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Surface Plasmon Resonance (SPR) offers a powerful tool for label-free and non-invasive characterization of biomolecular interactions. To date, several experimental configurations, based on two fundamental physical phenomena, e.g.,…

Optics · Physics 2022-11-15 Nishant Shukla , Pawan Chetri , Ratan Boruah , Ankur Gogoi , Gazi A Ahmed

Plasmonic sensing is an established technology for real-time biomedical diagnostics and air-quality monitoring. While intensity and wavelength tracking are the most commonly used interrogation methods for Surface Plasmon Resonance (SPR),…

Biosensors based on the principle of surface plasmon resonance (SPR) detection were used to measure biomolecular interactions in sarcomeres and changes of the dielectric constant of tubulin samples with varying concentration. At SPR,…

Quantum Physics · Physics 2015-06-26 Hans A. Schuessler , Alexander A. Kolomenskii , Andreas Mershin , D. V. Nanopoulos

In this paper we report a fiber optical sensor system based on surface plasmon resonance (SPR) with real-time response for biochemical interaction analysis. The fiber sensor is constructed from a multi-mode fiber with plastic cladding. To…

Applied Physics · Physics 2019-05-10 Zhixin Tan , Xuejin Li , Yuzhi Chen , Ping Fan

We present results from an instrument combining surface acoustic wave (SAW) propagation and surface plasmon resonance (SPR) measurements. The objective is to use two independent methods, the former based on adsorbed mass change measurements…

Soft Condensed Matter · Physics 2009-11-10 J. -M. Friedt , L. Francis , G. Reekmans , R. De Palma , A. Campitelli , U. B. Sleytr

Using the perturbation-response scanning (PRS) technique, we study a set of 23 proteins that display a variety of conformational motions upon ligand binding (e.g. shear, hinge, allosteric). In most cases, PRS determines residues that may be…

Biomolecules · Quantitative Biology 2015-05-18 C Atilgan , Z N Gerek , S B Ozkan , A R Atilgan

Microplastics are pervasive pollutants that pose threats to the environment and human health. Detecting them reliably represents a crucial step toward finding solutions. While traditional techniques like vibrational and mass spectroscopies…

Instrumentation and Detectors · Physics 2025-05-29 Natalia A. Gutierrez Andrade , Yunfeng Nie , Wendy Meulebroeck , Heidi Ottevaere

Surface plasmon resonance (SPR) chips are widely used to measure association and dissociation rates for the binding kinetics between two species of chemicals, e.g., cell receptors and ligands. It is commonly assumed that ligands are…

Quantitative Methods · Quantitative Biology 2016-12-07 Jacob Carroll , Matthew Raum , Kimberly Forsten-Williams , Uwe C. Täuber

The strong coupling of plasmonic resonance modes in conductive pyramidal nanoparticles leads to an increase in the density of free charges on the surface. By ensuring plasmonic coupling in the pyramidal nanoparticle lattice, the achieved…

A broadband detection method with coherent laser pulses exciting surface plasmons is investigated. The intensity and phase characteristics of the reflected light in Kretschmann configuration are calculated. It is shown that by mixing…

Instrumentation and Detectors · Physics 2018-11-14 Alexandre Kolomenskii , Elizabeth Surovic , Hans Schuessler

We show that for the optimized angle of incidence, the SPR based optical sensors exhibit dual resonance in the near-infrared region around which the sensor becomes exceptionally high sensitive. Both the resonances show opposite spectral…

Optics · Physics 2020-07-07 Indrajeet Kumar , Ranjeet Dwivedi , Saurabh Mani Tripathi

Surface Plasmon Resonance (SPR) is an important bio-sensing technique for real-time label-free detection. However, it is pivotal to optimize various parameters of the sensor configuration for efficient and highly sensitive sensing. To that…

Biological Physics · Physics 2020-07-20 Ehsan Kabir , Syed Mohammad Ashab Uddin , Sayeed Shafayet Chowdhury

Various metals (Ag, Al, Au, Bi, Cu), polymers (polyvinylpyrrolidone, polystyrene), and electrically conductive polymers (polyacetylene, polyaniline, poly(3,4-ethylenedioxythiophene) polystyrene sulfonate) were subjected to a particle swarm…

Optics · Physics 2017-02-23 Casey Kneale , Karl S. Booksh

Surface plasmon resonance (SPR) is generally observed by excitation of surface plasmon polaritons on the metal (Au/Ag) surface. In order to utilize the SPR phenomenon for sensing application, the metal surface is functionalized with…

Optics · Physics 2022-12-20 Amrit Kumar , Manjuladevi V , R. K. Gupta

This review explores the evolution of Surface Plasmon Resonance (SPR) spectroscopy and sensing, transitioning from fundamental studies of adsorption-desorption kinetics to the sophisticated sensing with Electropolymerized Molecularly…

Materials Science · Physics 2026-02-24 Rigoberto Advincula , Jihua Chen

A mirrored bilayer structure incorporating layers of Graphene and MoS2 is proposed here for Surface Plasmon Resonance (SPR) biosensing and its performance is evaluated numerically. Starting from the basic configuration, the structure with…

Optics · Physics 2020-02-10 Sayeed Shafayet Chowdhury , Syed Mohammad Ashab Uddin

Sensors based on the phenomenon of surface plasmon resonance have limited sensitivity, up to 123 degree/Refractive Index Unit, which restricts their applicability in detecting subtle changes gin biological media (around 10-5 RIU). To…

Optics · Physics 2026-01-12 Rostyslav Terekhov , Zoya Eremenko , Sergii Kulish

With recent advances in scanning probe microscopy (SPM), it is now routine to determine the atomic structure of surfaces and molecules while quantifying the local tip-sample interaction potentials. Such quantitative experiments are based on…

Applied Physics · Physics 2018-12-24 Omur E. Dagdeviren , Yoichi Miyahara , Aaron Mascaro , Tyler Enright , Peter Grütter

We present here an experimental set-up to perform simultaneously measurements of surface plasmon resonance (SPR) and X-ray absorption spectroscopy (XAS) in a synchrotron beamline. The system allows measuring in situ and in real time the…

Instrumentation and Detectors · Physics 2015-06-04 A. Serrano , O. Rodríguez de la Fuente , V. Collado , J. Rubio-Zuazo , C. Monton , G. Castro , M. A. García

In this paper the angular characteristics of a multimode fiber SPR sensor are theoretically investigated. By separating the contributions of beams incident at different angles, a compact model is presented to predict the shift of the…

Optics · Physics 2015-11-13 Zhixin Tan , Xin Hao , Xuejin Li , Yuzhi Chen , Xueming Hong , Ping Fan
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