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Related papers: Epidemic Control on a Large-Scale-Agent-Based Epid…

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We introduce a policy model coupled with the susceptible-infected-recovered (SIR) epidemic model to study interactions between policy-making and the dynamics of epidemics. We consider both single-region policies, as well as game-theoretic…

Optimization and Control · Mathematics 2024-08-06 Xia Li , Andrea L. Bertozzi , P. Jeffrey Brantingham , Yevgeniy Vorobeychik

Recent Covid-19 pandemic has demonstrated the need of efficient epidemic outbreak management. We study the optimal control problem of minimizing the fraction of infected population by applying vaccination and treatment control strategies,…

Social and Information Networks · Computer Science 2021-12-07 Jagtap Kalyani Devendra , Kundan Kandhway

As a common strategy of contagious disease containment, lockdowns will inevitably weaken the economy. The ongoing COVID-19 pandemic underscores the trade-off arising from public health and economic cost. An optimal lockdown policy to…

Optimization and Control · Mathematics 2022-01-26 Qianqian Ma , Yang-Yu Liu , Alex Olshevsky

When effective medical treatment and vaccination are not available, non-pharmaceutical interventions such as social distancing, home quarantine and far-reaching shutdown of public life are the only available strategies to prevent the spread…

Populations and Evolution · Quantitative Biology 2020-08-19 Markus Kantner , Thomas Koprucki

In this research paper we modify a classical SIR model to better adapt to the dynamics of COVID-19, that is we propose the heterogeneous SQAIRD model where COVID-19 spreads over a population of economic agents, namely: the elderly, adults…

Optimization and Control · Mathematics 2021-05-19 Elena Gubar , Laura Policardo , Edgar J. Sanchez Carrera , Vladislav Taynitskiy

Effective epidemic control is crucial for mitigating the spread of infectious diseases, particularly when pharmaceutical interventions such as vaccines or treatments are limited. Non-pharmaceutical strategies, including mobility…

Physics and Society · Physics 2025-12-03 Deborah Volpe , Giacomo Orlandi , Mattia Boggio , Carlo Novara , Lorenzo Zino , Giovanna Turvani

We study an optimal control problem where the objective is to find the best vaccine allocation during an epidemic outbreak. The epidemic dynamics is described by an age-structured SIR model with nonlocal interactions. Both the infection and…

Optimization and Control · Mathematics 2026-05-19 Luís Almeida , Romain Ducasse , Elisa Paparelli

The relationship between epidemiology, mathematical modeling and computational tools allows to build and test theories on the development and battling of a disease. This PhD thesis is motivated by the study of epidemiological models applied…

Optimization and Control · Mathematics 2014-01-30 Helena Sofia Rodrigues

Lane change is a challenging task which requires delicate actions to ensure safety and comfort. Some recent studies have attempted to solve the lane-change control problem with Reinforcement Learning (RL), yet the action is confined to…

Robotics · Computer Science 2019-06-07 Pin Wang , Hanhan Li , Ching-Yao Chan

We study the problem of a policymaker who aims at taming the spread of an epidemic while minimizing its associated social costs. The main feature of our model lies in the fact that the disease's transmission rate is a diffusive stochastic…

Optimization and Control · Mathematics 2020-11-04 Salvatore Federico , Giorgio Ferrari

Reinforcement learning algorithms such as the deep deterministic policy gradient algorithm (DDPG) has been widely used in continuous control tasks. However, the model-free DDPG algorithm suffers from high sample complexity. In this paper we…

Machine Learning · Computer Science 2019-11-14 Qingpeng Cai , Ling Pan , Pingzhong Tang

We analyze an optimal control version of a simple SIR epidemiology model that includes a partially specified vaccination policy and takes into account fatigue from protracted application of social distancing measures. The model assumes…

Populations and Evolution · Quantitative Biology 2021-08-17 Evangelos F. Magirou

Since early 2020, the world has been dealing with a raging pandemic outbreak: COVID-19. A year later, vaccines have become accessible, but in limited quantities, so that governments needed to devise a strategy to decide which part of the…

Populations and Evolution · Quantitative Biology 2022-04-13 Sander Tonkens , Paul de Klaver , Mauro Salazar

Whenever countries are threatened by a pandemic, as is the case with the COVID-19 virus, governments should take the right actions to safeguard public health as well as to mitigate the negative effects on the economy. In this regard, there…

Machine Learning · Computer Science 2020-05-18 Luis Miralles-Pechuán , Fernando Jiménez , Hiram Ponce , Lourdes Martínez-Villaseñor

Deep Reinforcement Learning (DRL) techniques have received significant attention in control and decision-making algorithms. Most applications involve complex decision-making systems, justified by the algorithms' computational power and…

Systems and Control · Electrical Eng. & Systems 2024-02-28 Fatemeh Tavakkoli , Pouria Sarhadi , Benoit Clement , Wasif Naeem

A crucial aspect of managing a public health crisis is to effectively balance prevention and mitigation strategies, while taking their socio-economic impact into account. In particular, determining the influence of different…

The COVID-19 pandemic has posed a policy making crisis where efforts to slow down or end the pandemic conflict with economic priorities. This paper provides mathematical analysis of optimal disease control policies with idealized…

Optimization and Control · Mathematics 2021-02-16 Aaron Z. Palmer , Zelda B. Zabinsky , Shan Liu

Designing effective strategies for controlling epidemic spread by vaccination is an important question in epidemiology, especially in the early stages when vaccines are limited. This is a challenging question when the contact network is…

Data Structures and Algorithms · Computer Science 2025-06-03 Dung Nguyen , Aravind Srinivasan , Renata Valieva , Anil Vullikanti , Jiayi Wu

The year 2020 has seen the COVID-19 virus lead to one of the worst global pandemics in history. As a result, governments around the world are faced with the challenge of protecting public health, while keeping the economy running to the…

Machine Learning · Computer Science 2020-10-22 Varun Kompella , Roberto Capobianco , Stacy Jong , Jonathan Browne , Spencer Fox , Lauren Meyers , Peter Wurman , Peter Stone

Policy gradient (PG) methods are successful approaches to deal with continuous reinforcement learning (RL) problems. They learn stochastic parametric (hyper)policies by either exploring in the space of actions or in the space of parameters.…

Machine Learning · Computer Science 2024-05-31 Alessandro Montenegro , Marco Mussi , Alberto Maria Metelli , Matteo Papini