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Related papers: A Framework for Understanding Selection Bias in Re…

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Electronic health records (EHRs) are increasingly recognized as a cost-effective resource for patient recruitment in clinical research. However, how to optimally select a cohort from millions of individuals to answer a scientific question…

Methodology · Statistics 2023-12-14 Guanghao Zhang , Lauren J. Beesley , Bhramar Mukherjee , Xu Shi

Estimating the causal effect of a treatment or health policy with observational data can be challenging due to an imbalance of and a lack of overlap between treated and control covariate distributions. In the presence of limited overlap,…

Methodology · Statistics 2025-03-24 Martha Barnard , Jared D. Huling , Julian Wolfson

Algorithms and technologies are essential tools that pervade all aspects of our daily lives. In the last decades, health care research benefited from new computer-based recruiting methods, the use of federated architectures for data…

Computers and Society · Computer Science 2023-01-26 Chiara Criscuolo , Tommaso Dolci , Mattia Salnitri

Objective Electronic health records (EHRs) are a promising source of data for health outcomes research in oncology. A challenge in using EHR data is that selecting cohorts of patients often requires information in unstructured parts of the…

Objectives: Leveraging artificial intelligence (AI) in conjunction with electronic health records (EHRs) holds transformative potential to improve healthcare. Yet, addressing bias in AI, which risks worsening healthcare disparities, cannot…

Artificial Intelligence · Computer Science 2026-01-08 Feng Chen , Liqin Wang , Julie Hong , Jiaqi Jiang , Li Zhou

The adoption of diagnosis and prognostic algorithms in healthcare has led to concerns about the perpetuation of bias against disadvantaged groups of individuals. Deep learning methods to detect and mitigate bias have revolved around…

With the universal adoption of machine learning in healthcare, the potential for the automation of societal biases to further exacerbate health disparities poses a significant risk. We explore algorithmic fairness from the perspective of…

Machine Learning · Computer Science 2024-04-02 Md Rahat Shahriar Zawad , Peter Washington

Selection bias can hinder accurate estimation of association parameters in binary disease risk models using non-probability samples like electronic health records (EHRs). The issue is compounded when participants are recruited from multiple…

The collection of large, complex datasets has become common across a wide variety of domains. Visual analytics tools increasingly play a key role in exploring and answering complex questions about these large datasets. However, many…

Human-Computer Interaction · Computer Science 2020-06-19 David Borland , Wenyuan Wang , Jonathan Zhang , Joshua Shrestha , David Gotz

Statistical learning with a large number of rare binary features is commonly encountered in analyzing electronic health records (EHR) data, especially in the modeling of disease onset with prior medical diagnoses and procedures. Dealing…

Machine Learning · Computer Science 2024-02-28 Jianmin Chen , Robert H. Aseltine , Fei Wang , Kun Chen

Clinical trials with a hybrid control arm (a control arm constructed from a combination of randomized patients and real-world data on patients receiving usual care in standard clinical practice) have the potential to decrease the cost of…

Methodology · Statistics 2021-08-20 Joanna Harton , Brian Segal , Ronac Mamtani , Nandita Mitra , Rebecca Hubbard

We propose a novel definition of selection bias in analytic epidemiology using potential outcomes. This definition captures selection bias under both the structural approach (where conditioning on selection into the study opens a noncausal…

Methodology · Statistics 2023-10-24 Eben Kenah

Over the last decades, many prognostic models based on artificial intelligence techniques have been used to provide detailed predictions in healthcare. Unfortunately, the real-world observational data used to train and validate these models…

Machine Learning · Computer Science 2023-11-21 Alice Bernasconi , Alessio Zanga , Peter J. F. Lucas , Marco Scutari , Fabio Stella

Electronic Health Records (EHR) have revolutionized healthcare by digitizing patient data, improving accessibility, and streamlining clinical workflows. However, extracting meaningful insights from these complex and multimodal datasets…

Artificial Intelligence · Computer Science 2025-10-27 Naama Kashani , Mira Cohen , Uri Shaham

The use of Electronic Health Records (EHRs) has increased dramatically in the past 15 years, as, it is considered an important source of managing data od patients. The EHRs are primary sources of disease diagnosis and demographic data of…

Machine Learning · Computer Science 2024-04-02 Bushra F. Alsaqer , Alaa F. Alsaqer , Amna Asif

Biomedical studies that use electronic health records (EHR) data for inference are often subject to bias due to measurement error. The measurement error present in EHR data is typically complex, consisting of errors of unknown functional…

Methodology · Statistics 2020-06-16 Eric J. Oh , Bryan E. Shepherd , Thomas Lumley , Pamela A. Shaw

Accurate predictions, as with machine learning, may not suffice to provide optimal healthcare for every patient. Indeed, prediction can be driven by shortcuts in the data, such as racial biases. Causal thinking is needed for data-driven…

Selection bias arises when the probability that an observation enters a dataset depends on variables related to the quantities of interest, leading to systematic distortions in estimation and uncertainty quantification. For example, in…

Electronic health records (EHR's) are only a first step in capturing and utilizing health-related data - the problem is turning that data into useful information. Models produced via data mining and predictive analysis profile inherited…

Databases · Computer Science 2011-12-08 Casey Bennett , Thomas Doub

Many Artificial Intelligence systems depend on the agent's updating its beliefs about the world on the basis of experience. Experiments constitute one type of experience, so scientific methodology offers a natural environment for examining…

Artificial Intelligence · Computer Science 2013-04-08 Harold P. Lehmann
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