Vivek Shetty , Finale Doshi-Velez , Susan A. Murphy

In the rapidly changing healthcare landscape, the implementation of offline reinforcement learning (RL) in dynamic treatment regimes (DTRs) presents a mix of unprecedented opportunities and challenges. This position paper offers a critical…

Machine Learning · Computer Science 2024-06-05 Zhiyao Luo , Yangchen Pan , Peter Watkinson , Tingting Zhu

Reinforcement learning (RL) is concerned with how intelligence agents take actions in a given environment to maximize the cumulative reward they receive. In healthcare, applying RL algorithms could assist patients in improving their health…

Machine Learning · Statistics 2025-04-21 Chengchun Shi

Reinforcement learning (RL) has shown great promise with algorithms learning in environments with large state and action spaces purely from scalar reward signals. A crucial challenge for current deep RL algorithms is that they require a…

Machine Learning · Computer Science 2023-11-23 Shivakanth Sujit , Pedro H. M. Braga , Jorg Bornschein , Samira Ebrahimi Kahou

In recent years, reinforcement learning (RL) has acquired a prominent position in health-related sequential decision-making problems, gaining traction as a valuable tool for delivering adaptive interventions (AIs). However, in part due to a…

Machine Learning · Statistics 2024-07-16 Nina Deliu , Joseph Jay Williams , Bibhas Chakraborty

Reinforcement learning (RL) is a powerful machine learning technique that enables an intelligent agent to learn an optimal policy that maximizes the cumulative rewards in sequential decision making. Most of methods in the existing…

Machine Learning · Statistics 2023-01-06 Chengchun Shi , Zhengling Qi , Jianing Wang , Fan Zhou

Attention-based sequential recommendation methods have shown promise in accurately capturing users' evolving interests from their past interactions. Recent research has also explored the integration of reinforcement learning (RL) into these…

Machine Learning · Computer Science 2024-04-19 Melissa Mozifian , Tristan Sylvain , Dave Evans , Lili Meng

Reinforcement learning (RL) has achieved remarkable success in real-world decision-making across diverse domains, including gaming, robotics, online advertising, public health, and natural language processing. Despite these advances, a…

Applications · Statistics 2026-01-23 Asim H. Gazi , Yongyi Guo , Daiqi Gao , Ziping Xu , Kelly W. Zhang , Susan A. Murphy

Reinforcement learning (RL) has emerged as a powerful approach for tackling complex medical decision-making problems such as treatment planning, personalized medicine, and optimizing the scheduling of surgeries and appointments. It has…

Computation and Language · Computer Science 2023-10-31 Ying Liu , Haozhu Wang , Huixue Zhou , Mingchen Li , Yu Hou , Sicheng Zhou , Fang Wang , Rama Hoetzlein , Rui Zhang
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