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Denoising diffusion models have emerged as a powerful tool for various image generation and editing tasks, facilitating the synthesis of visual content in an unconditional or input-conditional manner. The core idea behind them is learning…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Yi Huang , Jiancheng Huang , Yifan Liu , Mingfu Yan , Jiaxi Lv , Jianzhuang Liu , Wei Xiong , He Zhang , Liangliang Cao , Shifeng Chen

Accurately translating medical images between different modalities, such as Computed Tomography (CT) to Magnetic Resonance Imaging (MRI), has numerous downstream clinical and machine learning applications. While several methods have been…

Image and Video Processing · Electrical Eng. & Systems 2025-12-03 Yuwen Chen , Nicholas Konz , Hanxue Gu , Haoyu Dong , Yaqian Chen , Lin Li , Jisoo Lee , Maciej A. Mazurowski

Diffusion models (DMs) have revolutionized generative learning. They utilize a diffusion process to encode data into a simple Gaussian distribution. However, encoding a complex, potentially multimodal data distribution into a single…

Machine Learning · Computer Science 2024-07-04 Yilun Xu , Gabriele Corso , Tommi Jaakkola , Arash Vahdat , Karsten Kreis

Recently, research on denoising diffusion models has expanded its application to the field of image restoration. Traditional diffusion-based image restoration methods utilize degraded images as conditional input to effectively guide the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-25 Zhenning Shi , Haoshuai Zheng , Chen Xu , Changsheng Dong , Bin Pan , Xueshuo Xie , Along He , Tao Li , Huazhu Fu

Low-dose CT imaging requires reconstruction from noisy indirect measurements which can be defined as an ill-posed linear inverse problem. In addition to conventional FBP method in CT imaging, recent compressed sensing based methods exploit…

Image and Video Processing · Electrical Eng. & Systems 2025-11-14 Mehmet Ozan Unal , Metin Ertas , Isa Yildirim

Denoising diffusion models (DDMs) have led to staggering performance leaps in image generation, editing and restoration. However, existing DDMs use very large datasets for training. Here, we introduce a framework for training a DDM on a…

Computer Vision and Pattern Recognition · Computer Science 2023-06-08 Vladimir Kulikov , Shahar Yadin , Matan Kleiner , Tomer Michaeli

The extensive use of medical CT has raised a public concern over the radiation dose to the patient. Reducing the radiation dose leads to increased CT image noise and artifacts, which can adversely affect not only the radiologists judgement…

Image and Video Processing · Electrical Eng. & Systems 2021-07-13 Jiajin Zhang , Hanqing Chao , Xuanang Xu , Chuang Niu , Ge Wang , Pingkun Yan

The acquisition conditions for low-dose and high-dose CT images are usually different, so that the shifts in the CT numbers often occur. Accordingly, unsupervised deep learning-based approaches, which learn the target image distribution,…

Image and Video Processing · Electrical Eng. & Systems 2022-07-15 Chanyong Jung , Joonhyung Lee , Sunkyoung You , Jong Chul Ye

Image-generative artificial intelligence (AI) has garnered significant attention in recent years. In particular, the diffusion model, a core component of generative AI, produces high-quality images with rich diversity. In this study, we…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Sho Ozaki , Shizuo Kaji , Toshikazu Imae , Kanabu Nawa , Hideomi Yamashita , Keiichi Nakagawa

Diffusion models have revolutionized image synthesis, setting new benchmarks in quality and creativity. However, their widespread adoption is hindered by the intensive computation required during the iterative denoising process.…

Computer Vision and Pattern Recognition · Computer Science 2024-09-19 Huanpeng Chu , Wei Wu , Chengjie Zang , Kun Yuan

Deep learning has shown the capability to substantially accelerate MRI reconstruction while acquiring fewer measurements. Recently, diffusion models have gained burgeoning interests as a novel group of deep learning-based generative…

Image and Video Processing · Electrical Eng. & Systems 2023-06-27 Jiahao Huang , Angelica Aviles-Rivero , Carola-Bibiane Schönlieb , Guang Yang

Rb-82 dynamic cardiac PET imaging is widely used for the clinical diagnosis of coronary artery disease (CAD), but its short half-life results in high noise levels that degrade dynamic frame quality and parametric imaging. The lack of paired…

Cross-dose denoising for low-dose positron emission tomography (LDPET) has been proposed to address the limited generalization of models trained at a single noise level. However, neural networks trained on a specific dose level often fail…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Yichao Liu , Zongru Shao , Yueyang Teng , Junwen Guo

Diffusion and flow-based models have enabled significant progress in generation tasks across various modalities and have recently found applications in predictive learning. However, unlike typical generation tasks that encourage sample…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Yu Zhang , Xingzhuo Guo , Haoran Xu , Jialong Wu , Mingsheng Long

Utilizing a low-dose CT approach significantly reduces the radiation exposure for patients, yet it introduces challenges, such as increased noise and artifacts in the resultant images, which can hinder accurate medical diagnostics.…

Image and Video Processing · Electrical Eng. & Systems 2024-04-03 Helena Shawn , Thompson Chyrikov , Jacob Lanet , Lam-chi Chen , Jim Zhao , Christina Chajo

Radiomics is an active area of research in medical image analysis, the low reproducibility of radiomics has limited its applicability to clinical practice. This issue is especially prominent when radiomic features are calculated from noisy…

Quantitative Methods · Quantitative Biology 2021-08-16 Junhua Chen , Chong Zhang , Alberto Traverso , Ivan Zhovannik , Andre Dekker , Leonard Wee , Inigo Bermejo

Discrete diffusion models generate sequences by iteratively denoising samples corrupted by categorical noise, offering an appealing alternative to autoregressive decoding for structured and symbolic generation. However, standard training…

Machine Learning · Computer Science 2026-02-04 Huu Binh Ta , Michael Cardei , Alvaro Velasquez , Ferdinando Fioretto

Computed tomography from a low radiation dose (LDCT) is challenging due to high noise in the projection data. Popular approaches for LDCT image reconstruction are two-stage methods, typically consisting of the filtered backprojection (FBP)…

Image and Video Processing · Electrical Eng. & Systems 2025-03-17 Tim Selig , Thomas März , Martin Storath , Andreas Weinmann

Diffusion models (DMs) excel in image generation but suffer from slow inference and training-inference discrepancies. Although gradient-based solvers for DMs accelerate denoising inference, they often lack theoretical foundations in…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Shigui Li , Wei Chen , Delu Zeng

Advances in endoscopy use in surgeries face challenges like inadequate lighting. Deep learning, notably the Denoising Diffusion Probabilistic Model (DDPM), holds promise for low-light image enhancement in the medical field. However, DDPMs…

Image and Video Processing · Electrical Eng. & Systems 2024-05-20 Tong Chen , Qingcheng Lyu , Long Bai , Erjian Guo , Huxin Gao , Xiaoxiao Yang , Hongliang Ren , Luping Zhou