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Poly-PL kinetic systems (PYK) are kinetic systems consisting of nonnegative linear combinations of power law functions. In this contribution, we analyze these kinetic systems using two main approaches: (1) we define a canonical power law…

Dynamical Systems · Mathematics 2021-12-24 Editha C. Jose , Eduardo R. Mendoza , Dylan Antonio SJ. Talabis

A frequently desirable characteristic of chemical kinetics systems is that of persistence, the property that if all the species are initially present then none of them may tend toward extinction. It is known that solutions of…

Dynamical Systems · Mathematics 2014-07-15 Matthew D. Johnston , David Siegel

Absolute concentration robustness (ACR) and concordance are novel concepts in the theory of robustness and stability within Chemical Reaction Network Theory. In this paper, we have extended Shinar and Feinberg's reaction network analysis…

Molecular Networks · Quantitative Biology 2022-09-14 Patrick Vincent N. Lubenia , Eduardo R. Mendoza , Angelyn R. Lao

It is well known that, for mass-action systems, complex-balanced equilibria are asymptotically stable. For generalized mass-action systems, even if there exists a unique complex-balanced equilibrium (in every stoichiometric class and for…

Dynamical Systems · Mathematics 2022-09-14 Balazs Boros , Stefan Müller , Georg Regensburger

Generalized mass-action systems are power-law dynamical systems arising from chemical reaction networks. Essentially, every nonnegative ODE model used in chemistry and biology (for example, in ecology and epidemiology) and even in economics…

Dynamical Systems · Mathematics 2023-11-21 Stefan Müller , Georg Regensburger

A policy is said to be robust if it maximizes the reward while considering a bad, or even adversarial, model. In this work we formalize two new criteria of robustness to action uncertainty. Specifically, we consider two scenarios in which…

Machine Learning · Computer Science 2019-05-08 Chen Tessler , Yonathan Efroni , Shie Mannor

Adaptive cruise control systems are fundamental components of the automation of the driving. At upper control level, ACC systems are based on car-following models determining the acceleration rate of a vehicle according to the distance gap…

Physics and Society · Physics 2020-04-13 Antoine Tordeux , Jean-Patrick Lebacque , Sylvain Lassarre

In this paper we show that the dynamics of a class of kinetic compartmental models with bounded capacities, monotone reaction rates and a strongly connected interconnection structure is persistent. The result is based on the chemical…

Dynamical Systems · Mathematics 2022-01-25 G. Szederkenyi , B. Acs , Gy. Liptak , M. A. Vaghy

This paper addresses a fundamental and important question in control: under what conditions does there fail to exist a robust control policy that keeps the state of a constrained linear system within a target set, despite bounded…

Systems and Control · Electrical Eng. & Systems 2025-07-08 Paul Trodden , José M. Maestre , Hideaki Ishii

Considering the control problem for nonlinear uncertain systems, the tolerable range of uncertain control input gain is a fundamental issue. The paper presents the necessary and sufficient condition for the well-performed closed-loop system…

Systems and Control · Electrical Eng. & Systems 2020-06-23 Sen Chen , Yi Huang , Zhi-liang Zhao

Living systems are forced away from thermodynamic equilibrium by exchange of mass and energy with their environment. In order to model a biochemical reaction network in a non-equilibrium state one requires a mathematical formulation to…

Molecular Networks · Quantitative Biology 2012-02-21 Ronan M. T. Fleming , Ines Thiele

This paper studies the relations among system parameters, uniqueness, and stability of equilibria, for kinetic systems given in the form of polynomial ODEs. Such models are commonly used to describe the dynamics of nonnegative systems, with…

Molecular Networks · Quantitative Biology 2016-11-14 Antonio A. Alonso , Gabor Szederkenyi

Poly-PL kinetic systems are kinetic systems consisting of nonnegative linear combinations of power law functions. In this contribution, we analyze these kinetic systems using two main approaches: (1) we define a canonical power law…

Dynamical Systems · Mathematics 2021-07-13 Noel T. Fortun , Dylan Antonio SJ. Talabis , Editha C. Jose , Eduardo R. Mendoza

The Turing completeness of continuous Chemical Reaction Networks (CRNs) states that any computable real function can be computed by a continuous CRN on a finite set of molecular species, possibly restricted to elementary reactions, i.e.…

Quantitative Methods · Quantitative Biology 2023-10-24 Mathieu Hemery , François Fages

Cellular Automata (CA) are a class of discrete dynamical systems that have been widely used to model complex systems in which the dynamics is specified at local cell-scale. Classically, CA are run on a regular lattice and with perfect…

Cellular Automata and Lattice Gases · Physics 2007-05-23 Nazim A. Fates , Michel Morvan

Biochemical covalent modification networks exhibit a remarkable suite of steady state and dynamical properties such as multistationarity, oscillations, ultrasensitivity and absolute concentration robustness. This paper focuses on conditions…

Molecular Networks · Quantitative Biology 2024-02-29 Badal Joshi , Tung D. Nguyen

Many-body systems relaxing to equilibrium can exhibit complex dynamics even if their steady state is trivial. At low temperatures or high densities their evolution is often dominated by steric hindrances affecting particle motion [1,2,3].…

Statistical Mechanics · Physics 2016-05-10 M. M. Valado , C. Simonelli , M. D. Hoogerland , I. Lesanovsky , J. P. Garrahan , E. Arimondo , D. Ciampini , O. Morsch

We present conditions which guarantee a parametrization of the set of positive equilibria of a generalized mass-action system. Our main results state that (i) if the underlying generalized chemical reaction network has an effective…

Dynamical Systems · Mathematics 2018-05-24 Matthew D. Johnston , Stefan Müller , Casian Pantea

Robustness is an observable property for which a chemical reaction network (CRN) can maintain its functionalities despite the influence of different perturbations. In general, to verify whether a network is robust, it is necessary to…

Formal Languages and Automata Theory · Computer Science 2021-04-29 Lucia Nasti , Roberta Gori , Paolo Milazzo

The AC frequency in electrical power systems is conventionally regulated by synchronous machines. The gradual replacement of these machines by asynchronous renewable-based generation, which provides little or no frequency control, increases…

Optimization and Control · Mathematics 2019-06-13 Richard Pates , Enrique Mallada