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Biofilms are communities of bacteria that exhibit a multitude of multiscale biomechanical behaviors. Recent experimental advances have lead to characterizations of these behaviors in terms of measurements of the viscoelastic moduli of…

Cell Behavior · Quantitative Biology 2017-07-19 Jay A. Stotsky , Vanja Dukic , David M. Bortz

Advances in cellular imaging technologies, especially those based on fluorescence in situ hybridization (FISH) now allow detailed visualization of the spatial organization of human or bacterial cells. Quantifying this spatial organization…

Metagenomics has lowered the barrier to microbial discovery--enabling the identification of novel microbes without isolation--but cultures remain imperative for the deep study of microbes. Cultivation and isolation of non-model microbes…

Molecular Networks · Quantitative Biology 2026-02-26 Olivia Bulka , Chabname Ghassemi Nedjad , Loïc Paulevé , Sylvain Prigent , Clémence Frioux

Multi-modality of color and depth, i.e., RGB-D, is of great importance in recent research of indoor scene recognition. In this kind of data representation, depth map is able to describe the 3D structure of scenes and geometric relations…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Qiong Liu , Ruofei Xiong , Xingzhen Chen , Muyao Peng , You Yang

Random walks and related spatial stochastic models have been used in a range of application areas including animal and plant ecology, infectious disease epidemiology, developmental biology, wound healing, and oncology. Classical random walk…

Populations and Evolution · Quantitative Biology 2025-08-22 Michael J. Plank , Matthew J. Simpson , Ruth E. Baker

Recently there has been increased interest in fitting generative graph models to real-world networks. In particular, Bl\"asius et al. have proposed a framework for systematic evaluation of the expressivity of random graph models. We extend…

Social and Information Networks · Computer Science 2024-05-14 Benjamin Dayan , Marc Kaufmann , Ulysse Schaller

Hypergraphs offer an explicit formalism to describe multibody interactions in complex systems. To connect dynamics and function in systems with these higher-order interactions, network scientists have generalised random-walk models to…

Physics and Society · Physics 2022-06-02 Anton Eriksson , Daniel Edler , Alexis Rojas , Martin Rosvall

As they carry great potential for modeling complex interactions, graph neural network (GNN)-based methods have been widely used to predict quantum mechanical properties of molecules. Most of the existing methods treat molecules as molecular…

Machine Learning · Computer Science 2020-09-29 Zeren Shui , George Karypis

Envelope model also known as multivariate regression model was proposed to solve the multiple response regression problems. It measures the linear association between predictors and multiple responses by using the minimal reducing subspace…

Methodology · Statistics 2018-05-07 Bochao Jia

A gene expression compendium is a heterogeneous collection of gene expression experiments assembled from data collected for diverse purposes. The widely varied experimental conditions and genetic backgrounds across samples creates a…

Quantitative Methods · Quantitative Biology 2022-03-29 Alexandra J. Lee , Taylor Reiter , Georgia Doing , Julia Oh , Deborah A. Hogan , Casey S. Greene

Biological systems, from a cell to the human brain, are inherently complex. A powerful representation of such systems, described by an intricate web of relationships across multiple scales, is provided by complex networks. Recently, several…

Quantitative Methods · Quantitative Biology 2018-02-06 M. De Domenico

Integrative network modeling of data arising from multiple genomic platforms provides insight into the holistic picture of the interactive system, as well as the flow of information across many disease domains including cancer. The basic…

Methodology · Statistics 2020-02-18 Min Jin Ha , Francesco Stingo , Veerabhadran Baladandayuthapani

In the past two decades, significant advances have been made in understanding the structural and functional properties of biological networks, via graph-theoretic analysis. In general, most graph-theoretic studies are conducted in the…

Physics and Society · Physics 2013-10-21 Michelle Rudolph-Lilith , Lyle E. Muller

The microbiome-gut-brain-axis field is multidisciplinary, benefiting from the expertise of microbiology, ecology, psychiatry, computational biology, and epidemiology amongst other disciplines. As the field matures and moves beyond a basic…

Genomics · Quantitative Biology 2023-12-11 Thomaz F. S. Bastiaanssen , Thomas P. Quinn , Amy Loughman

The inherent complexity of biological systems gives rise to complicated mechanistic models with a large number of parameters. On the other hand, the collective behavior of these systems can often be characterized by a relatively small…

Quantitative Methods · Quantitative Biology 2016-06-15 Mark K. Transtrum , Peng Qiu

The dynamic instability of the living systems and the "superposition" of different forms of randomness are viewed as a component of the contingently increasing organization of life along evolution. We briefly survey how classical and…

Other Quantitative Biology · Quantitative Biology 2011-04-07 Marcello Buiatti , Giuseppe Longo

The use of network theory to model disease propagation on populations introduces important elements of reality to the classical epidemiological models. The use of random geometric graphs (RGG) is one of such network models that allows for…

Physics and Society · Physics 2016-12-21 Ernesto Estrada , Sandro Meloni , Matthew Sheerin , Yamir Moreno

Multi-behavior recommendation exploits multiple types of user-item interactions to alleviate the data sparsity problem faced by the traditional models that often utilize only one type of interaction for recommendation. In real scenarios,…

Information Retrieval · Computer Science 2023-07-13 Mingshi Yan , Zhiyong Cheng , Chen Gao , Jing Sun , Fan Liu , Fuming Sun , Haojie Li

Biomedical networks (or graphs) are universal descriptors for systems of interacting elements, from molecular interactions and disease co-morbidity to healthcare systems and scientific knowledge. Advances in artificial intelligence,…

Machine Learning · Computer Science 2025-02-07 Michelle M. Li , Kexin Huang , Marinka Zitnik

Graphical modeling is a widely used tool for analyzing conditional dependencies between variables and traditional methods may struggle to capture shared and distinct structures in multi-group or multi-condition settings. Joint graphical…

Methodology · Statistics 2025-03-10 Duong H. T. Vo , Nelofer Syed , Thomas Thorne