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We describe a simple conductance-based model neuron that includes intra- and extra-cellular ion concentration dynamics and show that this model exhibits periodic bursting. The bursting arises as the fast spiking behavior of the neuron is…

Cell Behavior · Quantitative Biology 2011-09-22 Ernest Barreto , John R. Cressman

In a multiscale modeling approach, we present computer simulation results for a rectifying bipolar nanopore on two modeling levels. In an all-atom model, we use explicit water to simulate ion transport directly with the molecular dynamics…

Mesoscale and Nanoscale Physics · Physics 2018-03-13 Zoltán Ható , Mónika Valiskó , Tamás Kristóf , Dirk Gillespie , Dezső Boda

The brain's remarkable and efficient information processing capability is driving research into brain-inspired (neuromorphic) computing paradigms. Artificial aqueous ion channels are emerging as an exciting platform for neuromorphic…

Soft Condensed Matter · Physics 2024-04-26 T. M. Kamsma , J. Kim , K. Kim , W. Q. Boon , C. Spitoni , J. Park , R. van Roij

In recent years, there have been a surge in applications of neural networks (NNs) in physical sciences. Although various algorithmic advances have been proposed, there are, thus far, limited number of studies that assess the…

Fluid Dynamics · Physics 2020-12-17 Kai Fukami , Romit Maulik , Nesar Ramachandra , Koji Fukagata , Kunihiko Taira

The calculation of thermodynamic properties of biochemical systems typically requires the use of resource-intensive molecular simulation methods. One example thereof is the thermodynamic profiling of hydration sites, i.e. high-probability…

Biomolecules · Quantitative Biology 2020-01-08 Ahmadreza Ghanbarpour , Amr H. Mahmoud , Markus A. Lill

There has been tremendous experimental progress in the last decade in identifying the structure and function of biological pores (ion channels) and fabricating synthetic pores. Despite this progress, many questions still remain about the…

Soft Condensed Matter · Physics 2015-03-17 Michael Zwolak , James Wilson , Massimiliano Di Ventra

Molecular dynamics simulations have been extensively used to predict thermal properties, but simulating different phases with similar precision using a unified force field is often difficult, due to the lack of accurate and transferrable…

Materials Science · Physics 2019-12-12 Ruiyang Li , Eungkyu Lee , Tengfei Luo

Neural network test cases are meant to exercise different reasoning paths in an architecture and used to validate the prediction outcomes. In this paper, we introduce "computational profiles" as vectors of neuron activation levels. We…

Machine Learning · Computer Science 2021-07-30 Ettore Merlo , Mira Marhaba , Foutse Khomh , Houssem Ben Braiek , Giuliano Antoniol

Understanding ion-transport under molecular confinement is essential for developing next-generation energy technologies, where ionic motion often occurs within nanoscale or angstrom-scale channels. In this study, we use the model system of…

Tensile tests at room temperature are performed using molecular dynamics on all configurations of single-walled carbon nanotubes up to 4 nm in diameter. Distributions of the Young's modulus, Poisson's ratio, ultimate tensile strength and…

Applied Physics · Physics 2021-09-08 Marko Canadija

In this paper, a new methodology is proposed that allows for the low-complexity development of neural network (NN) based equalizers for the mitigation of impairments in high-speed coherent optical transmission systems. In this work, we…

The simulation of nanophotonic structures relies on electromagnetic solvers, which play a crucial role in understanding their behavior. However, these solvers often come with a significant computational cost, making their application in…

Machine Learning · Computer Science 2024-05-22 Liang Cheng , Prashant Singh , Francesco Ferranti

A novel convolution neural network model, abbreviated NL-CNN is proposed, where nonlinear convolution is emulated in a cascade of convolution + nonlinearity layers. The code for its implementation and some trained models are made publicly…

Machine Learning · Computer Science 2021-02-03 Radu Dogaru , Ioana Dogaru

This paper studies mechanism of preconcentration of charged particles in a straight micro-channel embedded with permselective membranes, by numerically solving coupled transport equations of ions, charged particles and solvent fluid without…

Fluid Dynamics · Physics 2018-02-14 Zirui Li , Wei Liu , Yudan Zhu , Xiaohua Lu , Yuantong Gu , Jongyoon Han

We train a deep convolutional neural network to predict hydrodynamic results for flow coefficients, average transverse momenta and charged particle multiplicities in ultrarelativistic heavy-ion collisions from the initial energy density…

High Energy Physics - Phenomenology · Physics 2023-03-09 H. Hirvonen , K. J. Eskola , H. Niemi

Ion distribution in aqueous electrolytes near the interface plays critical roles in electrochemical, biological and colloidal systems and is expected to be particularly significant inside nanoconfined regions. Electroneutrality of the total…

Soft Condensed Matter · Physics 2015-03-03 Zhi-Xiang Luo , Yun-Zhao Xing , Yan-Chun Ling , Alfred Kleinhammes , Yue Wu

Neural network (NN) interatomic potentials provide fast prediction of potential energy surfaces, closely matching the accuracy of the electronic structure methods used to produce the training data. However, NN predictions are only reliable…

Machine Learning · Computer Science 2021-08-31 Daniel Schwalbe-Koda , Aik Rui Tan , Rafael Gómez-Bombarelli

Machine learning algorithms have recently been considered for many tasks in the field of wireless communications. Previously, we have proposed the use of a deep fully convolutional neural network (CNN) for receiver processing and shown it…

Signal Processing · Electrical Eng. & Systems 2022-07-13 Janne M. J. Huttunen , Dani Korpi , Mikko Honkala

Neural networks have been notorious for being computationally expensive. This is mainly because neural networks are often over-parametrized and most likely have redundant nodes or layers as they are getting deeper and wider. Their demand…

Computer Vision and Pattern Recognition · Computer Science 2019-10-08 Georgios Tzelepis , Ahraz Asif , Saimir Baci , Selcuk Cavdar , Eren Erdal Aksoy

We consider whether deep convolutional networks (CNNs) can represent decision functions with similar accuracy as recurrent networks such as LSTMs. First, we show that a deep CNN with an architecture inspired by the models recently…