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Single-cell RNA-seq data allow the quantification of cell type differences across a growing set of biological contexts. However, pinpointing a small subset of genomic features explaining this variability can be ill-defined and…

Machine Learning · Statistics 2022-07-29 Nabeel Sarwar , Wilson Gregory , George A Kevrekidis , Soledad Villar , Bianca Dumitrascu

Artificial Intelligence (AI) has emerged as a valuable tool for assisting radiologists in breast cancer detection and diagnosis. However, the success of AI applications in this domain is restricted by the quantity and quality of available…

Computer Vision and Pattern Recognition · Computer Science 2024-05-31 Marta Buetas Arcas , Richard Osuala , Karim Lekadir , Oliver Díaz

Single-cell technologies are revolutionizing the entire field of biology. The large volumes of data generated by single-cell technologies are high-dimensional, sparse, heterogeneous, and have complicated dependency structures, making…

Gestures perform a variety of communicative functions that powerfully influence human face-to-face interaction. How this communicative function is achieved varies greatly between individuals and depends on the role of the speaker and the…

Human-Computer Interaction · Computer Science 2023-10-24 Laura B. Hensel , Nutchanon Yongsatianchot , Parisa Torshizi , Elena Minucci , Stacy Marsella

Large language models (LLMs) exhibited powerful capability in various natural language processing tasks. This work focuses on exploring LLM performance on zero-shot information extraction, with a focus on the ChatGPT and named entity…

Computation and Language · Computer Science 2023-10-17 Tingyu Xie , Qi Li , Jian Zhang , Yan Zhang , Zuozhu Liu , Hongwei Wang

The exploration of cellular heterogeneity within the tumor microenvironment (TME) via single-cell RNA sequencing (scRNA-seq) is essential for understanding cancer progression and response to therapy. Current scRNA-seq approaches, however,…

Genomics · Quantitative Biology 2025-02-06 Yu-An Huang , Yue-Chao Li , Hai-Ru You , Jie Pan , Xiyue Cao , Xinyuan Li , Zhi-An Huang , Zhu-Hong You

In the rapidly evolving field of business process management, there is a growing need for analytical tools that can transform complex data into actionable insights. This research introduces a novel approach by integrating Large Language…

Computation and Language · Computer Science 2024-05-20 Mehrdad Agha Mohammad Ali Kermani , Hamid Reza Seddighi , Mehrdad Maghsoudi

We systematically study how three large language models with code capabilities - CodeT5, Codex, and ChatGPT - generalize to out-of-domain data. We consider two fundamental applications - code summarization, and code generation. We split…

Computation and Language · Computer Science 2023-12-07 Shushan Arakelyan , Rocktim Jyoti Das , Yi Mao , Xiang Ren

Single-cell trajectory analysis aims to reconstruct the biological developmental processes of cells as they evolve over time, leveraging temporal correlations in gene expression. During cellular development, gene expression patterns…

Applications · Statistics 2026-03-30 Junhao Zhu , Kevin Zhang , Zhaolei Zhang , Dehan Kong

ChatGPT explores a strategic blueprint of question answering (QA) in delivering medical diagnosis, treatment recommendations, and other healthcare support. This is achieved through the increasing incorporation of medical domain data via…

Computation and Language · Computer Science 2024-01-23 Qing Li , Lei Li , Yu Li

The development of large language models (LLMs) such as ChatGPT has brought a lot of attention recently. However, their evaluation in the benchmark academic datasets remains under-explored due to the difficulty of evaluating the generative…

Computation and Language · Computer Science 2023-07-07 Md Tahmid Rahman Laskar , M Saiful Bari , Mizanur Rahman , Md Amran Hossen Bhuiyan , Shafiq Joty , Jimmy Xiangji Huang

Large language models (LLMs) are transforming cellular biology by enabling the development of "virtual cells"--computational systems that represent, predict, and reason about cellular states and behaviors. This work provides a comprehensive…

Computation and Language · Computer Science 2025-10-10 Krinos Li , Xianglu Xiao , Shenglong Deng , Lucas He , Zijun Zhong , Yuanjie Zou , Zhonghao Zhan , Zheng Hui , Weiye Bao , Guang Yang

Cytometry enables precise single-cell phenotyping within heterogeneous populations. These cell types are traditionally annotated via manual gating, but this method suffers from a lack of reproducibility and sensitivity to batch-effect.…

This paper takes an exploratory approach to examine the use of ChatGPT for pattern mining. It proposes an eight-step collaborative process that combines human insight with AI capabilities to extract patterns from known uses. The paper…

Artificial Intelligence · Computer Science 2024-12-24 Michael Weiss

Cellular networks, e.g., 4G/5G, rely on complex technical specifications to ensure correct functionality; however, these specifications often contain flaws or ambiguities. In this paper, we investigate the application of Large Language…

Cryptography and Security · Computer Science 2026-01-06 Jianshuo Dong , Yuanjie Li , Jun Liu , Hewu Li , Han Qiu

Large Language Models (LLMs), exemplified by ChatGPT, have significantly reshaped text generation, particularly in the realm of writing assistance. While ethical considerations underscore the importance of transparently acknowledging LLM…

Information Retrieval · Computer Science 2025-09-03 Teddy Lazebnik , Ariel Rosenfeld

State-of-the-art supervised NLP models achieve high accuracy but are also susceptible to failures on inputs from low-data regimes, such as domains that are not represented in training data. As an approximation to collecting ground-truth…

Computation and Language · Computer Science 2023-06-29 Parikshit Bansal , Amit Sharma

There is enormous enthusiasm and concerns in using large language models (LLMs) in healthcare, yet current assumptions are all based on general-purpose LLMs such as ChatGPT. This study develops a clinical generative LLM, GatorTronGPT, using…

Single-cell RNA sequencing (scRNA-seq) data analysis is crucial for biological research, as it enables the precise characterization of cellular heterogeneity. However, manual manipulation of various tools to achieve desired outcomes can be…

Artificial Intelligence · Computer Science 2024-07-16 Yihang Xiao , Jinyi Liu , Yan Zheng , Xiaohan Xie , Jianye Hao , Mingzhi Li , Ruitao Wang , Fei Ni , Yuxiao Li , Jintian Luo , Shaoqing Jiao , Jiajie Peng

Human annotation of training samples is expensive, laborious, and sometimes challenging, especially for Natural Language Processing (NLP) tasks. To reduce the labeling cost and enhance the sample efficiency, Active Learning (AL) technique…

Computation and Language · Computer Science 2024-01-17 Xuesong Wang
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