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Liver transplant is an essential therapy performed for severe liver diseases. The fact of scarce liver resources makes the organ assigning crucial. Model for End-stage Liver Disease (MELD) score is a widely adopted criterion when making…

Artificial Intelligence · Computer Science 2023-02-21 Sirui Ding , Ruixiang Tang , Daochen Zha , Na Zou , Kai Zhang , Xiaoqian Jiang , Xia Hu

Liver transplantation often faces fairness challenges across subgroups defined by sensitive attributes such as age group, gender, and race/ethnicity. Machine learning models for outcome prediction can introduce additional biases. Therefore,…

Machine Learning · Computer Science 2024-08-28 Can Li , Dejian Lai , Xiaoqian Jiang , Kai Zhang

Organ transplant is the essential treatment method for some end-stage diseases, such as liver failure. Analyzing the post-transplant cause of death (CoD) after organ transplant provides a powerful tool for clinical decision making,…

Machine Learning · Computer Science 2023-10-09 Sirui Ding , Qiaoyu Tan , Chia-yuan Chang , Na Zou , Kai Zhang , Nathan R. Hoot , Xiaoqian Jiang , Xia Hu

Prognostication for lung cancer, a leading cause of mortality, remains a complex task, as it needs to quantify the associations of risk factors and health events spanning a patient's entire life. One challenge is that an individual's…

Machine Learning · Statistics 2025-08-28 Stephen Salerno , Yi Li

A kidney transplant can improve the life expectancy and quality of life of patients with end-stage renal failure. Even more patients could be helped with a transplant if the rate of kidneys that are discarded and not transplanted could be…

Graft-versus-host disease (GVHD) is a rare but often fatal complication in liver transplantation, with a very high mortality rate. By harnessing multi-modal deep learning methods to integrate heterogeneous and imbalanced electronic health…

Machine Learning · Computer Science 2025-11-18 Yushan Jiang , Shuteng Niu , Dongjin Song , Yichen Wang , Jingna Feng , Xinyue Hu , Liu Yang , Cui Tao

Kidney transplantation is the preferred treatment for end-stage renal disease, yet the scarcity of donors and inefficiencies in allocation systems create major bottlenecks, resulting in prolonged wait times and alarming mortality rates.…

Computer Science and Game Theory · Computer Science 2024-10-15 Sean Berry , Berk Gorgulu , Sait Tunc , Mucahit Cevik , Matthew J Ellis

The burgeoning need for kidney transplantation mandates immediate attention. Mismatch of deceased donor-recipient kidney leads to post-transplant death. To ensure ideal kidney donor-recipient match and minimize post-transplant deaths, the…

Computers and Society · Computer Science 2019-08-22 Ehsan Khan , Avishek Choudhury , Amy L Friedman , Daehan Won

Fairness in clinical prediction models remains a persistent challenge, particularly in high-stakes applications such as spinal fusion surgery for scoliosis, where patient outcomes exhibit substantial heterogeneity. Many existing fairness…

Machine Learning · Computer Science 2025-12-02 Yining Yuan , J. Ben Tamo , Wenqi Shi , Yishan Zhong , Micky C. Nnamdi , B. Randall Brenn , Steven W. Hwang , May D. Wang

25% of people who received a liver transplant will go on to develop diabetes within the next 5 years. These thousands of individuals are at 2-fold higher risk of cardiovascular events, graft loss, infections, as well as lower long-term…

Machine Learning · Computer Science 2019-06-06 Angeline Yasodhara , Mamatha Bhat , Anna Goldenberg

Postoperative complications pose a significant challenge in the healthcare industry, resulting in elevated healthcare expenses and prolonged hospital stays, and in rare instances, patient mortality. To improve patient outcomes and reduce…

Machine Learning · Computer Science 2023-06-07 Reza Shirkavand , Fei Zhang , Heng Huang

A kidney exchange program, also called a kidney paired donation program, can be viewed as a repeated, dynamic trading and allocation mechanism. This suggests that a dynamic algorithm for transplant exchange selection may have superior…

Optimization and Control · Mathematics 2023-09-26 Margarida Carvalho , Alison Caulfield , Yi Lin , Adrian Vetta

In recent days, Deep Learning (DL) techniques have become an emerging transformation in the field of machine learning, artificial intelligence, computer vision, and so on. Subsequently, researchers and industries have been highly endorsed…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 P. Kalaiselvi , S. Anusuya

We suggest that deep learning can be used for pre-screening cancer by analyzing demographic and anthropometric information of patients, as well as biological markers obtained from routine blood samples and relative risks obtained from…

Machine Learning · Statistics 2023-02-07 Rolando Gonzales Martinez , Daan-Max van Dongen

Liver allograft failure occurs in approximately 20% of liver transplant recipients within five years post-transplant, leading to mortality or the need for retransplantation. Providing an accurate and interpretable model for individualized…

Machine Learning · Computer Science 2024-08-13 Xiang Gao , Michael Cooper , Maryam Naghibzadeh , Amirhossein Azhie , Mamatha Bhat , Rahul G. Krishnan

Organ transplants can improve the life expectancy and quality of life for the recipient but carries the risk of serious post-operative complications, such as septic shock and organ rejection. The probability of a successful transplant…

Machine Learning · Computer Science 2016-11-15 Jinsung Yoon , Ahmed M. Alaa , Martin Cadeiras , Mihaela van der Schaar

Medical institutions are considering the use of LLMs in high-stakes clinical decision-making, such as organ allocation. In such sensitive use cases, evaluating fairness is imperative. However, existing evaluation methods often fall short;…

Machine Learning · Computer Science 2026-01-16 Brian Hyeongseok Kim , Hannah Murray , Isabelle Lee , Jason Byun , Joshua Lum , Dani Yogatama , Evi Micha

Liver infection is a common disease, which poses a great threat to human health, but there is still able to identify an optimal technique that can be used on large-level screening. This paper deals with ML algorithms using different data…

Machine Learning · Computer Science 2023-05-16 P. Deivendran , S. Selvakanmani , S. Jegadeesan , V. Vinoth Kumar

With the current ongoing debate about fairness, explainability and transparency of machine learning models, their application in high-impact clinical decision-making systems must be scrutinized. We consider a real-life example of risk…

Machine Learning · Computer Science 2020-11-13 Sandhya Tripathi , Bradley A. Fritz , Mohamed Abdelhack , Michael S. Avidan , Yixin Chen , Christopher R. King

Predicting the incidence of complex chronic conditions such as heart failure is challenging. Deep learning models applied to rich electronic health records may improve prediction but remain unexplainable hampering their wider use in medical…

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