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Deep learning algorithms excel at extracting patterns from raw data, and with large datasets, they have been very successful in computer vision and natural language applications. However, in other domains, large datasets on which to learn…

Machine Learning · Computer Science 2018-09-17 Garrett B. Goh , Khushmeen Sakloth , Charles Siegel , Abhinav Vishnu , Jim Pfaendtner

Apart from discriminative models for classification and object detection tasks, the application of deep convolutional neural networks to basic research utilizing natural imaging data has been somewhat limited; particularly in cases where a…

Computer Vision and Pattern Recognition · Computer Science 2020-09-22 R. Ian Etheredge , Manfred Schartl , Alex Jordan

As machine learning systems get widely adopted for high-stake decisions, quantifying uncertainty over predictions becomes crucial. While modern neural networks are making remarkable gains in terms of predictive accuracy, characterizing…

Machine Learning · Computer Science 2019-06-14 Melanie F. Pradier , Weiwei Pan , Jiayu Yao , Soumya Ghosh , Finale Doshi-velez

Implicit neural representations are powerful for geometric modeling, but their practical use is often limited by the high computational cost of network evaluations. We observe that implicit representations require progressively lower…

Graphics · Computer Science 2026-04-30 Chuanxiang Yang , Junhui Hou , Yuan Liu , Siyu Ren , Guangshun Wei , Taku Komura , Yuanfeng Zhou , Wenping Wang

Recent research in molecular discovery has primarily been devoted to small, drug-like molecules, leaving many similarly important applications in material design without adequate technology. These applications often rely on more complex…

Understanding how neural systems efficiently process information through distributed representations is a fundamental challenge at the interface of neuroscience and machine learning. Recent approaches analyze the statistical and geometrical…

Neurons and Cognition · Quantitative Biology 2025-04-01 Francesca Mignacco , Chi-Ning Chou , SueYeon Chung

Gradient descent typically converges to a single minimum of the training loss without mechanisms to explore alternative minima that may generalize better. Searching for diverse minima directly in high-dimensional parameter space is…

Machine Learning · Computer Science 2025-09-16 Akshay Vegesna , Samip Dahal

Learning disentangled representations is a key step towards effectively discovering and modelling the underlying structure of environments. In the natural sciences, physics has found great success by describing the universe in terms of…

Machine Learning · Computer Science 2020-10-27 Robin Quessard , Thomas D. Barrett , William R. Clements

Recent experiments in neuroscience reveal that task-relevant variables are often encoded in approximately orthogonal subspaces of neural population activity. These disentangled, or abstract, representations have been observed in multiple…

Neurons and Cognition · Quantitative Biology 2026-03-16 Bin Wang , W. Jeffrey Johnston , Stefano Fusi

This paper introduces an Interpretable Neural Network (INN) incorporating spatial information to tackle the opaque parameterization process of random weighted neural networks. The INN leverages spatial information to elucidate the…

Machine Learning · Computer Science 2024-04-16 Jing Nan , Wei Dai

Agents navigating in 3D environments require some form of memory, which should hold a compact and actionable representation of the history of observations useful for decision taking and planning. In most end-to-end learning approaches the…

Robotics · Computer Science 2023-10-02 Guillaume Bono , Leonid Antsfeld , Assem Sadek , Gianluca Monaci , Christian Wolf

A body of recent work in modeling neural activity focuses on recovering low-dimensional latent features that capture the statistical structure of large-scale neural populations. Most such approaches have focused on linear generative models,…

Neurons and Cognition · Quantitative Biology 2016-10-26 Yuanjun Gao , Evan Archer , Liam Paninski , John P. Cunningham

Brains and artificial neural networks compute with continuous variables such as object position or stimulus orientation. However, the complex variability in neural responses makes it difficult to link internal representational structure to…

Neurons and Cognition · Quantitative Biology 2026-03-12 Will Slatton , Chi-Ning Chou , SueYeon Chung

We present a novel 3D mapping method leveraging the recent progress in neural implicit representation for 3D reconstruction. Most existing state-of-the-art neural implicit representation methods are limited to object-level reconstructions…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Stefan Lionar , Lukas Schmid , Cesar Cadena , Roland Siegwart , Andrei Cramariuc

Recent developments in experimental neuroscience make it possible to simultaneously record the activity of thousands of neurons. However, the development of analysis approaches for such large-scale neural recordings have been slower than…

Neurons and Cognition · Quantitative Biology 2022-10-18 Rufus Mitchell-Heggs , Seigfred Prado , Giuseppe P. Gava , Mary Ann Go , Simon R. Schultz

The availability of large-scale neuronal population datasets necessitates new methods to model population dynamics and extract interpretable, scientifically translatable insights. Existing deep learning methods often overlook the biological…

Neurons and Cognition · Quantitative Biology 2024-11-14 Parsa Delavari , Ipek Oruc , Timothy H Murphy

Despite the high performance achieved by deep neural networks on various tasks, extensive studies have demonstrated that small tweaks in the input could fail the model predictions. This issue of deep neural networks has led to a number of…

Machine Learning · Computer Science 2022-02-22 Ming-Chang Chiu , Xuezhe Ma

Other than vector representations, the direct objects of human cognition are generally high-order tensors, such as 2D images and 3D textures. From this fact, two interesting questions naturally arise: How does the human brain represent…

Machine Learning · Computer Science 2013-06-13 Guoqiang Zhong , Mohamed Cheriet

Recent whole brain imaging experiments on $\textit{C. elegans}$ has revealed that the neural population dynamics encode motor commands and stereotyped transitions between behaviors on low dimensional manifolds. Efforts to characterize the…

Quantitative Methods · Quantitative Biology 2020-04-15 Charles Fieseler , Manuel Zimmer , J. Nathan Kutz

In cognitive decoding, researchers aim to characterize a brain region's representations by identifying the cognitive states (e.g., accepting/rejecting a gamble) that can be identified from the region's activity. Deep learning (DL) methods…

Machine Learning · Computer Science 2021-08-17 Armin W. Thomas , Christopher Ré , Russell A. Poldrack