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Multi-task learning is central to many real-world applications. Unfortunately, obtaining labelled data for all tasks is time-consuming, challenging, and expensive. Active Learning (AL) can be used to reduce this burden. Existing techniques…

Computer Vision and Pattern Recognition · Computer Science 2022-11-22 Nikita Durasov , Nik Dorndorf , Pascal Fua

Multiple instance learning (MIL) is a powerful tool to solve the weakly supervised classification in whole slide image (WSI) based pathology diagnosis. However, the current MIL methods are usually based on independent and identical…

Computer Vision and Pattern Recognition · Computer Science 2021-11-02 Zhuchen Shao , Hao Bian , Yang Chen , Yifeng Wang , Jian Zhang , Xiangyang Ji , Yongbing Zhang

Weak supervision learning on classification labels has demonstrated high performance in various tasks, while a few pixel-level fine annotations are also affordable. Naturally a question comes to us that whether the combination of…

Computer Vision and Pattern Recognition · Computer Science 2021-10-26 Jiahui Li , Wen Chen , Xiaodi Huang , Zhiqiang Hu , Qi Duan , Hongsheng Li , Dimitris N. Metaxas , Shaoting Zhang

Domain adaptation (DA) is a representation learning methodology that transfers knowledge from a label-sufficient source domain to a label-scarce target domain. While most of early methods are focused on unsupervised DA (UDA), several…

Computer Vision and Pattern Recognition · Computer Science 2021-04-02 Yoonhyung Kim , Changick Kim

Multiple instance learning (MIL) is a key algorithm for classification of whole slide images (WSI). Histology WSIs can have billions of pixels, which create enormous computational and annotation challenges. Typically, such images are…

Image and Video Processing · Electrical Eng. & Systems 2021-11-03 Andriy Myronenko , Ziyue Xu , Dong Yang , Holger Roth , Daguang Xu

Deep learning based medical image diagnosis has shown great potential in clinical medicine. However, it often suffers two major difficulties in practice: 1) only limited labeled samples are available due to expensive annotation costs over…

Machine Learning · Computer Science 2019-11-19 Yifan Zhang , Ying Wei , Peilin Zhao , Shuaicheng Niu , Qingyao Wu , Mingkui Tan , Junzhou Huang

Pathology detection and delineation enables the automatic interpretation of medical scans such as chest X-rays while providing a high level of explainability to support radiologists in making informed decisions. However, annotating…

Computer Vision and Pattern Recognition · Computer Science 2023-09-07 Philip Müller , Felix Meissen , Johannes Brandt , Georgios Kaissis , Daniel Rueckert

Histopathological images provide rich information for disease diagnosis. Large numbers of histopathological images have been digitized into high resolution whole slide images, opening opportunities in developing computational image analysis…

Image and Video Processing · Electrical Eng. & Systems 2020-11-06 Jiayun Li , Wenyuan Li , Anthony Sisk , Huihui Ye , W. Dean Wallace , William Speier , Corey W. Arnold

Deep learning based object detectors struggle generalizing to a new target domain bearing significant variations in object and background. Most current methods align domains by using image or instance-level adversarial feature alignment.…

Computer Vision and Pattern Recognition · Computer Science 2023-11-10 Muhammad Akhtar Munir , Muhammad Haris Khan , M. Saquib Sarfraz , Mohsen Ali

Image segmentation methods are usually trained with pixel-level annotations, which require significant human effort to collect. The most common solution to address this constraint is to implement weakly-supervised pipelines trained with…

Computer Vision and Pattern Recognition · Computer Science 2020-08-26 Miriam Bellver , Amaia Salvador , Jordi Torres , Xavier Giro-i-Nieto

Nuclei instance segmentation on histopathology images is of great clinical value for disease analysis. Generally, fully-supervised algorithms for this task require pixel-wise manual annotations, which is especially time-consuming and…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Yang Zhou , Yongjian Wu , Zihua Wang , Bingzheng Wei , Maode Lai , Jianzhong Shou , Yubo Fan , Yan Xu

Multiple Instance Learning (MIL) is increasingly being used as a support tool within clinical settings for pathological diagnosis decisions, achieving high performance and removing the annotation burden. However, existing approaches for…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Sungrae Hong , Kyungeun Kim , Juhyeon Kim , Sol Lee , Jisu Shin , Chanjae Song , Mun Yong Yi

Weakly-supervised classification of histopathology slides is a computationally intensive task, with a typical whole slide image (WSI) containing billions of pixels to process. We propose Discriminative Region Active Sampling for Multiple…

Image and Video Processing · Electrical Eng. & Systems 2023-02-23 Jack Breen , Katie Allen , Kieran Zucker , Geoff Hall , Nicolas M. Orsi , Nishant Ravikumar

Multiple instance learning (MIL) is a promising approach for weakly supervised classification in pathology using whole slide images (WSIs). However, conventional MIL methods such as Attention-Based Deep Multiple Instance Learning (ABMIL)…

Image and Video Processing · Electrical Eng. & Systems 2025-04-28 Hassan Keshvarikhojasteh , Mihail Tifrea , Sibylle Hess , Josien P. W. Pluim , Mitko Veta

Digital pathology has revolutionized the field by enabling the digitization of tissue samples into whole slide images (WSIs). However, the high resolution and large size of WSIs present significant challenges when it comes to applying Deep…

Computer Vision and Pattern Recognition · Computer Science 2025-07-03 Ali Mammadov , Loïc Le Folgoc , Guillaume Hocquet , Pietro Gori

Deep learning based medical image diagnosis has shown great potential in clinical medicine. However, it often suffers two major difficulties in real-world applications: 1) only limited labels are available for model training, due to…

Computer Vision and Pattern Recognition · Computer Science 2020-08-26 Yifan Zhang , Ying Wei , Qingyao Wu , Peilin Zhao , Shuaicheng Niu , Junzhou Huang , Mingkui Tan

Methods for unsupervised domain adaptation (UDA) help to improve the performance of deep neural networks on unseen domains without any labeled data. Especially in medical disciplines such as histopathology, this is crucial since large…

Computer Vision and Pattern Recognition · Computer Science 2023-02-03 Kevin Thandiackal , Luigi Piccinelli , Pushpak Pati , Orcun Goksel

The divergence between labeled training data and unlabeled testing data is a significant challenge for recent deep learning models. Unsupervised domain adaptation (UDA) attempts to solve such a problem. Recent works show that self-training…

Computer Vision and Pattern Recognition · Computer Science 2020-08-28 Ke Mei , Chuang Zhu , Jiaqi Zou , Shanghang Zhang

Multiple instance learning exhibits a powerful approach for whole slide image-based diagnosis in the absence of pixel- or patch-level annotations. In spite of the huge size of hole slide images, the number of individual slides is often…

In Active Domain Adaptation (ADA), one uses Active Learning (AL) to select a subset of images from the target domain, which are then annotated and used for supervised domain adaptation (DA). Given the large performance gap between…

Computer Vision and Pattern Recognition · Computer Science 2022-10-14 Sharat Agarwal , Saket Anand , Chetan Arora