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Diffusion models have shown impressive performance for generative modelling of images. In this paper, we present a novel semantic segmentation method based on diffusion models. By modifying the training and sampling scheme, we show that…

Computer Vision and Pattern Recognition · Computer Science 2021-12-28 Julia Wolleb , Robin Sandkühler , Florentin Bieder , Philippe Valmaggia , Philippe C. Cattin

Diffusion models have enabled remarkably high-quality medical image generation, yet it is challenging to enforce anatomical constraints in generated images. To this end, we propose a diffusion model-based method that supports…

Image and Video Processing · Electrical Eng. & Systems 2024-06-21 Nicholas Konz , Yuwen Chen , Haoyu Dong , Maciej A. Mazurowski

Annotation variability remains a substantial challenge in medical image segmentation, stemming from ambiguous imaging boundaries and diverse clinical expertise. Traditional deep learning methods producing single deterministic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Han Zhang , Xiangde Luo , Yong Chen , Kang Li

A major challenge in the segmentation of medical images is the large inter- and intra-observer variability in annotations provided by multiple experts. To address this challenge, we propose a novel method for multi-expert prediction using…

Image and Video Processing · Electrical Eng. & Systems 2023-06-16 Tomer Amit , Shmuel Shichrur , Tal Shaharabany , Lior Wolf

Medical image segmentation is crucial for accurate clinical diagnoses, yet it faces challenges such as low contrast between lesions and normal tissues, unclear boundaries, and high variability across patients. Deep learning has improved…

Image and Video Processing · Electrical Eng. & Systems 2024-12-09 Houze Liu , Tong Zhou , Yanlin Xiang , Aoran Shen , Jiacheng Hu , Junliang Du

Medical image segmentation models struggle with rare abnormalities due to scarce annotated pathological data. We propose DiffAug a novel framework that combines textguided diffusion-based generation with automatic segmentation validation to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Maham Nazir , Muhammad Aqeel , Francesco Setti

Medical image segmentation is crucial for clinical diagnosis and treatment planning. Traditional methods typically produce a single segmentation mask, failing to capture inherent uncertainty. Recent generative models enable the creation of…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Huynh Trinh Ngoc , Toan Nguyen Hai , Ba Luong Son , Long Tran Quoc

Denoising Diffusion Probabilistic models have become increasingly popular due to their ability to offer probabilistic modeling and generate diverse outputs. This versatility inspired their adaptation for image segmentation, where multiple…

Diffusion Probabilistic Methods are employed for state-of-the-art image generation. In this work, we present a method for extending such models for performing image segmentation. The method learns end-to-end, without relying on a…

Computer Vision and Pattern Recognition · Computer Science 2022-09-08 Tomer Amit , Tal Shaharbany , Eliya Nachmani , Lior Wolf

In medical image segmentation tasks, diffusion models have shown significant potential. However, mainstream diffusion models suffer from drawbacks such as multiple sampling times and slow prediction results. Recently, consistency models, as…

Computer Vision and Pattern Recognition · Computer Science 2024-05-16 Kejia Zhang , Lan Zhang , Haiwei Pan , Baolong Yu

Large-scale, big-variant, high-quality data are crucial for developing robust and successful deep-learning models for medical applications since they potentially enable better generalization performance and avoid overfitting. However, the…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Zheyuan Zhang , Lanhong Yao , Bin Wang , Debesh Jha , Gorkem Durak , Elif Keles , Alpay Medetalibeyoglu , Ulas Bagci

Medical image segmentation often involves inherent uncertainty due to variations in expert annotations. Capturing this uncertainty is an important goal and previous works have used various generative image models for the purpose of…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Jakob Lønborg Christensen , Morten Rieger Hannemose , Anders Bjorholm Dahl , Vedrana Andersen Dahl

Diffusion Probabilistic Models have recently shown remarkable performance in generative image modeling, attracting significant attention in the computer vision community. However, while a substantial amount of diffusion-based research has…

Computer Vision and Pattern Recognition · Computer Science 2023-07-12 Yijun Yang , Huazhu Fu , Angelica I. Aviles-Rivero , Carola-Bibiane Schönlieb , Lei Zhu

We introduce Mediffusion -- a new method for semi-supervised learning with explainable classification based on a joint diffusion model. The medical imaging domain faces unique challenges due to scarce data labelling -- insufficient for…

Computer Vision and Pattern Recognition · Computer Science 2024-11-15 Joanna Kaleta , Paweł Skierś , Jan Dubiński , Przemysław Korzeniowski , Kamil Deja

Quantifying aleatoric uncertainty in medical image segmentation is critical since it is a reflection of the natural variability observed among expert annotators. A conventional approach is to model the segmentation distribution using the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Phi Van Nguyen , Ngoc Huynh Trinh , Duy Minh Lam Nguyen , Phu Loc Nguyen , Quoc Long Tran

Diffusion models have shown impressive performance for image generation, often times outperforming other generative models. Since their introduction, researchers have extended the powerful noise-to-image denoising pipeline to discriminative…

Image and Video Processing · Electrical Eng. & Systems 2023-12-21 Fahim Ahmed Zaman , Mathews Jacob , Amanda Chang , Kan Liu , Milan Sonka , Xiaodong Wu

Accurate segmentation of brain tumors in MRI scans is essential for reliable clinical diagnosis and effective treatment planning. Recently, diffusion models have demonstrated remarkable effectiveness in image generation and segmentation…

Image and Video Processing · Electrical Eng. & Systems 2025-07-31 Sara Yavari , Rahul Nitin Pandya , Jacob Furst

Accurate medical image segmentation is crucial for precise anatomical delineation. Deep learning models like U-Net have shown great success but depend heavily on large datasets and struggle with domain shifts, complex structures, and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Hantao Zhang , Yuhe Liu , Jiancheng Yang , Weidong Guo , Xinyuan Wang , Pascal Fua

Medical image data is less accessible than in other domains due to privacy and regulatory constraints. In addition, labeling requires costly, time-intensive manual image annotation by clinical experts. To overcome these challenges,…

Image and Video Processing · Electrical Eng. & Systems 2025-07-11 Fangyijie Wang , Kevin Whelan , Félix Balado , Kathleen M. Curran , Guénolé Silvestre

Recent advances in deep learning have shown that learning robust feature representations is critical for the success of many computer vision tasks, including medical image segmentation. In particular, both transformer and…

Computer Vision and Pattern Recognition · Computer Science 2025-02-03 David Li , Anvar Kurmukov , Mikhail Goncharov , Roman Sokolov , Mikhail Belyaev
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